Brian M Baker

University Of Notre Dame

$12,423,792

Attributed

$16,537,495

Total exposure

Grants

Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.7M · FY2005–25

$2M$1.5M$1M$500K$0

'05

'06

'07

'08

'09

'10

'11

'12

'13

'14

'15

'16

'17

'18

'19

'20

'21

'22

'23

'24

'25

Funding mix

By agency

NIH$16,537,495 · 10

By mechanism

R01$10,762,846 · 4

R35$4,378,287 · 1

R21$923,093 · 2

S10$467,782 · 2

P41$5,487 · 1

Top collaborators

Most similar at University Of Notre Dame

Same institution · by research overlap

David A Hildeman$13,398,639

Others in their field

Top investigators on “Specificity”

Sonia M Thomas · Research Triangle Institute$700,865,642
Eric S Lander · Whitehead Institute For Biomedical Res$527,312,131
Barton F Haynes · Duke University$483,626,898
Tracy L Nolen · Research Triangle Institute$474,487,152
David Heimbrook · Leidos Biomedical Research, Inc.$395,980,920
Margaret Juliana McElrath · Fred Hutchinson Cancer Center$381,706,339

Research focus

SpecificityT-LymphocytePeptidesPeptide/Mhc ComplexDesignT-Cell ReceptorStructureProteinsCross ReactivityPropertyCellular ImmunityAffinityMolecularComplexLigandsImmune SystemBiophysicsAntigensImmunotherapySuccessBaseInsightImmuneReceptor

Grant awards (45)

Mechanisms and manipulation of force dependent behavior in T cell biology$735,147

R01 · FY2025 · AI · contact PI

Bringing alloreactivity into focus with the lens of TCR cross-reactivity$459,439

R21 · FY2025 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$422,550

R35 · FY2025 · GM · contact PI

Mechanisms and manipulation of force dependent behavior in T cell biology$757,883

R01 · FY2024 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$422,550

R35 · FY2024 · GM · contact PI

Decoding human T-cell allospecificity$198,878

R21 · FY2024 · AI · contact PI

Mechanisms and manipulation of force dependent behavior in T cell biology$771,569

R01 · FY2023 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$422,550

R35 · FY2023 · GM · contact PI

Decoding human T-cell allospecificity$264,776

R21 · FY2023 · AI · contact PI

GPU-based computing for structural biophysics in immune recognition$230,415

R35 · FY2023 · GM · contact PI

Structural biophysics and molecular design in cellular immunity$422,550

R35 · FY2022 · GM · contact PI

Building better T cell receptors for targeted immunotherapy$686,715

R01 · FY2021 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$422,550

R35 · FY2021 · GM · contact PI

Building better T cell receptors for targeted immunotherapy$755,580

R01 · FY2020 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$394,284

R35 · FY2020 · GM · contact PI

BIACORE T200 SPR FOR NOTRE DAME BIOPHYSICS INSTRUMENTATION CORE (BIC) FACILITY$342,782

S10 · FY2020 · OD · contact PI

Flow cytometry and cell sorting for structural biophysics in immune recognition$211,853

R35 · FY2020 · GM · contact PI

Building better T cell receptors for targeted immunotherapy$828,987

R01 · FY2019 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$394,284

R35 · FY2019 · GM · contact PI

Building better T cell receptors for targeted immunotherapy$720,706

R01 · FY2018 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$394,284

R35 · FY2018 · GM · contact PI

: Building better T cell receptors for targeted immunotherapy$56,115

R01 · FY2018 · AI · contact PI

Building better T cell receptors for targeted immunotherapy$772,935

R01 · FY2017 · AI · contact PI

Structural biophysics and molecular design in cellular immunity$394,284

R35 · FY2017 · GM · contact PI

Development of a Computational Framework for TCR Engineering$301,847

R01 · FY2016 · GM

Structural biophysics and molecular design in cellular immunity$169,202

R35 · FY2016 · GM · contact PI

High capacity protein purification for structural immunology$76,931

R35 · FY2016 · GM · contact PI

Physical Basis for T Cell Receptor Binding and Activity$304,000

R01 · FY2015 · GM · contact PI

Development of a Computational Framework for TCR Engineering$301,847

R01 · FY2015 · GM

Crystallization robotics for structural immunology$100,080

R01 · FY2015 · GM · contact PI

Physical Basis for T Cell Receptor Binding and Activity$304,000

R01 · FY2014 · GM · contact PI

Development of a Computational Framework for TCR Engineering$301,607

R01 · FY2014 · GM

Development of a Computational Framework for TCR Engineering$313,375

R01 · FY2013 · GM

Physical Basis for T Cell Receptor Binding and Activity$273,742

R01 · FY2012 · GM · contact PI

Physical Basis for T Cell Receptor Binding and Activity$273,742

R01 · FY2011 · GM · contact PI

T CELL RECEPTOR RECOGNITION IN MOLECULAR AND CANCER IMMUNOLOGY$5,487

P41 · FY2011 · RR · contact PI

Physical Basis for T Cell Receptor Binding and Activity$274,428

R01 · FY2010 · GM · contact PI

Acquisition of an ITC200 isothermal titration calorimeter for Univ. of Notre Dame$125,000

S10 · FY2010 · RR · contact PI

Physical Basis for T Cell Receptor Binding and Activity$336,407

R01 · FY2009 · GM · contact PI

Physical Basis for T Cell Receptor Binding and Activity$291,900

R01 · FY2009 · GM · contact PI

Physical basis for T cell receptor binding and activity$246,408

R01 · FY2007 · GM · contact PI

Physical basis for T cell receptor binding and activity$253,768

R01 · FY2006 · GM · contact PI

Physical basis for T cell receptor binding and activity$259,875

R01 · FY2005 · GM

Physical basis for T cell receptor binding and activity$251,388

R01 · FY2004 · GM

Physical basis for T cell receptor binding and activity$288,795

R01 · FY2003 · GM