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Christopher F Basler

Washington University

$44,557,002
Attributed
$47,729,460
Total exposure
31
Grants
26
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $9.7M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$73,057,678 · 33

By mechanism

U19$43,743,046 · 11
R01$16,744,920 · 5
P01$4,014,875 · 3
R21$3,497,628 · 8
U54$2,874,357 · 1
R56$1,972,416 · 3

Top collaborators

Most similar at Washington University

Same institution · by research overlap

Others in their field

Top investigators on “Proteins

Research focus

ProteinsViralEbola VirusFilovirusInterferonsInfectionPathogenResponseVirusBaseAntiviral AgentsVirus ReplicationViral Hemorrhagic FeversNational Institute Of Allergy And Infectious DiseaseFrankfurt-Marburg Syndrome VirusCellsSignal TransductionVirus DiseasesPathogenesisMutantViral ProteinsProductionImmuneCategories

Grant awards (115)

Contributions of Ebola and Marburg virus VP30 and VP24 proteins to viral RNA synthesis, assembly and egress$498,635
P01 · FY2025 · AI · contact PI
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus Infection$619,478
R01 · FY2024 · AI · contact PI
Contributions of Ebola and Marburg virus VP30 and VP24 proteins to viral RNA synthesis, assembly and egress$414,434
P01 · FY2024 · AI · contact PI
Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection$762,140
R01 · FY2023 · AI
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus Infection$619,478
R01 · FY2023 · AI · contact PI
Contributions of Ebola and Marburg virus VP30 and VP24 proteins to viral RNA synthesis, assembly and egress$436,375
P01 · FY2023 · AI · contact PI
Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection$61,201
R01 · FY2023 · AI
Inhibitors of SARS-CoV-2 Polymerase$4,353,162
U19 · FY2022 · AI · contact PI
Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection$774,291
R01 · FY2022 · AI
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus Infection$619,478
R01 · FY2022 · AI · contact PI
Understanding how the MERS Coronavirus protein ORF4b interactions with importin alpha modulate innate immunity$217,459
R21 · FY2022 · AI · contact PI
Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection$786,333
R01 · FY2021 · AI
Small Molecule Inhibitors of Ebola Virus Polymerase Function$770,311
R01 · FY2021 · AI · contact PI
VPS34 inhibitors as SARS-CoV-2 antivirals$415,889
R21 · FY2021 · AI · contact PI
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus Infection$407,579
R01 · FY2021 · AI · contact PI
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus Infection$194,263
R01 · FY2021 · AI · contact PI
Understanding how the MERS Coronavirus protein ORF4b interactions with importin alpha modulate innate immunity$186,654
R21 · FY2021 · AI · contact PI
Small Molecule Inhibitors of Ebola Virus Polymerase Function$180,913
R01 · FY2021 · AI · contact PI
VPS34 inhibitors as SARS-CoV-2 antivirals$13,111
R21 · FY2021 · AI · contact PI
Understanding how the MERS Coronavirus protein ORF4b interactions with importin alpha modulate innate immunity$5,392
R21 · FY2021 · AI · contact PI
Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection$796,422
R01 · FY2020 · AI
Small Molecule Inhibitors of Ebola Virus Polymerase Function$779,568
R01 · FY2020 · AI · contact PI
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus Infection$550,373
R01 · FY2020 · AI · contact PI
Cis and Trans-acting Factors that Modulate Ebola Virus RNA Synthesis$303,000
P01 · FY2020 · AI · contact PI
Structural Basis for Henipavirus Matrix Protein Nucleo-Cytoplasmic Trafficking$204,239
R21 · FY2020 · AI · contact PI
Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection$832,743
R01 · FY2019 · AI
Small Molecule Inhibitors of Ebola Virus Polymerase Function$779,570
R01 · FY2019 · AI · contact PI
Cis and Trans-acting Factors that Modulate Ebola Virus RNA Synthesis$303,001
P01 · FY2019 · AI · contact PI
Generation of A Safe Yet Fully Replication-Competent Filovirus$232,450
R21 · FY2019 · AI · contact PI
Structural Basis for Henipavirus Matrix Protein Nucleo-Cytoplasmic Trafficking$178,341
R21 · FY2019 · AI · contact PI
Therapeutics Targeting Filoviral interferon-antagonist and replication functions$2,953,996
U19 · FY2018 · AI · contact PI
Mechanisms of evasion of the innate and adaptive immune responses to filoviruses$1,858,977
U19 · FY2018 · AI · contact PI
Small Molecule Inhibitors of Ebola Virus Polymerase Function$872,936
R01 · FY2018 · AI · contact PI
SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT$774,428
U19 · FY2018 · AI · contact PI
Molecular mechanisms of immune dysregulation by filoviral interferon$700,685
U19 · FY2018 · AI · contact PI
Core-001$453,307
U19 · FY2018 · AI · contact PI
Administrative Core$325,356
U19 · FY2018 · AI · contact PI
Cis and Trans-acting Factors that Modulate Ebola Virus RNA Synthesis$303,000
P01 · FY2018 · AI · contact PI
Generation of A Safe Yet Fully Replication-Competent Filovirus$206,650
R21 · FY2018 · AI · contact PI
Admin-Core-001$112,302
U19 · FY2018 · AI · contact PI
Therapeutics Targeting Filoviral interferon-antagonist and replication functions$3,125,695
U19 · FY2017 · AI · contact PI
Mechanisms of evasion of the innate and adaptive immune responses to filoviruses$1,861,376
U19 · FY2017 · AI · contact PI
SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT$941,531
U19 · FY2017 · AI · contact PI
Small Molecule Inhibitors of Ebola Virus Polymerase Function$918,430
R01 · FY2017 · AI · contact PI
Molecular mechanisms of immune dysregulation by filoviral interferon$701,884
U19 · FY2017 · AI · contact PI
DEVELOPMENT, VALIDATION, AND OPTIMIZATION OF HTS SCREENS TARGETING NIPAH AND HENDRA VIRUS RNA SYNTHESIS$533,763
R56 · FY2017 · AI
Core-001$454,297
U19 · FY2017 · AI · contact PI
High-throughput screen for inhibitors of Marburg virus VP24-Keap 1$391,953
R01 · FY2017 · AI · contact PI
Administrative Core$325,956
U19 · FY2017 · AI · contact PI
Cis and Trans-acting Factors that Modulate Ebola Virus RNA Synthesis$303,000
P01 · FY2017 · AI · contact PI
Admin-Core-001$111,942
U19 · FY2017 · AI · contact PI
Therapeutics Targeting Filoviral interferon-antagonist and replication functions$3,335,737
U19 · FY2016 · AI · contact PI
Mechanisms of evasion of the innate and adaptive immune responses to filoviruses$1,904,609
U19 · FY2016 · AI · contact PI
SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT$957,719
U19 · FY2016 · AI · contact PI
SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT$822,509
U19 · FY2016 · AI · contact PI
Molecular mechanisms of immune dysregulation by filoviral interferon$683,848
U19 · FY2016 · AI · contact PI
Molecular mechanisms of immune dysregulation by filoviral interferon$671,068
U19 · FY2016 · AI · contact PI
High-throughput screen for inhibitors of Marburg virus VP24-Keap 1$392,625
R01 · FY2016 · AI · contact PI
Cis and Trans-acting Factors that Modulate Ebola Virus RNA Synthesis$352,640
P01 · FY2016 · AI · contact PI
ADMINISTRATIVE CORE$201,952
U19 · FY2016 · AI · contact PI
Administrative Core$92,442
U19 · FY2016 · AI · contact PI
ADMINISTRATIVE CORE$81,050
U19 · FY2016 · AI · contact PI
Administrative Core$80,490
U19 · FY2016 · AI · contact PI
Therapeutics Targeting Filoviral interferon-antagonist and replication functions$3,157,337
U19 · FY2015 · AI · contact PI
Mechanisms of evasion of the innate and adaptive immune responses to filoviruses$1,918,723
U19 · FY2015 · AI · contact PI
SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT$694,615
U19 · FY2015 · AI · contact PI
Molecular mechanisms of immune dysregulation by filoviral interferon$676,712
U19 · FY2015 · AI · contact PI
Ebola virus VP24_a novel inhibitor of interferon and oxidative stress signaling$432,835
R01 · FY2015 · AI · contact PI
High-throughput screen for inhibitors of Marburg virus VP24-Keap1$422,253
R01 · FY2015 · AI · contact PI
ADMINISTRATIVE CORE$132,340
U19 · FY2015 · AI · contact PI
Administrative Core$93,233
U19 · FY2015 · AI · contact PI
Therapeutics Targeting Filoviral interferon-antagonist and replication functions$3,211,769
U19 · FY2014 · AI · contact PI
Mechanisms of evasion of the innate and adaptive immune responses to filoviruses$1,999,999
U19 · FY2014 · AI · contact PI
Molecular mechanisms of immune dysregulation by filoviral interferon$730,183
U19 · FY2014 · AI · contact PI
SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT$711,891
U19 · FY2014 · AI · contact PI
Ebola virus VP24_a novel inhibitor of interferon and oxidative stress signaling$497,760
R01 · FY2014 · AI · contact PI
Naturally occurring human antibodies to alphavirus infection$199,239
R21 · FY2014 · AI · contact PI
ADMINISTRATIVE CORE$111,527
U19 · FY2014 · AI · contact PI
Administrative Core$101,382
U19 · FY2014 · AI · contact PI
Ebola virus VP24_a novel inhibitor of interferon and oxidative stress signaling$499,096
R01 · FY2013 · AI · contact PI
Naturally occurring human antibodies to alphavirus infection$261,074
R21 · FY2013 · AI · contact PI
p38 MAP kinase inhibitors as therapeutics targeting ebolavirus entry$191,055
R21 · FY2013 · AI · contact PI
Ebola virus VP24_a novel inhibitor of interferon and oxidative stress signaling$437,614
R01 · FY2012 · AI · contact PI
Filovirus inhibitors of interferon signaling: virulence factors and drug targets$374,578
U54 · FY2012 · AI · contact PI
p38 MAP kinase inhibitors as therapeutics targeting ebolavirus entry$266,117
R21 · FY2012 · AI · contact PI
Ebola virus VP24_a novel inhibitor of interferon and oxidative stress signaling$33,844
R01 · FY2012 · AI · contact PI
Development of pan-filoviral inhibitors of replication targeting VP35 proteins$761,178
R56 · FY2011 · AI · contact PI
Ebola virus VP24_a novel inhibitor of interferon and oxidative stress signaling$460,327
R01 · FY2011 · AI · contact PI
Filovirus inhibitors of interferon signaling: virulence factors and drug targets$449,592
U54 · FY2011 · AI · contact PI
1918 Influenza Virus-Neutralizing Antibodies from Individuals Born 1960-1990$251,708
R21 · FY2011 · AI · contact PI
Filovirus inhibitors of interferon signaling: virulence factors and drug targets$1,104,197
U54 · FY2010 · AI · contact PI
Pan-filovirus antivirals targeting the VP35 protein$677,475
R56 · FY2010 · AI · contact PI
1918 Influenza Virus-Neutralizing Antibodies from Individuals Born 1960-1990$211,875
R21 · FY2010 · AI · contact PI
Filovirus inhibitors of interferon signaling: virulence factors and drug targets$945,990
U54 · FY2009 · AI · contact PI
Ebola VP35 Interferon-Antagonist: Mechanism and Signif$448,959
R01 · FY2009 · AI · contact PI
Ebola VP35 Interferon-Antagonist: Mechanism and Signif$10,565
R01 · FY2009 · AI · contact PI
Modulation of Dendritic Cell Function by Ebola Virus$457,746
U19 · FY2008 · AI · contact PI
Ebola VP35 Interferon-Antagonist: Mechanism and Signif$345,672
R01 · FY2008 · AI · contact PI
The 1918 HA and NA: Antigens and Virulence Factors$213,294
P01 · FY2008 · AI · contact PI
Modulation of Dendritic Cell Function by Ebola Virus$457,954
U19 · FY2007 · AI · contact PI
Ebola VP35 Interferon-Antagonist: Mechanism and Signif$352,368
R01 · FY2007 · AI · contact PI
The 1918 HA and NA: Antigens and Virulence Factors$211,932
P01 · FY2007 · AI · contact PI
Modulation of Dendritic Cell Function by Ebola Virus$475,043
U19 · FY2006 · AI · contact PI
Ebola VP35 Interferon-Antagonist: Mechanism and Signif$362,892
R01 · FY2006 · AI · contact PI
The 1918 HA and NA: Antigens and Virulence Factors$217,918
P01 · FY2006 · AI · contact PI
Modulation of Dendritic Cell Function by Ebola Virus$467,034
U19 · FY2005 · AI
Ebola VP35 Interferon-Antagonist: Mechanism and Signif$330,650
R01 · FY2005 · AI
The 1918 HA and NA: Antigens and Virulence Factors$212,341
P01 · FY2005 · AI
Modulation of Dendritic Cell Function by Ebola Virus$459,240
U19 · FY2004 · AI
The 1918 HA and NA: Antigens and Virulence Factors$245,305
P01 · FY2004 · AI
EBOLA VIRUS INTERFERON-ANTAGONISTS AND VIRULENCE$219,500
R21 · FY2003 · AI
Lassa and Nipah Virus Interferon-Antagonists$84,750
R03 · FY2003 · AI
EBOLA VIRUS INTERFERON-ANTAGONISTS AND VIRULENCE$236,875
R21 · FY2002 · AI
Lassa and Nipah Virus Interferon-Antagonists$84,750
R03 · FY2002 · AI
CELLULAR RNA HELICASE IN INFLUENZA VIRUS REPLICATION$40,936
F32 · FY2000 · AI