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John Karanicolas

Research Inst Of Fox Chase Can Ctr

$6,668,157
Attributed
$6,668,157
Total exposure
8
Grants
7
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $962.1K · FY201124
$1M$750K$500K$250K$0
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24

Funding mix

By agency

NIH$6,668,157 · 8

By mechanism

R01$5,760,940 · 4
U54$804,398 · 2
P30$87,394 · 1
P41$15,425 · 1

Top collaborators

No co-investigators on record.

Most similar at Research Inst Of Fox Chase Can Ctr

Same institution · by research overlap

Others in their field

Top investigators on “Malignant Neoplasms

Research focus

Malignant NeoplasmsProteinsBiochemicalStructureLibrariesComplexMolecular ConformationIn VitroDesignScreeningBindingBaseComputer SimulationMembrane ProteinsScaffoldComputing MethodologiesResearch PersonnelInhibitor/AntagonistMutationCellsComplementSmall MoleculeInterestShapes

Grant awards (23)

Refolding Mutant p53: A Strategy for Cancer Prevention in Li-Fraumeni Syndrome$391,886
U54 · FY2024 · CA · contact PI
Designing selective kinase inhibitors via deep learning$549,557
R01 · FY2023 · GM · contact PI
Designing selective kinase inhibitors via deep learning$181,277
R01 · FY2023 · GM · contact PI
Designing selective kinase inhibitors via deep learning$549,557
R01 · FY2022 · GM · contact PI
Refolding Mutant p53: A Strategy for Cancer Prevention in Li-Fraumeni Syndrome$412,512
U54 · FY2022 · CA · contact PI
Robust rational design of chemical tools to inhibit RNA-binding proteins$357,960
R01 · FY2020 · GM · contact PI
Robust Rational Design of Chemical Tools to Inhibit RNA-binding Proteins$39,187
R01 · FY2020 · GM · contact PI
Robust rational design of chemical tools to inhibit RNA-binding proteins$357,960
R01 · FY2019 · GM · contact PI
Identifying stabilizers of p53 using pocket complementarity$348,793
R01 · FY2019 · GM · contact PI
Robust rational design of chemical tools to inhibit RNA-binding proteins$356,141
R01 · FY2018 · GM · contact PI
Identifying stabilizers of p53 using pocket complementarity$345,871
R01 · FY2018 · GM · contact PI
Identifying stabilizers of p53 using pocket complementarity$200,000
R01 · FY2018 · GM · contact PI
Robust rational design of chemical tools to inhibit RNA-binding proteins$356,141
R01 · FY2017 · GM · contact PI
Identifying stabilizers of p53 using pocket complementarity$350,136
R01 · FY2017 · GM · contact PI
Identifying stabilizers of p53 using pocket complementarity$348,458
R01 · FY2016 · GM · contact PI
Identifying inhibitors of protein interactions using pocket optimization$252,287
R01 · FY2016 · GM · contact PI
Identifying inhibitors of protein interactions using pocket optimization$69,637
R01 · FY2016 · GM · contact PI
Identifying inhibitors of protein interactions using pocket optimization$277,075
R01 · FY2015 · GM · contact PI
Identifying inhibitors of protein interactions using pocket optimization$277,449
R01 · FY2014 · GM · contact PI
Identifying inhibitors of protein interactions using pocket optimization$267,408
R01 · FY2013 · GM · contact PI
Identifying inhibitors of protein interactions using pocket optimization$276,046
R01 · FY2012 · GM · contact PI
IDENTIFYING MC1-1 INHIBITORS USING POCKET SHAPE OPTIMIZATION$87,394
P30 · FY2011 · RR · contact PI
SIMPLIFIED MODELS FOR PROTEIN FOLDING KINETICS &THERMODYNAMICS &MECHANISM$15,425
P41 · FY2004 · RR