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Elena B Pasquale

Sanford Burnham Prebys Medical Discovery Institute

$23,453,916
Attributed
$29,535,128
Total exposure
25
Grants
19
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$48,228,683 · 27

By mechanism

P01$26,412,461 · 10
R01$19,662,994 · 9
R21$1,228,151 · 3
P30$757,161 · 3
R03$143,250 · 1
P41$24,666 · 1

Top collaborators

Most similar at Sanford Burnham Prebys Medical Discovery Institute

Same institution · by research overlap

Others in their field

Top investigators on “Signal Transduction

Research focus

Signal TransductionLigandsMalignant NeoplasmsAffectEph Family ReceptorsCellsPeptidesSignal PathwayPlayPhosphotransferasesProtein Tyrosine KinasePhosphorylationProteinsReceptorTumorComplexInsightReceptor Protein-Tyrosine KinasesStructureEphrinsBiochemicalLeadIn VivoCancer Cell

Grant awards (101)

EphA1 homotypic and EphA1-EphA2 heterotypic interactions in cell regulation$693,134
R01 · FY2025 · CA
EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction$535,039
R01 · FY2025 · CA · contact PI
Eph Receptor Heterointeractions in Signaling$480,649
R01 · FY2025 · GM · contact PI
Proteomics$255,113
P30 · FY2025 · CA · contact PI
EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction$88,084
R01 · FY2025 · CA · contact PI
Eph Receptor Heterointeractions in Signaling$27,399
R01 · FY2025 · GM · contact PI
EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction$508,287
R01 · FY2024 · CA · contact PI
Eph Receptor Heterointeractions in Signaling$484,417
R01 · FY2024 · GM · contact PI
Proteomics$248,523
P30 · FY2024 · CA · contact PI
EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction$111,834
R01 · FY2024 · CA · contact PI
Discovery of Selective Inhibitors for the EphA4 Kinase$760,964
R01 · FY2023 · AG
EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction$520,482
R01 · FY2023 · CA · contact PI
Eph Receptor Heterointeractions in Signaling$511,800
R01 · FY2023 · GM · contact PI
Discovery of Selective Inhibitors for the EphA4 Kinase$757,556
R01 · FY2022 · AG
EPHA2 Receptor Signaling in Breast Cancer Mechanotransduction$551,618
R01 · FY2022 · CA · contact PI
Ligand functional selectivity in EphA2 receptor signaling$459,877
R01 · FY2022 · GM · contact PI
Discovery of Selective Inhibitors for the EphA4 Kinase$754,237
R01 · FY2021 · AG
Ligand functional selectivity in EphA2 receptor signaling$459,877
R01 · FY2021 · GM · contact PI
Proteomics$253,525
P30 · FY2021 · CA · contact PI
Discovery of Selective Inhibitors for the EphA4 Kinase$751,756
R01 · FY2020 · AG
Ligand functional selectivity in EphA2 receptor signaling$459,877
R01 · FY2020 · GM · contact PI
Ligand functional selectivity in EphA2 receptor signaling$483,627
R01 · FY2019 · GM · contact PI
Cyclic EphA4 peptide antagonists for neuroprotection in ALS$690,441
R01 · FY2018 · NS · contact PI
Cyclic EphA4 peptide antagonists for neuroprotection in ALS$689,360
R01 · FY2017 · NS · contact PI
Cyclic EphA4 peptide antagonists for neuroprotection in ALS$688,311
R01 · FY2016 · NS · contact PI
Cyclic EphA4 peptide antagonists for neuroprotection in ALS$682,467
R01 · FY2015 · NS · contact PI
Structure and function of BCAR1 and BCAR3 association in breast cancer malignancy$429,624
R01 · FY2015 · CA · contact PI
Functional landscape of Eph receptor mutations in melanoma$212,063
R21 · FY2015 · CA · contact PI
Structure and function of BCAR1 and BCAR3 association in breast cancer malignancy$117,796
R01 · FY2015 · CA · contact PI
Structure and Function of BCAR1 and BCAR3 Association in Breast Cancer Malignancy$20,608
R01 · FY2015 · CA · contact PI
Targeting Eph receptors in cancer$1,430,343
P01 · FY2014 · CA · contact PI
Cyclic EphA4 peptide antagonists for neuroprotection in ALS$707,562
R01 · FY2014 · NS · contact PI
Structure and function of BCAR1 and BCAR3 association in breast cancer malignancy$416,735
R01 · FY2014 · CA · contact PI
Administrative$357,583
P01 · FY2014 · CA · contact PI
Functional landscape of Eph receptor mutations in melanoma$254,475
R21 · FY2014 · CA · contact PI
Targeting Eph receptors in cancer$1,387,937
P01 · FY2013 · CA · contact PI
Structure and function of BCAR1 and BCAR3 association in breast cancer malignancy$403,847
R01 · FY2013 · CA · contact PI
Administrative$346,983
P01 · FY2013 · CA · contact PI
Targeting Eph receptors in cancer$1,458,943
P01 · FY2012 · CA · contact PI
Structure and function of BCAR1 and BCAR3 association in breast cancer malignancy$429,624
R01 · FY2012 · CA · contact PI
Administrative$400,885
P01 · FY2012 · CA · contact PI
Targeting Eph receptors in cancer$1,459,937
P01 · FY2011 · CA · contact PI
Eph Receptor Targeting Strategies$441,467
P01 · FY2011 · CA · contact PI
Structure and function of BCAR1 and BCAR3 association in breast cancer malignancy$420,813
R01 · FY2011 · CA · contact PI
Ephrin-A3 in Neuron-Glia Communication$347,943
P01 · FY2011 · HD · contact PI
Cell-based screening for EphA2 receptor inhibitors$47,750
R21 · FY2011 · NS · contact PI
Administrative$25,248
P01 · FY2011 · CA · contact PI
REGULATION OF ASTROCYTE PROCESSES BY EPHRIN-A3$24,666
P41 · FY2011 · RR · contact PI
Targeting Eph receptors in cancer$1,529,049
P01 · FY2010 · CA · contact PI
Eph Receptor Targeting Strategies$675,725
P01 · FY2010 · CA · contact PI
Ephrin-A3 in Neuron-Glia Communication$398,453
P01 · FY2010 · HD · contact PI
The EphB4 Receptor as a Novel Breast Cancer Target$394,425
R01 · FY2010 · CA · contact PI
Optimization of EphA4 antagonists for CNS disorders$236,363
R21 · FY2010 · NS · contact PI
Administrative$21,140
P01 · FY2010 · CA · contact PI
Ephrin-A3 in Neuron-Glia Communication$390,747
P01 · FY2009 · HD · contact PI
The EphB4 Receptor as a Novel Breast Cancer Target$387,328
R01 · FY2009 · CA · contact PI
Optimization of EphA4 antagonists for CNS disorders$286,500
R21 · FY2009 · NS · contact PI
Cell-based screening for EphA2 receptor inhibitors$191,000
R21 · FY2009 · NS · contact PI
Signaling Interactions in Cell Survival and Invasion$2,290,876
P01 · FY2008 · CA · contact PI
SHEP1 a Partner for p130Cas in Intergrin Signaling$422,342
P01 · FY2008 · CA · contact PI
Crk/DOCK Complex in Rac Signaling$422,341
P01 · FY2008 · CA · contact PI
The EphB4 Receptor as a Novel Breast Cancer Target$388,020
R01 · FY2008 · CA · contact PI
Ephrin-A3 in Neuron-Glia Communication$379,370
P01 · FY2008 · HD · contact PI
Signaling Interactions in Cell Survival and Invasion$70,414
P01 · FY2008 · CA · contact PI
Signaling Interactions in Cell Survival and Invasion$2,268,192
P01 · FY2007 · CA · contact PI
SHEP1 a Partner for p130Cas in Intergrin Signaling$418,280
P01 · FY2007 · CA · contact PI
Crk/DOCK Complex in Rac Signaling$418,277
P01 · FY2007 · CA · contact PI
The EphB4 Receptor as a Novel Breast Cancer Target$385,957
R01 · FY2007 · CA · contact PI
Heparan Sulfate in Schwann Cell Development and Myelination$383,412
P01 · FY2007 · HD · contact PI
Signaling Interactions in Cell Survival and Invasion$70,414
P01 · FY2007 · CA · contact PI
Signaling Interactions in Cell Survival and Invasion$2,267,892
P01 · FY2006 · CA · contact PI
Dendritic Repulsion by the EphA4 Receptor$400,756
R01 · FY2006 · NS · contact PI
The EphB4 Receptor as a Novel Breast Cancer Target$377,580
R01 · FY2006 · CA · contact PI
SHEP1 a Partner for p130Cas in Intergrin Signaling$217,485
P01 · FY2006 · CA · contact PI
Crk/DOCK Complex in Rac Signaling$217,484
P01 · FY2006 · CA · contact PI
EphA4 Receptor Antagonists for CNS Regeneration(RMI)$47,750
R03 · FY2006 · NS · contact PI
Signaling Interactions in Cell Survival and Invasion$2,261,386
P01 · FY2005 · CA
Dendritic Repulsion by the EphA4 Receptor$410,400
R01 · FY2005 · NS
SHEP1 a Partner for p130Cas in Intergrin Signaling$211,151
P01 · FY2005 · CA
Crk/DOCK Complex in Rac Signaling$211,150
P01 · FY2005 · CA
EphA4 Receptor Antagonists for CNS Regeneration(RMI)$95,500
R03 · FY2005 · NS
Signaling Interactions in Cell Survival and Invasion$2,198,172
P01 · FY2004 · CA
Dendritic Repulsion by the EphA4 Receptor$433,000
R01 · FY2004 · NS
SHEP1 a Partner for p130Cas in Intergrin Signaling$205,000
P01 · FY2004 · CA
Crk/DOCK Complex in Rac Signaling$205,000
P01 · FY2004 · CA
Dendritic Repulsion by the EphA4 Receptor$433,000
R01 · FY2003 · NS
EPH RECEPTORS AND EPHRINS IN VISUAL SYSTEM ORGANIZATION$324,193
R01 · FY2002 · EY
EphB2/Ephrin-B1 signals that govern tissue patterning$200,480
P01 · FY2002 · HD
EPH RECEPTORS AND EPHRINS IN TUMOR ANGIOGENESIS$0
P01 · FY2002 · CA
Core--Histopathology and EM$0
P30 · FY2002 · CA
EPH RECEPTORS AND EPHRINS IN TUMOR ANGIOGENESIS$0
P01 · FY2002 · CA
EPH RECEPTORS AND EPHRINS IN TUMOR ANGIOGENESIS$0
P01 · FY2002 · CA
EPH RECEPTORS AND EPHRINS IN TUMOR ANGIOGENESIS$0
P01 · FY2002 · CA
EPH RECEPTORS AND EPHRINS IN VISUAL SYSTEM ORGANIZATION$317,450
R01 · FY2001 · EY
EphB2/Ephrin-B1 signals that govern tissue patterning$200,480
P01 · FY2001 · HD
EPH RECEPTORS AND EPHRINS IN TUMOR ANGIOGENESIS$0
P01 · FY2001 · CA
Core--Histopathology and EM$0
P30 · FY2001 · CA
EPH RECEPTORS AND EPHRINS IN VISUAL SYSTEM ORGANIZATION$313,183
R01 · FY2000 · EY
EphB2/Ephrin-B1 signals that govern tissue patterning$200,480
P01 · FY2000 · HD
Core--Histopathology and EM$0
P30 · FY2000 · CA
EPH RECEPTORS AND EPHRINS IN TUMOR ANGIOGENESIS$0
P01 · FY2000 · CA