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Seth M Cohen

Massachusetts Institute Of Technology

$8,971,153
Attributed
$11,511,299
Total exposure
12
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.2M · FY200625
$2M$1.5M$1M$500K$0
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
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'22
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'24
'25

Funding mix

By agency

NIH$11,511,299 · 12

By mechanism

R01$9,598,322 · 5
R21$1,735,028 · 5
R03$153,032 · 1
F32$24,917 · 1

Top collaborators

Most similar at Massachusetts Institute Of Technology

Same institution · by research overlap

Others in their field

Top investigators on “Metals

Research focus

MetalsIonsActive SitesDesignProgramsInhibitor/AntagonistEnzymesMetalloenzymeMalignant NeoplasmsBaseInnovationProteinsPharmaceutical PreparationsLibrariesComplexLeadAffinityBiochemicalIn VitroLaboratoriesZincDrug DiscoveryPlayCells

Grant awards (40)

Inhibitors of Cu-only Superoxide Dismutases as Novel Antifungals$221,799
R21 · FY2025 · AI · contact PI
Metal-binding Isosteres for Influenza Endonuclease Inhibitors and Beyond$370,748
R01 · FY2024 · AI · contact PI
Inhibitors of Cu-only Superoxide Dismutases as Novel Antifungals$202,166
R21 · FY2024 · AI · contact PI
Fragment-based Discovery of COMT Inhibitors as a Novel Pharmacotherapy for Alcoholism$175,863
R21 · FY2024 · AA · contact PI
Targeting Metal-Dependent Epigenetic Modulators via MetalloPROTACs$159,260
R21 · FY2024 · CA
Metal-binding Isosteres for Influenza Endonuclease Inhibitors and Beyond$370,748
R01 · FY2023 · AI · contact PI
Fragment-based Discovery of COMT Inhibitors as a Novel Pharmacotherapy for Alcoholism$215,824
R21 · FY2023 · AA · contact PI
Targeting Metal-Dependent Epigenetic Modulators via MetalloPROTACs$205,385
R21 · FY2023 · CA
Metal-binding Isosteres for Influenza Endonuclease Inhibitors and Beyond$370,748
R01 · FY2022 · AI · contact PI
Metal-binding Isosteres for Influenza Endonuclease Inhibitors and Beyond$370,401
R01 · FY2021 · AI · contact PI
Metal-binding Isosteres for Influenza Endonuclease Inhibitors and Beyond$340,957
R01 · FY2020 · AI · contact PI
Developing Metallo-Beta-Lactamase Inhibitors$131,657
R01 · FY2019 · GM
Developing Metallo-Beta-Lactamase Inhibitors$527,911
R01 · FY2018 · GM
Metallofragments as 3-Dimensional Scaffolds for Fragment-Based Drug Discovery$182,073
R21 · FY2018 · AI · contact PI
Developing Metallo-Beta-Lactamase Inhibitors$529,229
R01 · FY2017 · GM
Role of CSN in the activity and dynamic cycling of cullin-RING ubiquitin ligases$327,728
R01 · FY2017 · CA
Insight and Optimization of Metalloprotein Inhibitors$272,145
R01 · FY2017 · GM · contact PI
Developing Metallo-Beta-Lactamase Inhibitors$528,645
R01 · FY2016 · GM
Role of CSN in the activity and dynamic cycling of cullin-RING ubiquitin ligases$327,728
R01 · FY2016 · CA
Insight and Optimization of Metalloprotein Inhibitors$274,539
R01 · FY2016 · GM · contact PI
Developing Metallo-Beta-Lactamase Inhibitors$585,218
R01 · FY2015 · GM
Role of CSN in the activity and dynamic cycling of cullin-RING ubiquitin ligases$327,728
R01 · FY2015 · CA
Insight and Optimization of Metalloprotein Inhibitors$276,680
R01 · FY2015 · GM · contact PI
Role of CSN in the activity and dynamic cycling of cullin-RING ubiquitin ligases$317,896
R01 · FY2014 · CA
Chelator Fragment Libraries for Optimizing Metal-Ligand Interactions in Metallopr$282,903
R01 · FY2014 · GM · contact PI
Role of CSN in the activity and dynamic cycling of cullin-RING ubiquitin ligases$344,353
R01 · FY2013 · CA
Chelator Fragment Libraries for Optimizing Metal-Ligand Interactions in Metallopr$273,001
R01 · FY2013 · GM · contact PI
Chelator Fragment Libraries for Optimizing Metal-Ligand Interactions in Metallopr$282,832
R01 · FY2012 · GM · contact PI
Chelator Fragment Libraries for Optimizing Metal-Ligand Interactions in Metallopr$282,059
R01 · FY2011 · GM · contact PI
Translational Development of Novel MMP Inhibitors$367,243
R01 · FY2010 · HL · contact PI
New Strategies and Screening Methods for Metalloproteinase Inhibition$186,101
R21 · FY2010 · HL · contact PI
Translational Development of Novel MMP Inhibitors$376,635
R01 · FY2009 · HL · contact PI
New Strategies and Screening Methods for Metalloproteinase Inhibition$186,557
R21 · FY2009 · HL · contact PI
Translational Development of Novel MMP Inhibitors$379,406
R01 · FY2008 · HL · contact PI
A Bioinorganic Approach to Anthrax Lethal Factor Inhibitors$75,782
R03 · FY2008 · AI · contact PI
Translational Development of Novel MMP Inhibitors$368,307
R01 · FY2007 · HL · contact PI
A Bioinorganic Approach to Anthrax Lethal Factor Inhibitors$77,250
R03 · FY2007 · AI · contact PI
Translational Development of Novel MMP Inhibitors$11,705
R01 · FY2007 · HL · contact PI
Translational Development of Novel MMP Inhibitors$379,172
R01 · FY2006 · HL · contact PI
INVESTIGATING CIS PLATIN INTERACTIONS WITH TELOMERE DNA$24,917
F32 · FY2000 · CA