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Yu Chen
University Of South Florida
$6,268,555
Attributed
$10,279,039
Total exposure
7
Grants
5
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $3.7M · FY2013–25$5M$3.8M$2.5M$1.3M$0
'13
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'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$10,279,039 · 7
By mechanism
R01$8,605,064 · 3
R21$1,673,975 · 4
Top collaborators
- Adam R Renslo7 shared
- Jianfeng Cai2 shared
- Prahathees Jai Eswara2 shared
- David E Kang2 shared
- Xingmin Sun1 shared
Most similar at University Of South Florida
Same institution · by research overlap
- Bill J Baker$1,852,003
- Lindsey Neil Shaw$7,544,341
- Yongrong Zhang$471,371
Others in their field
Top investigators on “Structure”
- David Heimbrook · Leidos Biomedical Research, Inc.$475,333,582
- Barton F Haynes · Duke University$444,977,767
- Lawrence Corey · Fred Hutchinson Cancer Center$334,646,086
- Gary D Acton · University Of California-Davis$320,373,312
- Mitchell J Malone · Texas A&M Research Foundation$320,373,312
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$315,257,203
Research focus
StructureLeadEnzymesDesignPharmaceutical ChemistryAntibioticsPenicillin-Binding ProteinsLigandsIn VitroX-Ray CrystallographyMonobactamsActive SitesResistanceBaseResistance MechanismHydrolysisSerineBeta-LactamaseResearch PersonnelAnti-Bacterial AgentsAffinityPropertyBacterial ResistanceProduction
Grant awards (20)
Clostridioides difficile Zinc-binding PBPs as anti-sporulation targets$2,872,722
R01 · FY2025 · AI · contact PI
Evolution and inhibition of carbapenemase in beta-lactam resistance$779,337
R01 · FY2025 · AI · contact PI
Evolution and inhibition of carbapenemase in beta-lactam resistance$748,760
R01 · FY2024 · AI · contact PI
Evolution and inhibition of carbapenemase in beta-lactam resistance$730,394
R01 · FY2023 · AI · contact PI
Evolution and inhibition of carbapenemase in beta-lactam resistance$738,466
R01 · FY2022 · AI · contact PI
Characterization and Inhibition of protein-protein interactions involving Staphylococcus aureus GpsB$186,875
R21 · FY2022 · AI · contact PI
Evolution and inhibition of carbapenemase in beta-lactam resistance$751,397
R01 · FY2021 · AI · contact PI
Characterization and Inhibition of protein-protein interactions involving Staphylococcus aureus GpsB$224,250
R21 · FY2021 · AI · contact PI
Novel inhibitor discovery against Pseudomonas aeruginosa PBP3$186,875
R21 · FY2020 · AI · contact PI
Novel inhibitor discovery against Pseudomonas aeruginosa PBP3$224,250
R21 · FY2019 · AI · contact PI
Biophysical Fragment Screening and Structure Determination for Class A, B, and D Carbapenemases$193,625
R21 · FY2019 · AI
Biophysical Fragment Screening and Structure Determination for Class A, B, and D Carbapenemases$246,975
R21 · FY2018 · AI
Evolution and inhibition of beta-lactamase activity in antibiotic resistance$373,368
R01 · FY2017 · AI · contact PI
Evolution and inhibition of beta-lactamase activity in antibiotic resistance$417,701
R01 · FY2016 · AI · contact PI
Structure-based Identification and Functional Characterization of SSH1 Inhibitors$186,875
R21 · FY2016 · AG
Evolution and inhibition of beta-lactamase activity in antibiotic resistance$415,458
R01 · FY2015 · AI · contact PI
Structure-based Identification and Functional Characterization of SSH1 Inhibitors$224,250
R21 · FY2015 · AG
Evolution and inhibition of beta-lactamase activity in antibiotic resistance$373,018
R01 · FY2014 · AI · contact PI
Evolution and inhibition of beta-lactamase activity in antibiotic resistance$42,090
R01 · FY2014 · AI · contact PI
Evolution and inhibition of beta-lactamase activity in antibiotic resistance$362,353
R01 · FY2013 · AI · contact PI