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Russell L Margolis

Johns Hopkins University

$10,931,342
Attributed
$11,606,412
Total exposure
19
Grants
16
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $927.9K · FY200624
$1M$750K$500K$250K$0
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24

Funding mix

By agency

NIH$11,606,412 · 19

By mechanism

R21$5,689,993 · 13
R01$4,194,749 · 2
T32$755,025 · 1
P01$498,448 · 1
P50$468,197 · 1
M01$0 · 1

Top collaborators

Most similar at Johns Hopkins University

Same institution · by research overlap

Others in their field

Top investigators on “Pathogenesis

Research focus

PathogenesisHuntington DiseaseBrainGenesBaseCellsNeurodegenerative DisordersLeadTranscriptLengthToxic EffectResearch StudyMutationCag RepeatPropertyCell ModelMouse ModelExonsPathway InteractionsCell LineProteinsMutantProgramsNew Therapeutic Target

Grant awards (45)

Interdisciplinary Training in Psychiatry and Neuroscience$349,509
T32 · FY2024 · MH · contact PI
Interdisciplinary Training in Psychiatry and Neuroscience$405,516
T32 · FY2023 · MH · contact PI
Diffeomorphometry applied to functional connectivity in schizophrenia using ultrahigh resolution MRI$245,027
R21 · FY2023 · MH · contact PI
Diffeomorphometry applied to functional connectivity in schizophrenia using ultrahigh resolution MRI$220,187
R21 · FY2022 · MH · contact PI
Endogenous regulation of huntingtin expression as a therapeutic target for Huntington's disease$470,932
R01 · FY2021 · NS · contact PI
Comparison of HD and HDL2 mouse models to reveal common mechanisms of pathogenesis$450,313
R21 · FY2021 · NS · contact PI
Endogenous regulation of huntingtin expression as a therapeutic target for Huntington's disease$470,932
R01 · FY2020 · NS · contact PI
Junctophilin-3, calcium homeostasis, and neuronal dysfunction in HDL2$457,000
R21 · FY2020 · NS · contact PI
Endogenous regulation of huntingtin expression as a therapeutic target for Huntington's disease$470,932
R01 · FY2019 · NS · contact PI
Endogenous regulation of huntingtin expression as a therapeutic target for Huntington's disease$470,932
R01 · FY2018 · NS · contact PI
Endogenous regulation of huntingtin expression as a therapeutic target for Huntington's disease$470,333
R01 · FY2017 · NS · contact PI
Thalamic connectivity in recent onset schizophrenia measured by 7T fMRI$202,285
R21 · FY2017 · MH · contact PI
Thalamic connectivity in recent onset schizophrenia measured by 7T fMRI$258,196
R21 · FY2016 · MH · contact PI
Spinocerebellar ataxia type 12 iPSCs and PP2A dysregulation$243,000
R21 · FY2016 · NS · contact PI
Spinocerebellar ataxia type 12 iPSCs and PP2A dysregulation$202,500
R21 · FY2015 · NS · contact PI
Small molecule screen to suppress expression of mutant huntington$202,500
R21 · FY2015 · NS · contact PI
Small molecule screen to suppress expression of mutant huntington$243,000
R21 · FY2014 · NS · contact PI
iPS Cells for Investigation of HDL2 and HD Pathogenesis$200,475
R21 · FY2014 · NS · contact PI
iPS Cells for Investigation of HDL2 and HD Pathogenesis$243,000
R21 · FY2013 · NS · contact PI
Transcriptome in Huntington's disease and Huntington's disease-like 2$150,846
R21 · FY2013 · NS
Transcriptome in Huntington's disease and Huntington's disease-like 2$281,814
R21 · FY2012 · NS
Huntington's Disease Antisense Transcript$241,080
R21 · FY2011 · NS · contact PI
Neurons from pluripotent stem cells derived from schizophrenia patient fibroblast$246,000
R21 · FY2010 · MH · contact PI
Cell Models of RNA Neurotoxicity$213,098
R21 · FY2010 · NS · contact PI
Huntington's Disease Antisense Transcript$205,000
R21 · FY2010 · NS · contact PI
Genetics Core$162,320
P50 · FY2010 · NS · contact PI
A Novel Array For Detection of Unstable Tandem Repeats$221,400
R21 · FY2009 · MH · contact PI
Neurons from pluripotent stem cells derived from schizophrenia patient fibroblast$205,000
R21 · FY2009 · MH · contact PI
Cell Models of RNA Neurotoxicity$179,375
R21 · FY2009 · NS · contact PI
Genetics Core$152,947
P50 · FY2009 · NS · contact PI
A Mouse Model of RNA-induced Neurotoxcity$215,250
R21 · FY2008 · NS · contact PI
A Novel Array For Detection of Unstable Tandem Repeats$184,500
R21 · FY2008 · MH · contact PI
Genetics Core$152,930
P50 · FY2008 · NS · contact PI
A Mouse Model of RNA-induced Neurotoxcity$179,147
R21 · FY2007 · NS · contact PI
Genetics Core$173,240
P01 · FY2007 · NS · contact PI
Genetics Core$152,797
P01 · FY2006 · NS · contact PI
TRINUCLEOTIDE REPEATS AND NEUROLOGIC DISEASE$367,875
R01 · FY2004 · NS
TRINUCLEOTIDE REPEATS AND NEUROLOGIC DISEASE$367,875
R01 · FY2003 · NS
TRINUCLEOTIDE REPEATS AND NEUROLOGIC DISEASE$367,875
R01 · FY2002 · NS
PSYCHIATRIC SYMPTOMS IN NEURODEGENERATIVE DISORDERS$0
M01 · FY2002 · RR
TRINUCLEOTIDE REPEATS AND NEUROLOGIC DISEASE$368,063
R01 · FY2001 · NS
CORE--GENETICS$172,411
P01 · FY2001 · NS
PSYCHIATRIC SYMPTOMS IN NEURODEGENERATIVE DISORDERS$0
M01 · FY2001 · RR
TRINUCLEOTIDE REPEATS AND NEUROLOGIC DISEASE$369,000
R01 · FY2000 · NS
PSYCHIATRIC SYMPTOMS IN NEURODEGENERATIVE DISORDERS$0
M01 · FY2000 · RR