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Matthew Donald Shoulders

Massachusetts Institute Of Technology

$10,682,867
Attributed
$10,682,867
Total exposure
8
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $2.4M · FY201525
$2.5M$1.9M$1.3M$625K$0
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$10,682,867 · 8

By mechanism

R01$5,333,409 · 3
DP2$2,340,000 · 1
R35$2,130,157 · 1
R21$419,678 · 1
R03$234,000 · 1
R56$225,623 · 1

Top collaborators

No co-investigators on record.

Most similar at Massachusetts Institute Of Technology

Same institution · by research overlap

Others in their field

Top investigators on “Cells

Research focus

CellsProteinsMolecular ChaperonesMutationProteostasisInsightVariantBiologyProtein FoldingComplexMolecularDefectPathologicEnvironmentProductionEvolutionBaseQuality ControlTargeted TreatmentBiophysicsBiologicalBiological ModelsOrganismEnsure

Grant awards (27)

Collagen Proteostasis in Health and Disease$599,017
R01 · FY2025 · AR · contact PI
Defining the Interplay Between Viral Adaptation and Host Proteostasis$584,656
R01 · FY2025 · AI · contact PI
Collagen Proteostasis in Health and Disease$680,325
R01 · FY2024 · AR · contact PI
Defining the Interplay Between Viral Adaptation and Host Proteostasis$584,656
R01 · FY2024 · AI · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$373,099
R35 · FY2024 · GM · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$22,427
R35 · FY2024 · GM · contact PI
Defining the Interplay Between Viral Adaptation and Host Proteostasis$584,656
R01 · FY2023 · AI · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$373,099
R35 · FY2023 · GM · contact PI
Collagen Proteostasis in Heath and Disease$225,623
R56 · FY2023 · AR · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$89,710
R35 · FY2023 · GM · contact PI
Defining the Interplay Between Viral Adaptation and Host Proteostasis$608,610
R01 · FY2022 · AI · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$373,099
R35 · FY2022 · GM · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$67,282
R35 · FY2022 · GM · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$373,099
R35 · FY2021 · GM · contact PI
Defining and Modulating Mechanisms of Collagen Proteostasis$330,129
R01 · FY2021 · AR · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$85,243
R35 · FY2021 · GM · contact PI
Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution$373,099
R35 · FY2020 · GM · contact PI
Defining and Modulating Mechanisms of Collagen Proteostasis$340,340
R01 · FY2020 · AR · contact PI
Defining and Modulating Mechanisms of Collagen Proteostasis$340,340
R01 · FY2019 · AR · contact PI
Defining and Modulating Mechanisms of Collagen Proteostasis$340,340
R01 · FY2018 · AR · contact PI
Defining and Modulating Mechanisms of Collagen Proteostasis$340,340
R01 · FY2017 · AR · contact PI
Aggregate Proximity-Induced, Proteostasis Network-Modulated Destabilization of the Proteome$190,225
R21 · FY2017 · AG · contact PI
Unveiling the Proteostasis Network of Normal and Disease_Causing Collagen_I$78,000
R03 · FY2017 · AR · contact PI
Aggregate Proximity-Induced, Proteostasis Network-Modulated Destabilization of the Proteome$229,453
R21 · FY2016 · AG · contact PI
Unveiling the Proteostasis Network of Normal and Disease_Causing Collagen_I$78,000
R03 · FY2016 · AR · contact PI
Continuous Directed Evolution of Biomolecules in Human Cells for Medical Research$2,340,000
DP2 · FY2015 · GM · contact PI
Unveiling the Proteostasis Network of Normal and Disease_Causing Collagen_I$78,000
R03 · FY2015 · AR · contact PI