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James F Markmann

Massachusetts General Hospital

$21,074,268
Attributed
$36,800,076
Total exposure
12
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $6.6M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$36,800,076 · 12

By mechanism

U01$17,862,951 · 2
R01$17,060,980 · 6
R56$794,600 · 2
P01$559,545 · 1
P30$522,000 · 1

Top collaborators

Most similar at Massachusetts General Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Transplantation

Research focus

TransplantationIn VivoAllograftingCellsAntibodiesProductionT-LymphocyteAntigensPathway InteractionsB-LymphocytesDesignInvestigationAutoimmunityReportingPreventBaseTransplantation ToleranceClinical ApplicationRegimenGraft SurvivalTechnologyGenerationsIn VitroFunding

Grant awards (57)

Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantation$4,303,502
U01 · FY2025 · AI
Immune repertoire remodeling following B cell-targeted CAR T cells for induction of renal allograft tolerance in non-human primates$1,648,086
R01 · FY2025 · AI
Mechanisms of action, optimization and application of Bregs$600,071
R01 · FY2025 · AI · contact PI
Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantation$3,825,129
U01 · FY2024 · AI
Liver Xenotransplantation using CRISPR-modified Porcine Organs$754,875
U01 · FY2024 · AI · contact PI
Mechanisms of action, optimization and application of Bregs$619,816
R01 · FY2024 · AI · contact PI
Hydrogels for human beta cell survival, function and evasion of immune rejection$82,702
R01 · FY2024 · DK
Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantation$764,364
U01 · FY2023 · AI
Liver Xenotransplantation using CRISPR-modified Porcine Organs$754,875
U01 · FY2023 · AI · contact PI
Mechanisms of action, optimization and application of Bregs$637,715
R01 · FY2023 · AI · contact PI
Hydrogels for human beta cell survival, function and evasion of immune rejection$82,702
R01 · FY2023 · DK
Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantation$2,975,228
U01 · FY2022 · AI
Hydrogels for human beta cell survival, function and evasion of immune rejection$822,338
R01 · FY2022 · DK
Liver Xenotransplantation using CRISPR-modified Porcine Organs$754,875
U01 · FY2022 · AI · contact PI
Mechanisms of B cell-Dependent Transplantation Tolerance$508,916
R01 · FY2022 · AI · contact PI
Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantation$2,975,228
U01 · FY2021 · AI
Liver Xenotransplantation using CRISPR-modified Porcine Organs$754,875
U01 · FY2021 · AI · contact PI
Mechanisms of B cell-Dependent Transplantation Tolerance$508,916
R01 · FY2021 · AI · contact PI
Liver Xenotransplantation using CRISPR-modified Porcine Organs$771,875
R01 · FY2020 · AI · contact PI
Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion$551,721
R01 · FY2020 · DK · contact PI
Mechanisms of B cell-Dependent Transplantation Tolerance$508,916
R01 · FY2020 · AI · contact PI
Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion$551,721
R01 · FY2019 · DK · contact PI
Mechanisms of B cell-Dependent Transplantation Tolerance$508,916
R01 · FY2019 · AI · contact PI
Human Islet Core$104,400
P30 · FY2019 · DK · contact PI
Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion$551,721
R01 · FY2018 · DK · contact PI
Mechanisms of B cell-Dependent Transplantation Tolerance$508,916
R01 · FY2018 · AI · contact PI
Human Islet Core$104,400
P30 · FY2018 · DK · contact PI
Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion$551,721
R01 · FY2017 · DK · contact PI
Human Islet Core$104,400
P30 · FY2017 · DK · contact PI
Expanding the Liver Transplant Organ Pool through Ex Vivo Liver Perfusion$551,721
R01 · FY2016 · DK · contact PI
Mechanisms of B Cell-Dependent Transplantation Tolerance$430,936
R01 · FY2016 · AI · contact PI
Human Islet Core$104,400
P30 · FY2016 · DK · contact PI
Mechanisms of B Cell-Dependent Transplantation Tolerance$430,936
R01 · FY2015 · AI · contact PI
Human Islet Core$104,400
P30 · FY2015 · DK · contact PI
Mechanisms of B Cell-Dependent Transplantation Tolerance$430,936
R01 · FY2014 · AI · contact PI
Mechanisms of B Cell-Dependent Transplantation Tolerance$405,080
R01 · FY2013 · AI · contact PI
Mechanisms of B Cell-Dependent Transplantation Tolerance$229,814
R01 · FY2012 · AI · contact PI
Mechanisms of B Cell-Dependent Transplantation Tolerance$354,000
R56 · FY2011 · AI · contact PI
Regulation and Counter-Regulation in Transplantation$440,600
R56 · FY2010 · AI · contact PI
Mechanism of anti-CD45 induced transplantation tolerance$382,157
R01 · FY2010 · AI · contact PI
Mechanism of anti-CD45 induced transplantation tolerance$385,716
R01 · FY2009 · AI · contact PI
Mechanism of anti-CD45 induced transplantation tolerance$385,099
R01 · FY2008 · AI · contact PI
Regulatory T cells in transplantation tolerance$372,066
R01 · FY2008 · AI · contact PI
Regulatory T cells in transplantation tolerance$207,002
R01 · FY2007 · AI · contact PI
Mechanism of anti-CD45 induced transplantation tolerance$198,124
R01 · FY2007 · AI · contact PI
Mechanism of anti-CD45 induced transplantation tolerance$185,697
R01 · FY2007 · AI · contact PI
Regulatory T cells in transplantation tolerance$36,010
R01 · FY2007 · AI · contact PI
Mechanism of anti-CD45 induced transplantation tolerance$405,193
R01 · FY2006 · AI · contact PI
Regulatory T cells in transplantation tolerance$358,376
R01 · FY2006 · AI · contact PI
Regulatory T cells in transplantation tolerance$367,000
R01 · FY2005 · AI
Regulatory T cells in transplantation tolerance$381,625
R01 · FY2004 · AI
Mechanisms of Acquired Central Transplantation Tolerance$300,620
R01 · FY2003 · AI
Mechanisms of Acquired Central Transplantation Tolerance$300,620
R01 · FY2002 · AI
Gene Transfer for Autoimmune Beta Cell Damage Prevention$186,515
P01 · FY2002 · DK
Mechanisms of Acquired Central Transplantation Tolerance$299,483
R01 · FY2001 · AI
Gene Transfer for Autoimmune Beta Cell Damage Prevention$186,515
P01 · FY2001 · DK
Gene Transfer for Autoimmune Beta Cell Damage Prevention$186,515
P01 · FY2000 · DK