GGrantIndex
← Leaderboards

Lawrence P Kane

University Of Pittsburgh At Pittsburgh

Google Scholar ↗PubMed ↗ORCID ↗
$11,819,892
Attributed
$15,357,190
Total exposure
14
Grants
13
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.3M · FY2006–25
$2M$1.5M$1M$500K$0
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$15,357,190 · 14

By mechanism

R01$12,879,185 · 6
R21$829,665 · 2
S10$754,920 · 1
R56$453,449 · 1
R03$439,971 · 3
P60$0 · 1

Top collaborators

Most similar at University Of Pittsburgh At Pittsburgh

Same institution · by research overlap

Others in their field

Top investigators on “Mediating”

Research focus

MediatingT-LymphocyteCellsProteinsT-Cell ActivationSignal TransductionMalignant NeoplasmsSignal PathwayImmune ResponsePathway InteractionsTumorRegulationLeadPlayImmuneBaseComplexCell TypeImmune SystemLigandsTranscription FactorResponseIn VivoPathogen

Grant awards (50)

Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$541,414
R01 · FY2025 · CA · contact PI
Novel TCR transgenic mice to study tumor neoantigen-specific T cell responses$66,992
R03 · FY2025 · CA · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$514,343
R01 · FY2024 · CA · contact PI
Novel TCR transgenic mice to study tumor neoantigen-specific T cell responses$66,992
R03 · FY2024 · CA · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$541,414
R01 · FY2023 · CA · contact PI
Regulation of PI3K by PIK3IP1/TrIP$327,269
R01 · FY2023 · GM · contact PI
Bigfoot Spectral Cell Sorter$754,920
S10 · FY2022 · OD · contact PI
Regulation of PI3K by PIK3IP1/TrIP$325,803
R01 · FY2022 · GM · contact PI
Regulation of T cell activation and exhaustion by Tim-3$388,425
R01 · FY2021 · AI · contact PI
Regulation of PI3K by PIK3IP1/TrIP$323,749
R01 · FY2021 · GM · contact PI
Regulation of T cell activation and exhaustion by Tim-3$73,932
R01 · FY2021 · AI · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$499,975
R01 · FY2020 · CA
Regulation of T cell activation and exhaustion by Tim-3$388,425
R01 · FY2020 · AI · contact PI
Regulation of PI3K by PIK3IP1/TrIP$336,220
R01 · FY2020 · GM · contact PI
Regulation of T cell activation and exhaustion by Tim-3$71,888
R01 · FY2020 · AI · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$484,976
R01 · FY2019 · CA
Regulation of T cell activation and exhaustion by Tim-3$388,425
R01 · FY2019 · AI · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$499,177
R01 · FY2018 · CA
Regulation of T cell activation and exhaustion by Tim-3$388,425
R01 · FY2018 · AI · contact PI
Negative Regulation of Mast Cell Activation by PIK3IP1$232,197
R21 · FY2018 · AI · contact PI
Novel mouse models for studying Tim-3 signaling$76,758
R03 · FY2018 · AI · contact PI
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell Activation$554,318
R01 · FY2017 · AI · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$495,583
R01 · FY2017 · CA
Negative Regulation of Mast Cell Activation by PIK3IP1$191,642
R21 · FY2017 · AI · contact PI
Novel mouse models for studying Tim-3 signaling$77,113
R03 · FY2017 · AI · contact PI
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell Activation$614,805
R01 · FY2016 · AI · contact PI
Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes$491,988
R01 · FY2016 · CA
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell Activation$636,418
R01 · FY2015 · AI · contact PI
Intrinsic Effects of Tim-3 on T cell exhaustion and TCR signaling$75,491
R03 · FY2015 · AI · contact PI
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell Activation$633,824
R01 · FY2014 · AI · contact PI
Intrinsic Effects of Tim-3 on T cell exhaustion and TCR signaling$76,625
R03 · FY2014 · AI · contact PI
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell Activation$16,409
R01 · FY2014 · AI · contact PI
Biochemical and Spatial Regulation of IKKg/NEMO During T Cell Activation$549,952
R01 · FY2013 · AI · contact PI
Regulation of T Cell Activation and Development by PIK3IP1$215,201
R21 · FY2013 · AI · contact PI
Signaling and Cell Biology of TIM-1$200,000
R56 · FY2013 · AI · contact PI
Regulation of T Cell Activation and Development by PIK3IP1$190,625
R21 · FY2012 · AI · contact PI
Regulation of T Cell Activation and Differentiation by TIM-1$280,546
R01 · FY2011 · AI · contact PI
Regulation of T Cell Activation and Differentiation by TIM-1$283,380
R01 · FY2010 · AI · contact PI
Regulation of NF-kB by the Akt kinase$235,285
R01 · FY2010 · GM · contact PI
Regulation of NF-kB by the Akt kinase$355,013
R01 · FY2009 · GM · contact PI
Regulation of T Cell Activation and Differentiation by TIM-1$286,242
R01 · FY2009 · AI · contact PI
Regulation of NF-kB by the Akt kinase$237,662
R01 · FY2009 · GM · contact PI
Regulation of T Cell Activation and Differentiation by TIM-1$157,775
R01 · FY2009 · AI · contact PI
Regulation of T Cell Activation and Differentiation by TIM-1$286,242
R01 · FY2008 · AI · contact PI
Regulation of NF-kB by the Akt kinase$233,891
R01 · FY2008 · GM · contact PI
Regulation of NF-kB by the Akt kinase$233,138
R01 · FY2007 · GM · contact PI
Regulation of T Cell Activation and Differentiation by TIM-1$202,854
R01 · FY2007 · AI · contact PI
Regulation of T Cell Activation and Differentiatin by TIM-1$253,449
R56 · FY2006 · AI · contact PI
AKT KINASE IN CO-STIMULATION OF T CELL ACTIVATION BY CD28$0
P60 · FY2002 · AR
AKT KINASE IN CO-STIMULATION OF T CELL ACTIVATION BY CD28$0
P60 · FY2001 · AR