← Leaderboards
David H Sherman
Colorado State University
$25,887,943
Attributed
$35,975,315
Total exposure
18
Grants
9
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $3.5M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$40,579,964 · 19
By mechanism
R01$26,015,766 · 10
P01$4,782,608 · 2
U01$4,235,935 · 1
R35$3,299,324 · 1
T32$1,317,445 · 1
R21$444,824 · 1
Top collaborators
- Janet L Smith13 shared
- Kathleen L Collins8 shared
- William H Gerwick5 shared
- Robert Michael Williams5 shared
- Chaoping Chen4 shared
- Thomas D Y Chung4 shared
- John Montgomery4 shared
- Larissa M. Podust4 shared
Others in their field
Top investigators on “Pathway Interactions”
- David Heimbrook · Leidos Biomedical Research, Inc.$202,777,247
- Ralph Parchment · Leidos Biomedical Research, Inc.$146,974,543
- David R. Weir · University Of Michigan At Ann Arbor$129,316,139
- Daniel Ernest Ford · Johns Hopkins University$108,075,637
- David W Simpson · University Of Southern California$88,046,235
- Charles D. Blanke · Oregon Health And Science University$86,571,896
Research focus
Pathway InteractionsStructureEnzymesBaseDesignProgramsComplexBiochemicalLeadPolyketide SynthaseProteinsAnalogMolecularPharmacologic SubstancePropertyBiologicalEngineeringBiological FactorsSeriesNatural ProductsTherapeutic AgentsKineticsReactionSubstrate Specificity
Grant awards (93)
Next-Generation CMA/CMB Derivatives as Targeted Inhibitors of HIV Nef$3,110,884
R01 · FY2025 · AI
Discovery and Characterization of Natural Product Systems$381,095
R35 · FY2025 · GM · contact PI
Discovery and Characterization of Natural Product Systems$381,095
R35 · FY2024 · GM · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$686,433
R01 · FY2023 · AI · contact PI
HTS Targeting HIV-1 Protease Autoprocessing for First in Class Drug Discovery$510,656
R01 · FY2023 · AI
Discovery and Characterization of Natural Product Systems$381,095
R35 · FY2023 · GM · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$80,346
R01 · FY2023 · AI · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$80,346
R01 · FY2023 · AI · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$700,841
R01 · FY2022 · AI · contact PI
HTS Targeting HIV-1 Protease Autoprocessing for First in Class Drug Discovery$640,952
R01 · FY2022 · AI
Discovery and Characterization of Natural Product Systems$381,095
R35 · FY2022 · GM · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$698,581
R01 · FY2021 · AI · contact PI
HTS Targeting HIV-1 Protease Autoprocessing for First in Class Drug Discovery$636,059
R01 · FY2021 · AI
Discovery and Characterization of Natural Product Systems$393,437
R35 · FY2021 · GM · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$844,572
R01 · FY2020 · AI · contact PI
HTS Targeting HIV-1 Protease Autoprocessing for First in Class Drug Discovery$803,950
R01 · FY2020 · AI
Discovery and Characterization of Natural Product Systems$431,308
R35 · FY2020 · GM · contact PI
Development of natural product inhibitors of Nef for clearance of HIV reservoirs$739,671
R01 · FY2019 · AI · contact PI
Discovery and Characterization of Natural Product Systems$355,593
R35 · FY2019 · GM · contact PI
Discovery and Characterization of Natural Product Systems-Research Supplement to Promote Diversity$75,715
R35 · FY2019 · GM · contact PI
Molecular Analysis of Modular Polyketide Synthases$388,963
R01 · FY2018 · GM · contact PI
Total Synthesis and Biosynthesis of Bioactive Substances$256,101
R01 · FY2018 · CA
An in vitro Microscale Platform for Antibiotic Biosynthesis and Discovery$195,519
R21 · FY2018 · AI
Discovery and Characterization of Natural Product Systems$183,019
R35 · FY2018 · GM · contact PI
Molecular Analysis of Modular Polyketide Synthases$388,963
R01 · FY2017 · GM · contact PI
Total Synthesis and Biosynthesis of Bioactive Substances$256,101
R01 · FY2017 · CA
An in vitro Microscale Platform for Antibiotic Biosynthesis and Discovery$249,305
R21 · FY2017 · AI
Discovery and Characterization of Natural Product Systems$167,335
R35 · FY2017 · GM · contact PI
Molecular Analysis of Modular Polyketide Synthases$386,249
R01 · FY2016 · GM · contact PI
Total Synthesis and Biosynthesis of Bioactive Substances$256,101
R01 · FY2016 · CA
Discovery and Characterization of Natural Product Systems$168,537
R35 · FY2016 · GM · contact PI
Structure and Engineering of Natural Product Cyctochrome P450 Enzymes$407,618
R01 · FY2015 · GM · contact PI
Molecular Analysis of Modular Polyketide Synthases$386,249
R01 · FY2015 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$327,742
R01 · FY2015 · CA · contact PI
Total Synthesis and Biosynthesis of Bioactive Substances$256,120
R01 · FY2015 · CA
Molecular Analysis of Modular Polyketide Synthases$501,609
R01 · FY2014 · GM · contact PI
Structure and Engineering of Natural Product Cyctochrome P450 Enzymes$416,446
R01 · FY2014 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$325,086
R01 · FY2014 · CA · contact PI
Total Synthesis and Biosynthesis of Bioactive Substances$268,515
R01 · FY2014 · CA
Discovery of Natural Product based Drugs and Bioenergetic Materials from CR$806,645
U01 · FY2013 · TW · contact PI
Molecular Analysis of Modular Polyketide Synthases$487,950
R01 · FY2013 · GM · contact PI
Structure and Engineering of Natural Product Cyctochrome P450 Enzymes$410,081
R01 · FY2013 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$322,152
R01 · FY2013 · CA · contact PI
Discovery of Natural Product based Drugs and Bioenergetic Materials from CR$849,100
U01 · FY2012 · TW · contact PI
Molecular Analysis of Modular Polyketide Synthases$506,779
R01 · FY2012 · GM · contact PI
Structure and Engineering of Natural Product Cyctochrome P450 Enzymes$447,031
R01 · FY2012 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$350,448
R01 · FY2012 · CA · contact PI
Discovery of Natural Product based Drugs and Bioenergetic Materials from CR$749,100
U01 · FY2011 · TW · contact PI
Molecular Analysis of Modular Polyketide Synthases$507,173
R01 · FY2011 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$357,809
R01 · FY2011 · CA · contact PI
LIPOPOLYSACCHARIDE TRANSPORT$4,222
P41 · FY2011 · RR · contact PI
Discovery of Natural Product based Drugs and Bioenergetic Materials from CR$954,100
U01 · FY2010 · TW · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$345,655
R01 · FY2010 · CA · contact PI
Structure and Engineering of Natural Product Cytochrome P450 Enzymes$293,190
R01 · FY2010 · GM · contact PI
of Natural Product based Drugs and Bioenergetic Materials from Costa Rican Biota$876,990
U01 · FY2009 · TW · contact PI
Molecular Analysis of Modular Polyketide Synthases$405,836
R01 · FY2009 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$338,896
R01 · FY2009 · CA · contact PI
A chemoenzymatic technology for the efficient synthesis of novel cryptophycins$322,693
R41 · FY2009 · CA · contact PI
Structure and Engineering of Natural Product Cytochrome P450 Enzymes$296,151
R01 · FY2009 · GM · contact PI
Molecular Analysis of Modular Polyketide Synthases$394,147
R01 · FY2008 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$329,059
R01 · FY2008 · CA · contact PI
Structure and Engineering of Natural Product Cytochrome P450 Enzymes$296,064
R01 · FY2008 · GM · contact PI
Development of New Therapeutics Against Bacillus Anthracis$157,147
U54 · FY2008 · AI · contact PI
Molecular Analysis of Modular Polyketide Synthases$394,226
R01 · FY2007 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$325,832
R01 · FY2007 · CA · contact PI
Structure and Engineering of Natural Product Cytochrome P450 Enzymes$302,482
R01 · FY2007 · GM · contact PI
Molecular Analysis of Modular Polyketide Synthases$408,058
R01 · FY2006 · GM · contact PI
Biosynthetic Analysis of Marine Cyanobacterial Pathways$362,889
R01 · FY2006 · CA · contact PI
Genomic Analysis of Antibiotic Biosynthesis$289,166
R01 · FY2005 · GM
Genomic Analysis of Antibiotic Biosynthesis$289,631
R01 · FY2004 · GM
COMBINATORIAL CREATION OF NEW ANTICANCER AGENTS$884,259
P01 · FY2003 · CA
COMBINATORIAL CREATION OF NEW ANTICANCER AGENTS$422,655
P01 · FY2003 · CA
BIOCHEMISTRY AND MOLECULAR GENETICS OF MITOMYCIN BIOSYNT$353,054
R01 · FY2003 · CA
Genomic Analysis of Antibiotic Biosynthesis$203,051
R01 · FY2003 · GM
Genomic Analysis of Antibiotic Biosynthesis$85,188
R01 · FY2003 · GM
COMBINATORIAL CREATION OF NEW ANTICANCER AGENTS$1,188,073
P01 · FY2002 · CA
TRAINING FOR FUTURE BIOTECHNOLOGY DEVELOPMENT$468,824
T32 · FY2002 · GM
BIOCHEMISTRY AND MOLECULAR GENETICS OF MITOMYCIN BIOSYNT$296,548
R01 · FY2002 · CA
Genomic Analysis of Antibiotic Biosynthesis$289,560
R01 · FY2002 · GM
COMBINATORIAL BIOSYNTHESIS AND THE PIKROMYCIN PATHWAY$265,971
R01 · FY2002 · GM
COMBINATORIAL BIOSYNTHESIS AND THE PIKROMYCIN PATHWAY$157,843
R01 · FY2002 · GM
Generation of diverse natural products by combinatorial technologies$0
P01 · FY2002 · CA
COMBINATORIAL CREATION OF NEW ANTICANCER AGENTS$1,070,422
P01 · FY2001 · CA
TRAINING FOR FUTURE BIOTECHNOLOGY DEVELOPMENT$436,752
T32 · FY2001 · GM
COMBINATORIAL BIOSYNTHESIS AND THE PIKROMYCIN PATHWAY$392,588
R01 · FY2001 · GM
BIOCHEMISTRY AND MOLECULAR GENETICS OF MITOMYCIN BIOSYNT$287,909
R01 · FY2001 · CA
Generation of diverse natural products by combinatorial technologies$0
P01 · FY2001 · CA
COMBINATORIAL CREATION OF NEW ANTICANCER AGENTS$1,039,240
P01 · FY2000 · CA
TRAINING FOR FUTURE BIOTECHNOLOGY DEVELOPMENT$411,869
T32 · FY2000 · GM
COMBINATORIAL BIOSYNTHESIS AND THE PIKROMYCIN PATHWAY$381,323
R01 · FY2000 · GM
BIOCHEMISTRY AND MOLECULAR GENETICS OF MITOMYCIN BIOSYNT$302,523
R01 · FY2000 · CA
METABOLIC ENGINEERING OF CEPHAMYCIN C BIOSYNTHESIS$184,349
R01 · FY2000 · GM
Generation of diverse natural products by combinatorial technologies$177,959
P01 · FY2000 · CA