← Leaderboards
Douglas R Seals
University Of Colorado
$39,040,406
Attributed
$42,283,939
Total exposure
31
Grants
24
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $3.6M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$42,283,939 · 31
By mechanism
R01$35,057,384 · 12
R21$3,687,082 · 8
R37$2,985,933 · 1
M01$277,776 · 9
R41$275,764 · 1
Top collaborators
- Simon Melov10 shared
- Judith Campisi8 shared
Others in their field
Top investigators on “Aging”
- Lawrence Corey · Fred Hutchinson Cancer Center$506,603,345
- David R. Weir · University Of Michigan At Ann Arbor$421,002,438
- Margaret Juliana McElrath · Fred Hutchinson Cancer Center$351,438,389
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$281,021,854
- George R Seage · Abt Associates, Inc.$218,167,298
- Eric Jeffrey Topol · Cleveland Clinic Lerner Col/Med-Cwru$210,610,900
Research focus
AgingMediatingElderlyOxidative StressInsightMiddle AgeAdultEndotheliumArteriesRandomizedBlood VesselsBiological AvailabilityAcutePlasmaNitric OxideWomanCardiovascular DiseasesCardiovascular Disorder RiskEndothelial CellsLinkMolecularAntioxidantsResponseAge Related
Grant awards (131)
Passive heat therapy for lowering systolic blood pressure and improving vascular function in mid-life and older adults$616,463
R01 · FY2025 · AG · contact PI
Inspiratory muscle strength training for lowering blood pressure and improving endothelial function in postmenopausal women: comparison with "standard of care" aerobic exercise$568,974
R01 · FY2025 · AG · contact PI
Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans$568,439
R01 · FY2025 · AG · contact PI
Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans$580,039
R01 · FY2024 · AG · contact PI
Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans$354,164
R01 · FY2024 · AG · contact PI
Passive heat therapy for lowering systolic blood pressure and improving vascular function in mid-life and older adults$629,045
R01 · FY2023 · AG · contact PI
Inspiratory muscle strength training for lowering blood pressure and improving endothelial function in postmenopausal women: comparison with "standard of care" aerobic exercise$589,167
R01 · FY2023 · AG · contact PI
Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans$580,039
R01 · FY2023 · AG · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$437,530
R01 · FY2023 · AG · contact PI
Passive heat therapy for lowering systolic blood pressure and improving vascular function in mid-life and older adults$375,588
R01 · FY2023 · AG · contact PI
Feasibility and design of a novel smartphone app to deliver blood pressure-lowering inspiratory muscle strength training$275,764
R41 · FY2023 · HL · contact PI
Targeting cellular senescence to prevent accelerated vascular aging induced by the common chemotherapeutic agent doxorubicin$234,750
R21 · FY2023 · AG · contact PI
Role of cellular senescence in cardiovascular aging$738,006
R01 · FY2022 · AG
Passive heat therapy for lowering systolic blood pressure and improving vascular function in mid-life and older adults$654,978
R01 · FY2022 · AG · contact PI
Inspiratory muscle strength training for lowering blood pressure and improving endothelial function in postmenopausal women: comparison with "standard of care" aerobic exercise$580,586
R01 · FY2022 · AG · contact PI
Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans$580,039
R01 · FY2022 · AG · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$431,134
R01 · FY2022 · AG · contact PI
Inspiratory muscle strength training for lowering blood pressure and improving endothelial function in postmenopausal women: comparison with "standard of care" aerobic exercise$372,075
R01 · FY2022 · AG · contact PI
Targeting cellular senescence to prevent accelerated vascular aging induced by the common chemotherapeutic agent doxorubicin$195,625
R21 · FY2022 · AG · contact PI
Role of cellular senescence in cardiovascular aging$36,681
R01 · FY2022 · AG
Role of cellular senescence in cardiovascular aging$855,648
R01 · FY2021 · AG
Inspiratory muscle strength training for lowering blood pressure and improving endothelial function in postmenopausal women: comparison with "standard of care" aerobic exercise$603,004
R01 · FY2021 · AG · contact PI
Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans$593,539
R01 · FY2021 · AG · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$484,632
R01 · FY2021 · AG · contact PI
Role of cellular senescence in cardiovascular aging$177,483
R01 · FY2021 · AG
Role of cellular senescence in cardiovascular aging$784,023
R01 · FY2020 · AG
Translational Studies of Age-Associated Arterial Dysfunction, Western Diet and Aerobic Exercise: Role of the Gut Microbiome$719,929
R01 · FY2020 · HL · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$571,966
R01 · FY2020 · AG · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$502,464
R01 · FY2020 · AG · contact PI
DMB (3,3-dimethyl-1-butanol) as a novel translational strategy for preventing and treating gut dysbiosis-associated arterial aging$197,803
R21 · FY2020 · AG · contact PI
Inspiratory muscle strength training for lowering blood pressure in hypertensive mid-life adults$193,278
R21 · FY2020 · AG · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$153,484
R01 · FY2020 · AG · contact PI
Role of cellular senescence in cardiovascular aging$60,181
R01 · FY2020 · AG
Role of cellular senescence in cardiovascular aging$788,547
R01 · FY2019 · AG
Translational Studies of Age-Associated Arterial Dysfunction, Western Diet and Aerobic Exercise: Role of the Gut Microbiome$722,331
R01 · FY2019 · HL · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$489,677
R01 · FY2019 · AG · contact PI
Role of cellular senescence in cardiovascular aging$480,373
R01 · FY2019 · AG
Inspiratory muscle strength training for lowering blood pressure in hypertensive mid-life adults$257,637
R21 · FY2019 · AG · contact PI
DMB (3,3-dimethyl-1-butanol) as a novel translational strategy for preventing and treating gut dysbiosis-associated arterial aging$238,806
R21 · FY2019 · AG · contact PI
Role of cellular senescence in cardiovascular aging$177,398
R01 · FY2019 · AG
Inspiratory muscle strength training for lowering blood pressure in hypertensive mid-life adults$155,277
R21 · FY2019 · AG · contact PI
Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults$17,832
R01 · FY2019 · AG · contact PI
Role of cellular senescence in cardiovascular aging$826,376
R01 · FY2018 · AG
Translational Studies of Age-Associated Arterial Dysfunction, Western Diet and Aerobic Exercise: Role of the Gut Microbiome$734,456
R01 · FY2018 · HL · contact PI
Nitrite Supplementation for Improving Physiological Function in Older Adults$458,215
R01 · FY2018 · AG · contact PI
Translational Studies of Age-Associated Arterial Dysfunction, Western Diet and Aerobic Exercise: Role of the Gut Microbiome$152,698
R01 · FY2018 · HL · contact PI
Translational Studies of Age-Associated Arterial Dysfunction, Western Diet and Aerobic Exercise: Role of the Gut Microbiome$765,515
R01 · FY2017 · HL · contact PI
Nitrite Supplementation for Improving Physiological Function in Older Adults$465,335
R01 · FY2017 · AG · contact PI
MitoQ Supplementation for Improving Vascular Endothelial Function in Older Adults$231,380
R21 · FY2017 · AG · contact PI
Translational Studies of Interleukin-37, a Novel Anti-inflammatory Cytokine, for Prevention and Treatment of Inflamm-aging and Age-Associated Physiological Dysfunction$194,688
R21 · FY2017 · AG · contact PI
Nitrite Supplementation for Improving Physiological Function in Older Adults$473,129
R01 · FY2016 · AG · contact PI
Translational Studies of Interleukin-37, a Novel Anti-inflammatory Cytokine, for Prevention and Treatment of Inflamm-aging and Age-Associated Physiological Dysfunction$233,188
R21 · FY2016 · AG · contact PI
MitoQ Supplementation for Improving Vascular Endothelial Function in Older Adults$199,246
R21 · FY2016 · AG · contact PI
Nitrite Supplementation for Improving Physiological Function in Older Adults$481,980
R01 · FY2015 · AG · contact PI
Nitrite Supplementation for Improving Physiological Function in Older Adults$507,401
R01 · FY2014 · AG · contact PI
Aging and Arterial Dysfunction with a Western Diet: Exercise and AMPK$428,213
R01 · FY2014 · HL · contact PI
Clinical Translation of Curcumin Therapy to Treat Arterial Aging$250,770
R21 · FY2014 · AG · contact PI
Nitrite Supplementation for Improving Physiological Function in Older Adults$57,916
R01 · FY2014 · AG · contact PI
Aging and Arterial Dysfunction with a Western Diet: Exercise and AMPK$362,950
R01 · FY2013 · HL · contact PI
Human Aging, Exercise & FMD: Translational Physiology$318,719
R37 · FY2013 · AG · contact PI
Clinical Translation of Curcumin Therapy to Treat Arterial Aging$233,718
R21 · FY2013 · AG · contact PI
Aging and Arterial Dysfunction with a Western Diet: Exercise and AMPK$18,569
R01 · FY2013 · HL · contact PI
Clinical Translation of Curcumin Therapy to Treat Arterial Aging$11,645
R21 · FY2013 · AG · contact PI
Aging and Arterial Dysfunction with a Western Diet: Exercise and AMPK$381,250
R01 · FY2012 · HL · contact PI
Human Aging, Exercise & FMD: Translational Physiology$286,917
R37 · FY2012 · AG · contact PI
Clinical Translation of Nitrite Therapy to Treat Arterial Aging in Humans$192,349
R21 · FY2012 · HL · contact PI
Human Aging, Exercise & FMD: Translational Physiology$58,705
R37 · FY2012 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$5,000
R37 · FY2012 · AG · contact PI
Aging and Arterial Dysfunction with a Western Diet: Exercise and AMPK$380,000
R01 · FY2011 · HL · contact PI
Human Aging, Exercise & FMD: Translational Physiology$295,529
R37 · FY2011 · AG · contact PI
Clinical Translation of Nitrite Therapy to Treat Arterial Aging in Humans$225,172
R21 · FY2011 · HL · contact PI
Reduced Inflammatory Suppression of EDD with Habitual Exercise in Older Adults$494,130
R01 · FY2010 · AG · contact PI
Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults$476,094
R01 · FY2010 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$307,470
R37 · FY2010 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$5,000
R37 · FY2010 · AG · contact PI
Reduced Inflammatory Suppression of EDD with Habitual Exercise in Older Adults$485,124
R01 · FY2009 · AG · contact PI
Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults$459,556
R01 · FY2009 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$310,575
R37 · FY2009 · AG · contact PI
Human Aging and B-adrenergic Modulation of Thermogenesis$266,341
R01 · FY2009 · AG · contact PI
Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults$22,422
R01 · FY2009 · AG · contact PI
Reduced Inflammatory Suppression of EDD with Habitual Exercise in Older Adults$22,422
R01 · FY2009 · AG · contact PI
Reduced Inflammatory Suppression of EDD with Habitual Exercise in Older Adults$471,537
R01 · FY2008 · AG · contact PI
Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults$438,450
R01 · FY2008 · AG · contact PI
Human Aging and B-adrenergic Modulation of Thermogenesis$266,485
R01 · FY2008 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$262,270
R37 · FY2008 · AG · contact PI
ROLE OF PPARA IN THE PREVENTION OF VASCULAR AGING BY HABITUAL EXERCISE$989
M01 · FY2008 · RR · contact PI
Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults$439,614
R01 · FY2007 · AG · contact PI
Hormone Replacement Therapy, SERMs & Leg Blood Flow in Postmenopausal Women$353,197
R01 · FY2007 · AG · contact PI
Human Aging and B-adrenergic Modulation of Thermogenesis$272,067
R01 · FY2007 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$268,036
R37 · FY2007 · AG · contact PI
Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults$444,962
R01 · FY2006 · AG · contact PI
HRT, SERMs and LEG BLOOD FLOW IN POSTMENOPAUSAL WOMEN$363,746
R01 · FY2006 · AG · contact PI
Human Aging and B-adrenergic Modulation of Thermogenesis$284,167
R01 · FY2006 · AG · contact PI
Human Aging, Exercise & FMD: Translational Physiology$276,456
R37 · FY2006 · AG · contact PI
MOLECULAR MECHANISMS ASSOCIATED WITH CARDIOVASCULAR AGING$22,899
M01 · FY2006 · RR · contact PI
ROLE OF TETRAHYDROBIOPTERIN DEFICIENCY IN CARDIOVASCULAR FUNCTION WITH AGING$6,498
M01 · FY2006 · RR · contact PI
Human Aging, Exercise & FMD: Translational Physiology$5,000
R37 · FY2006 · AG · contact PI
ROLE OF XANTHINE OXIDASE IN THE AGE-RELATED DECLINE IN FLOW-MEDIATED DILATION$3,713
M01 · FY2006 · RR · contact PI
HRT, SERMs and LEG BLOOD FLOW IN POSTMENOPAUSAL WOMEN$372,188
R01 · FY2005 · AG
Age, Gender, Exercise &Autonomic-Physiological Function$367,500
R01 · FY2005 · AG
Human Aging and B-adrenergic Modulation of Thermogenesis$292,704
R01 · FY2005 · AG
Human Aging, Exercise &FMD: Translational Physiology$283,521
R37 · FY2005 · AG
MOLECULAR MECHANISMS ASSOCIATED WITH CARDIOVASCULAR AGING$85,782
M01 · FY2005 · RR
ROLE OF XANTHINE OXIDASE IN THE AGE-RELATED DECLINE IN FLOW-MEDIATED DILATION$28,880
M01 · FY2005 · RR
ROLE OF TETRAHYDROBIOPTERIN DEFICIENCY IN CARDIOVASCULAR FUNCTION WITH AGING$12,867
M01 · FY2005 · RR
EFFECTS OF OXIDATIVE STRESS ON AUTONOMIC-CARDIOVASCULAR FUNCTION WITH HUMAN AGIG$10,866
M01 · FY2005 · RR
Human Aging, Exercise &FMD: Translational Physiology$5,000
R37 · FY2005 · AG
Human Aging, Exercise &FMD: Translational Physiology$5,000
R37 · FY2005 · AG
HUMAN AGING, EXERCISE AND ENDOTHELIUM-DEPENDENT VASODILATION: TRANSLATIONAL PHY$1,430
M01 · FY2005 · RR
HRT, SERMs and LEG BLOOD FLOW IN POSTMENOPAUSAL WOMEN$370,938
R01 · FY2004 · AG
Age, Gender, Exercise &Autonomic-Physiological Function$367,500
R01 · FY2004 · AG
AGE, EXERCISE, THERMOGENESIS AND POSTPRANDIAL HYPOTENSIO$320,366
R01 · FY2004 · AG
Human Aging, Exercise &FMD: Translational Physiology$292,735
R37 · FY2004 · AG
Effects of Oxidative Stress on Autonomic-Cardiovascular Function with Human Agig$34,813
M01 · FY2004 · RR
Role of Tetrahydrobiopterin Deficiency in Cardiovascular Function with Aging$33,935
M01 · FY2004 · RR
Molecular Mechanism Associated with Cardiovascular Aging$33,057
M01 · FY2004 · RR
Role of Xanthine Oxidase in age-related dilation decline$2,047
M01 · FY2004 · RR
SODIUM RESTRICTION &ARTERIAL COMPLIANCE IN OLDER HUMANS$407,203
R01 · FY2003 · AG
Age, Gender, Exercise &Autonomic-Physiological Function$367,500
R01 · FY2003 · AG
AGE, EXERCISE, THERMOGENESIS AND POSTPRANDIAL HYPOTENSIO$281,723
R01 · FY2003 · AG
SODIUM RESTRICTION &ARTERIAL COMPLIANCE IN OLDER HUMANS$396,078
R01 · FY2002 · AG
Age, Gender, Exercise &Autonomic-Physiological Function$367,500
R01 · FY2002 · AG
AGE, EXERCISE, THERMOGENESIS AND POSTPRANDIAL HYPOTENSIO$273,932
R01 · FY2002 · AG
Mechanisms for Reduced Limb Perfusion with Human Aging$220,650
R21 · FY2002 · AG
SODIUM RESTRICTION &ARTERIAL COMPLIANCE IN OLDER HUMANS$386,327
R01 · FY2001 · AG
Age, Gender, Exercise &Autonomic Physiological Function$368,417
R01 · FY2001 · AG
AGE, EXERCISE, THERMOGENESIS AND POSTPRANDIAL HYPOTENSIO$265,260
R01 · FY2001 · AG
Mechanisms for Reduced Limb Perfusion with Human Aging$221,100
R21 · FY2001 · AG
SODIUM RESTRICTION &ARTERIAL COMPLIANCE IN OLDER HUMANS$375,815
R01 · FY2000 · AG
SYMPATHETIC NERVOUS SYSTEM ACTIVITY AND HUMAN AGING$290,276
R01 · FY2000 · AG
AGE, EXERCISE, THERMOGENESIS AND POSTPRANDIAL HYPOTENSIO$256,382
R01 · FY2000 · AG