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Alexander J Varshavsky

California Institute Of Technology

Google Scholar ↗PubMed ↗ORCID ↗

$30,180,913

Attributed

$30,180,913

Total exposure

6

Grants

5

Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $1.6M · FY2005–25

$2M$1.5M$1M$500K$0

'05

'06

'07

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'25

Funding mix

By agency

NIH$30,180,913 · 6

By mechanism

R01$25,311,802 · 3

R37$4,396,611 · 1

R21$312,000 · 1

R56$160,500 · 1

Top collaborators

No co-investigators on record.

Most similar at California Institute Of Technology

Same institution · by research overlap

Others in their field

Top investigators on “Ubiquitin”

Rama K Mallampalli · Ohio State University$30,048,445
Ze'ev A Ronai · Mount Sinai School Of Medicine Of Cuny$28,079,720
Jeffrey Wade Harper · Dana-Farber Cancer Inst$25,447,325
Daniel J Finley · Harvard University (Medical School)$23,295,342
Mark Hochstrasser · University Of Chicago$18,674,039
Inder Mohan Verma · Salk Institute For Biological Studies$18,627,656

Research focus

UbiquitinProtein DegradationProteolysisProteinsGrantPlaySaccharomyces CerevisiaePathway InteractionsN-TerminalMalignant NeoplasmsYeastsLaboratoriesUbiquitin LigaseBiological ProcessPhysiologicalDefectNerve DegenerationSyndromeHuman DiseaseHemeMedicalIn VivoRegulationStem

Grant awards (58)

New Mechanisms and Functions of the Pro/N Degron and Arg/N-Degron Pathways$598,988

R01 · FY2025 · DK · contact PI

Superchanneling, Regulation of Caspases, and Site-Specific Control of RNA$484,500

R01 · FY2025 · GM · contact PI

New Mechanisms and Functions of the Pro/N Degron and Arg/N-Degron Pathways$575,028

R01 · FY2024 · DK · contact PI

Superchanneling, Regulation of Caspases, and Site-Specific Control of RNA$484,500

R01 · FY2024 · GM · contact PI

New Mechanisms and Functions of the Pro/N Degron and Arg/N-Degron Pathways$598,988

R01 · FY2023 · DK · contact PI

New Functions and Specificities of the Arg/N-Degron Pathway$566,100

R01 · FY2023 · GM · contact PI

New Mechanisms and Functions of the Pro/N Degron and Arg/N-Degron Pathways$598,988

R01 · FY2022 · DK · contact PI

New Functions and Specificities of the Arg/N-Degron Pathway$566,100

R01 · FY2022 · GM · contact PI

The GID Ubiquitin Ligase and the Pro/N-End Rule Pathway in Yeast and Mammals$595,650

R01 · FY2021 · DK · contact PI

New Functions and Specificities of the Arg/N-Degron Pathway$566,100

R01 · FY2021 · GM · contact PI

The GID Ubiquitin Ligase and the Pro/N-End Rule Pathway in Yeast and Mammals$604,650

R01 · FY2020 · DK · contact PI

New Functions and Specificities of the Arg/N-Degron Pathway$596,100

R01 · FY2020 · GM · contact PI

The GID Ubiquitin Ligase and the Pro/N-End Rule Pathway in Yeast and Mammals$604,650

R01 · FY2019 · DK · contact PI

The GID Ubiquitin Ligase and the Pro/N-End Rule Pathway in Yeast and Mammals$625,650

R01 · FY2018 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$589,090

R01 · FY2018 · GM · contact PI

The GID Ubiquitin Ligase and the Pro/N-End Rule Pathway in Yeast and Mammals$617,650

R01 · FY2017 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$595,738

R01 · FY2017 · GM · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$579,593

R01 · FY2016 · GM · contact PI

The Mammalian Arg/N-End Rule Pathway: Substrates, Functions, and Mechanisms$520,669

R01 · FY2016 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$600,011

R01 · FY2015 · GM · contact PI

The Mammalian Arg/N-End Rule Pathway: Substrates, Functions, and Mechanisms$526,759

R01 · FY2015 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$587,621

R01 · FY2014 · GM · contact PI

The Mammalian Arg/N-End Rule Pathway: Substrates, Functions, and Mechanisms$538,939

R01 · FY2014 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$572,813

R01 · FY2013 · GM · contact PI

The Mammalian Arg/N-End Rule Pathway: Substrates, Functions, and Mechanisms$550,684

R01 · FY2013 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$605,644

R01 · FY2012 · GM · contact PI

Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule Pathway$548,159

R01 · FY2012 · DK · contact PI

N-Terminal Acetylation and Protein Degradation by the N-End Rule Pathway$616,966

R01 · FY2011 · GM · contact PI

Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule Pathway$548,159

R01 · FY2011 · DK · contact PI

Split Proteins As Boolean Circuits and Drugs of a New Kind$314,612

R01 · FY2011 · GM · contact PI

Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule Pathway$651,543

R01 · FY2010 · DK · contact PI

The Functions, Mechanisms, and Regulation of N-Terminal Arginylation$626,284

R01 · FY2010 · GM · contact PI

Split Proteins As Boolean Circuits and Drugs of a New Kind$317,790

R01 · FY2010 · GM · contact PI

Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule Pathway$28,000

R01 · FY2010 · DK · contact PI

Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule Pathway$641,917

R01 · FY2009 · DK · contact PI

The Functions, Mechanisms, and Regulation of N-Terminal Arginylation$609,703

R01 · FY2009 · GM · contact PI

Split Proteins As Boolean Circuits and Drugs of a New Kind$321,000

R01 · FY2009 · GM · contact PI

The Functions, Mechanisms, and Regulation of N-Terminal Arginylation$592,178

R01 · FY2008 · GM · contact PI

Split Proteins As Boolean Circuits and Drugs of a New Kind$321,000

R01 · FY2008 · GM · contact PI

Ubiquitin Ligases, Mechanisms and Functions of the N-End Rule Pathway$160,500

R56 · FY2008 · DK · contact PI

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$631,697

R37 · FY2007 · DK · contact PI

The Functions, Mechanisms, and Regulation of N-Terminal Arginylation$604,841

R01 · FY2007 · GM · contact PI

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$631,847

R37 · FY2006 · DK · contact PI

Functions of Ubiquitin-Containing Proteins$583,302

R01 · FY2006 · GM · contact PI

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$627,436

R37 · FY2005 · DK

Functions of Ubiquitin-Containing Proteins$589,698

R01 · FY2005 · GM

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$612,365

R37 · FY2004 · DK

Functions of Ubiquitin-Containing Proteins$558,053

R01 · FY2004 · GM

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$593,820

R37 · FY2003 · DK

Functions of Ubiquitin-Containing Proteins$552,490

R01 · FY2003 · GM

FUNCTIONS OF UBIQUITIN CONTAINING PROTEINS$454,359

R01 · FY2002 · GM

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$446,014

R37 · FY2002 · DK

FUNCTIONS OF UBIQUITIN CONTAINING PROTEINS$446,510

R01 · FY2001 · GM

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$433,022

R37 · FY2001 · DK

MULTITARGET DRUGS: VERIFICATION-OF-PRINCIPLE STUDIES$156,000

R21 · FY2001 · CA

FUNCTIONS OF UBIQUITIN CONTAINING PROTEINS$434,035

R01 · FY2000 · GM

MECHANICS AND FUNCTIONS OF THE N-END RULE PATHWAY$420,410

R37 · FY2000 · DK

MULTITARGET DRUGS: VERIFICATION-OF-PRINCIPLE STUDIES$156,000

R21 · FY2000 · CA