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Christopher Eldridge Sims

Altis Biosystems, Inc.

$7,131,837
Attributed
$10,144,099
Total exposure
12
Grants
9
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2.5M · FY201925
$5M$3.8M$2.5M$1.3M$0
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$10,144,099 · 12

By mechanism

R44$8,524,725 · 6
R43$1,619,374 · 6

Top collaborators

Most similar at Altis Biosystems, Inc.

Same institution · by research overlap

Others in their field

Other Emerging Leaders on “Intestines

Research focus

IntestinesCellsPharmacologic SubstanceStem CellsMonolayerReproducibilityPhysiologyGastrointestinalCell TypeIn VitroTissuesPharmaceutical PreparationsIntestinal EpitheliumScreeningScientistBiological ModelsBiotechnologyColonIn VivoBaseHigh Throughput ScreeningIn Vitro ModelOrganoidsPrograms

Grant awards (16)

Mucus and ALI Models of the Human Intestine$835,939
R44 · FY2025 · DK · contact PI
Planar culture of gastrointestinal stem cells for screening pharmaceuticals for adverse event risk$913,659
R44 · FY2024 · TR · contact PI
InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammation$988,414
R44 · FY2023 · TR
A 2D Intestinal Crypt Platform for Compound Screens$900,267
R44 · FY2023 · DK · contact PI
MetabolGut: a rapid assay platform to evaluate the impact drugs on lipid-handlingpathways and chylomicron-associated drug distribution using stem cell-drivenhuman absorptive enterocytes.$343,297
R43 · FY2023 · TR · contact PI
InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammation$992,302
R44 · FY2022 · TR
A 2D Intestinal Crypt Platform for Compound Screens$988,431
R44 · FY2022 · DK
A Mucus-producing Intestinal Epithelium Model for In Vitro Drug Absorption Testing$293,991
R43 · FY2022 · DK
Planar culture of gastrointestinal stem cells for screening pharmaceuticals for adverse event risk$256,574
R43 · FY2022 · TR
Developing an optimized cell based platform for assays of the gastrointestinal enteroendocrine system$699,341
R44 · FY2021 · DK · contact PI
A 2D Intestinal Crypt Platform for Compound Screens$256,543
R43 · FY2021 · DK · contact PI
Co-culture cassette for anaerobes and primary human intestinal epithelium$745,742
R44 · FY2020 · DK · contact PI
Developing an optimized cell based platform for assays of the gastrointestinal enteroendocrine system$712,990
R44 · FY2020 · DK · contact PI
Generating drug-screenable primary human intestinal epithelium by gene-editing and transgenesis$245,920
R43 · FY2020 · DK · contact PI
Co-culture cassette for anaerobes and primary human intestinal epithelium$747,640
R44 · FY2019 · DK · contact PI
Developing a platform and optimized cell system for enteroendocrine cell-based assays and compound screening$223,049
R43 · FY2019 · DK · contact PI