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Mark E. Von Zastrow

University Of California, San Francisco

$25,439,062
Attributed
$33,961,363
Total exposure
25
Grants
16
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2.5M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$33,961,363 · 25

By mechanism

R01$14,426,661 · 4
P01$7,267,087 · 9
U01$6,373,388 · 2
R37$3,072,253 · 1
R61$1,299,270 · 1
K02$1,078,452 · 1

Top collaborators

Most similar at University Of California, San Francisco

Same institution · by research overlap

Others in their field

Top investigators on “Neurons

Research focus

NeuronsSignal TransductionMediatingOpioid ReceptorRegulationEndocytosisReceptorPharmaceutical PreparationsTraffickingCellsOpioidAddictionBaseG-Protein-Coupled ReceptorsPathway InteractionsAgonistIn VivoResponseCorpus Striatum StructureInsightMorphinePhosphorylationBiochemicalCell Membrane

Grant awards (126)

Mechanisms and Cellular Function of Opioid Receptor Endocytosis$376,226
R01 · FY2025 · DA · contact PI
Multiplex interrogation of neuromodulatory signaling in behaving animals with enhanced depth and resolution$883,967
U01 · FY2024 · NS
Mechanisms and Cellular Function of Opioid Receptor Endocytosis$376,575
R01 · FY2024 · DA · contact PI
Multiplex interrogation of neuromodulatory signaling in behaving animals with enhanced depth and resolution$570,101
U01 · FY2023 · NS
Membrane Trafficking of Opioid and Adrenergic Receptors$463,600
R01 · FY2023 · DA · contact PI
GPR88 localization to primary cilia and its impact on striatal cAMP signaling$393,050
R01 · FY2023 · MH · contact PI
Mechanisms and Cellular Function of Opioid Receptor Endocytosis$376,908
R01 · FY2023 · DA · contact PI
Multiplex interrogation of neuromodulatory signaling in behaving animals with enhanced depth and resolution$293,443
U01 · FY2023 · NS
Multiplex interrogation of neuromodulatory signaling in behaving animals with enhanced depth and resolution$863,993
U01 · FY2022 · NS
Membrane Trafficking of Opioid and Adrenergic Receptors$464,186
R01 · FY2022 · DA · contact PI
Precision pharmacology by local control of opioid receptors in neural circuits$427,965
R61 · FY2022 · DA · contact PI
GPR88 localization to primary cilia and its impact on striatal cAMP signaling$393,050
R01 · FY2022 · MH · contact PI
Mechanisms and Cellular Function of Opioid Receptor Endocytosis$377,238
R01 · FY2022 · DA · contact PI
Multiplex interrogation of neuromodulatory signaling in behaving animals with enhanced depth and resolution$869,559
U01 · FY2021 · NS
Membrane Trafficking of Opioid and Adrenergic Receptors$464,732
R01 · FY2021 · DA · contact PI
Precision pharmacology by local control of opioid receptors in neural circuits$427,965
R61 · FY2021 · DA · contact PI
GPR88 localization to primary cilia and its impact on striatal cAMP signaling$393,050
R01 · FY2021 · MH · contact PI
Membrane Trafficking of Opioid and Adrenergic Receptors$463,212
R01 · FY2020 · DA · contact PI
Precision pharmacology by local control of opioid receptors in neural circuits$443,340
R61 · FY2020 · DA · contact PI
GPR88 localization to primary cilia and its impact on striatal cAMP signaling$393,050
R01 · FY2020 · MH · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$355,393
R01 · FY2020 · DA · contact PI
Genetically encoded indicators for large-scale sensing of neuromodulatory signaling in behaving animals$960,752
U01 · FY2019 · NS
Membrane Trafficking of Opioid and Adrenergic Receptors$461,523
R01 · FY2019 · DA · contact PI
GPR88 localization to primary cilia and its impact on striatal cAMP signaling$390,312
R01 · FY2019 · MH · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$354,593
R01 · FY2019 · DA · contact PI
LASER REPLACEMENT DUE TO UNEXPECTED LOSS$37,936
R01 · FY2019 · DA · contact PI
Genetically encoded indicators for large-scale sensing of neuromodulatory signaling in behaving animals$953,117
U01 · FY2018 · NS
Membrane Trafficking of Opioid and Adrenergic Receptors$424,829
R01 · FY2018 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$353,794
R01 · FY2018 · DA · contact PI
Membrane Trafficking of Opioid and Adrenergic Receptors$155,438
R01 · FY2018 · DA · contact PI
Genetically encoded indicators for large-scale sensing of neuromodulatory signaling in behaving animals$978,456
U01 · FY2017 · NS
Membrane Trafficking of Opioid and Adrenergic Receptors$424,829
R01 · FY2017 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$352,994
R01 · FY2017 · DA · contact PI
Membrane Trafficking of Opioid and Adrenergic Receptors$420,581
R01 · FY2016 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$332,628
R01 · FY2016 · DA · contact PI
PROJECT 4 - Monoamine regulation of basal ganglia output$287,863
P01 · FY2016 · DA
PROJECT 1 - Synaptic selection by Monoamines$270,384
P01 · FY2016 · DA
PROJECT 3 - The Exocytotic Release of Dopamine$213,181
P01 · FY2016 · DA
PROJECT 2 - D1 receptor endocytosis and signaling$209,171
P01 · FY2016 · DA · contact PI
CORE: Communication$72,027
P01 · FY2016 · DA
Membrane Trafficking of Opioid and Adrenergic Receptors$417,796
R01 · FY2015 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$295,072
R01 · FY2015 · DA · contact PI
PROJECT 4 - Monoamine regulation of basal ganglia output$293,253
P01 · FY2015 · DA
PROJECT 1 - Synaptic selection by Monoamines$269,239
P01 · FY2015 · DA
PROJECT 3 - The Exocytotic Release of Dopamine$212,038
P01 · FY2015 · DA
PROJECT 2 - D1 receptor endocytosis and signaling$208,027
P01 · FY2015 · DA · contact PI
CORE: Communication$70,885
P01 · FY2015 · DA
Membrane Trafficking of Opioid and Adrenergic Receptors$423,489
R01 · FY2014 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$299,567
R01 · FY2014 · DA · contact PI
PROJECT 3 - The Exocytotic Release of Dopamine$271,380
P01 · FY2014 · DA
PROJECT 2 - D1 receptor endocytosis and signaling$265,051
P01 · FY2014 · DA · contact PI
PROJECT 4 - Monoamine regulation of basal ganglia output$259,501
P01 · FY2014 · DA
PROJECT 1 - Synaptic selection by Monoamines$229,142
P01 · FY2014 · DA
CORE: Communication$48,592
P01 · FY2014 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$309,119
R37 · FY2013 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$287,584
R01 · FY2013 · DA · contact PI
PROJECT 3 - The Exocytotic Release of Dopamine$242,824
P01 · FY2013 · DA
PROJECT 4 - Monoamine regulation of basal ganglia output$239,092
P01 · FY2013 · DA
PROJECT 2 - D1 receptor endocytosis and signaling$237,161
P01 · FY2013 · DA · contact PI
PROJECT 1 - Synaptic selection by Monoamines$206,229
P01 · FY2013 · DA
CORE: Communication$43,479
P01 · FY2013 · DA
Mechanisms Regulating Endocytosis of Opioid Receptors$34,278
R01 · FY2013 · DA · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$322,221
R37 · FY2012 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$299,567
R01 · FY2012 · DA · contact PI
PROJECT 3 - The Exocytotic Release of Dopamine$290,319
P01 · FY2012 · DA
PROJECT 4 - Monoamine regulation of basal ganglia output$285,263
P01 · FY2012 · DA
PROJECT 2 - D1 receptor endocytosis and signaling$259,452
P01 · FY2012 · DA · contact PI
PROJECT 1 - Synaptic selection by Monoamines$236,952
P01 · FY2012 · DA
CORE: Communication$47,568
P01 · FY2012 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$322,413
R37 · FY2011 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$299,567
R01 · FY2011 · DA · contact PI
GPCR REGULATION IN NOCICEPTORS$227,790
P01 · FY2011 · NS · contact PI
PHOSPHORYLATIVE DECODING OF OPIATE INTERACTIONS USING MASS SPECTROMETRY$33
P41 · FY2011 · RR · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$322,703
R37 · FY2010 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$278,363
R01 · FY2010 · DA · contact PI
GPCR REGULATION IN NOCICEPTORS$230,090
P01 · FY2010 · NS · contact PI
Endocytosis Mesolimbic Opioid and Dopamine Receptors$90,224
P01 · FY2010 · DA · contact PI
ENDOCYTOSIS OF MESOLIMBIC OPIOID AND DOPAMINE RECEPTORS$87,565
P01 · FY2010 · DA · contact PI
PHOSPHORYLATIVE DECODING OF OPIATE INTERACTIONS USING MASS SPECTROMETRY$1,766
P41 · FY2010 · RR · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$325,066
R37 · FY2009 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$281,175
R01 · FY2009 · DA · contact PI
GPCR REGULATION IN NOCICEPTORS$228,810
P01 · FY2009 · NS · contact PI
Post-endocytic Sorting of Opioid Receptors$118,584
K02 · FY2009 · DA · contact PI
Endocytosis Mesolimbic Opioid and Dopamine Receptors$85,890
P01 · FY2009 · DA · contact PI
ENDOCYTOSIS OF MESOLIMBIC OPIOID AND DOPAMINE RECEPTORS$85,860
P01 · FY2009 · DA · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$281,552
R37 · FY2008 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$281,175
R01 · FY2008 · DA · contact PI
GPCR REGULATION IN NOCICEPTORS$222,660
P01 · FY2008 · NS · contact PI
Post-endocytic Sorting of Opioid Receptors$118,584
K02 · FY2008 · DA · contact PI
ENDOCYTOSIS OF MESOLIMBIC OPIOID AND DOPAMINE RECEPTORS$90,855
P01 · FY2008 · DA · contact PI
Endocytosis Mesolimbic Opioid and Dopamine Receptors$88,219
P01 · FY2008 · DA · contact PI
PHOSPHORYLATIVE DECODING OF OPIATE INTERACTIONS USING MASS SPECTROMETRY$9,993
P41 · FY2008 · RR · contact PI
Extracellular Matrix Protein enhancement of Phagocytosis$359,123
R01 · FY2007 · GM · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$287,299
R37 · FY2007 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$285,984
R01 · FY2007 · DA · contact PI
GPCR REGULATION IN NOCICEPTORS$249,405
P01 · FY2007 · NS · contact PI
Post-endocytic Sorting of Opioid Receptors$118,584
K02 · FY2007 · DA · contact PI
ENDOCYTOSIS OF MESOLIMBIC OPIOID AND DOPAMINE RECEPTORS$82,095
P01 · FY2007 · DA · contact PI
Endocytosis Mesolimbic Opioid and Dopamine Receptors$79,716
P01 · FY2007 · DA · contact PI
2007 Molecular Pharmacology Gordon Research Conference$15,000
R13 · FY2007 · DA · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$295,880
R37 · FY2006 · DA · contact PI
Mechanisms Regulating Endocytosis of Opioid Receptors$293,569
R01 · FY2006 · DA · contact PI
ENDOCYTOSIS OF MESOLIMBIC OPIOID AND DOPAMINE RECEPTORS$149,835
P01 · FY2006 · DA · contact PI
Post-endocytic Sorting of Opioid Receptors$118,584
K02 · FY2006 · DA · contact PI
PHOSPHORYLATIVE DECODING OF OPIATE INTERACTIONS USING MASS SPECTROMETRY$48
P41 · FY2006 · RR · contact PI
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$303,000
R37 · FY2005 · DA
Post-endocytic Sorting of Opioid Receptors$118,584
K02 · FY2005 · DA
PHOSPHORYLATIVE DECODING OF OPIATE INTERACTIONS USING MASS SPECTROMETRY$4,636
P41 · FY2005 · RR
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$303,000
R37 · FY2004 · DA
PROTEINS REGULATING ENDOCYTOSIS OF OPIOID RECEPTORS$258,125
R01 · FY2004 · DA
PHOSPHORYLATIVE DECODING OF OPIATE INTERACTIONS USING MS$182
P41 · FY2004 · RR
PROTEINS REGULATING ENDOCYTOSIS OF OPIOID RECEPTORS$258,125
R01 · FY2003 · DA
NOVEL PROTEINS THAT REGULATE OPIOID RECEPTORS$121,383
K02 · FY2003 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$107,768
R29 · FY2003 · DA
PROTEINS REGULATING ENDOCYTOSIS OF OPIOID RECEPTORS$258,125
R01 · FY2002 · DA
NOVEL PROTEINS THAT REGULATE OPIOID RECEPTORS$121,383
K02 · FY2002 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$104,628
R29 · FY2002 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS IN NEURONS$0
P01 · FY2002 · DA
PROTEINS REGULATING ENDOCYTOSIS OF OPIOID RECEPTORS$258,125
R01 · FY2001 · DA
NOVEL PROTEINS THAT REGULATE OPIOID RECEPTORS$121,383
K02 · FY2001 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$101,579
R29 · FY2001 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS IN NEURONS$0
P01 · FY2001 · DA
PROTEINS REGULATING ENDOCYTOSIS OF OPIOID RECEPTORS$258,125
R01 · FY2000 · DA
NOVEL PROTEINS THAT REGULATE OPIOID RECEPTORS$121,383
K02 · FY2000 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS$98,619
R29 · FY2000 · DA
MEMBRANE TRAFFICKING OF OPIOID RECEPTORS IN NEURONS$0
P01 · FY2000 · DA