← Leaderboards
Zhong-Yin Zhang
Purdue University
$21,340,069
Attributed
$21,340,069
Total exposure
13
Grants
10
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).
Funding over time
peak $2.1M · FY2005–25$2.5M$1.9M$1.3M$625K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$21,583,467 · 14
By mechanism
R01$15,383,919 · 8
U54$5,316,417 · 3
P30$456,548 · 1
R56$406,500 · 1
P41$20,083 · 1
Top collaborators
- Bruce T Lamb1 shared
- Alan D. Palkowitz1 shared
Most similar at Purdue University
Same institution · by research overlap
- Michael Keith Wendt$4,884,793
Others in their field
Top investigators on “Protein Tyrosine Phosphatase”
- Nicholas K Tonks · Cold Spring Harbor Laboratory$25,899,340
- Nunzio Bottini · University Of Southern California$17,835,887
- Benjamin G. Neel · New York University School Of Medicine$15,765,169
- Gen-Sheng Feng · University Of California, San Diego$14,257,616
- Tony R. Hunter · Salk Institute For Biological Studies$12,894,505
- Arthur Weiss · University Of California, San Francisco$11,859,077
Research focus
Protein Tyrosine PhosphataseMolecularBaseProgramsMalignant NeoplasmsStructureHuman DiseaseLinkSignal TransductionEtiologyProtein Tyrosine KinaseTyrosine PhosphorylationProteinsLeadOncogenicSmall MoleculePhosphoric Monoester HydrolasesMediatingEventProteomicsActive SitesEquilibriumHigh Throughput ScreeningPathway Interactions
Grant awards (67)
Primary screening and hit follow up to identify the first selective inhibitors of PLC?1 and PLC?2$572,254
R01 · FY2025 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$353,306
R01 · FY2025 · CA · contact PI
Assay Development and High Throughput Screening Core$858,054
U54 · FY2023 · AG · contact PI
Structure/Function of Protein Tyrosine Phosphatases$325,618
R01 · FY2023 · CA · contact PI
Assay Development and High Throughput Screening Core$935,553
U54 · FY2022 · AG · contact PI
Structure/Function of Protein Tyrosine Phosphatases$319,105
R01 · FY2022 · CA · contact PI
Assay Development and High Throughput Screening Core$1,005,304
U54 · FY2021 · AG · contact PI
Development of SHP2 inhibitors for targeted anti-cancer therapy$429,035
R01 · FY2021 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$325,618
R01 · FY2021 · CA · contact PI
Assay Development and High Throughput Screening Core$1,144,804
U54 · FY2020 · AG · contact PI
Development of SHP2 inhibitors for targeted anti-cancer therapy$435,963
R01 · FY2020 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$325,618
R01 · FY2020 · CA · contact PI
Enzymatic substrates for HTS: IUSM Alzheimer's Disease Drug Discovery Center$243,398
U54 · FY2020 · AG
Assay Development and High Throughput Screening Core$1,129,304
U54 · FY2019 · AG · contact PI
Development of SHP2 inhibitors for targeted anti-cancer therapy$439,449
R01 · FY2019 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$325,618
R01 · FY2019 · CA · contact PI
Development of SHP2 inhibitors for targeted anti-cancer therapy$469,466
R01 · FY2018 · CA · contact PI
Development of SHP2 inhibitors for targeted anti-cancer therapy$481,271
R01 · FY2017 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$348,750
R01 · FY2017 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$244,726
R01 · FY2016 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$25,327
R01 · FY2016 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$301,815
R01 · FY2015 · CA · contact PI
Small Molecule Inhibitors for the Oncogenic Protein Tyrosine Phosphatase SHP2$300,665
R01 · FY2014 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$292,761
R01 · FY2014 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$301,815
R01 · FY2013 · CA · contact PI
Small Molecule Inhibitors for the Oncogenic Protein Tyrosine Phosphatase SHP2$291,367
R01 · FY2013 · CA · contact PI
Chemical Genomics$82,641
P30 · FY2013 · CA · contact PI
Chemical Genomics$7,137
P30 · FY2013 · CA · contact PI
Chemical Genomics$5,357
P30 · FY2013 · CA · contact PI
Small Molecule Inhibitors for the Oncogenic Protein Tyrosine Phosphatase SHP2$309,964
R01 · FY2012 · CA · contact PI
Targeting PRL Phosphatases for Cancer Therapy$303,925
R01 · FY2012 · CA · contact PI
Chemical Genomics$68,770
P30 · FY2012 · CA · contact PI
Small Molecule Inhibitors for the Oncogenic Protein Tyrosine Phosphatase SHP2$309,964
R01 · FY2011 · CA · contact PI
Targeting PRL Phosphatases for Cancer Therapy$303,925
R01 · FY2011 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$292,141
R01 · FY2011 · CA · contact PI
Chemical Genomics$73,910
P30 · FY2011 · CA · contact PI
Target Mycobacterium Protein Tyrosine Phosphatase B for Anti-Tuberculosis Agents$406,500
R56 · FY2010 · AI · contact PI
Small Molecule Inhibitors for the Oncogenic Protein Tyrosine Phosphatase SHP2$319,550
R01 · FY2010 · CA · contact PI
Targeting PRL Phosphatases for Cancer Therapy$313,325
R01 · FY2010 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$301,177
R01 · FY2010 · CA · contact PI
Chemical Genomics$88,792
P30 · FY2010 · CA · contact PI
Targeting PRL Phosphatases for Cancer Therapy$313,325
R01 · FY2009 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$301,177
R01 · FY2009 · CA · contact PI
Chemical Genomics$82,721
P30 · FY2009 · CA · contact PI
Targeting PRL Phosphatases for Cancer Therapy$313,931
R01 · FY2008 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$301,759
R01 · FY2008 · CA · contact PI
Chemical Genomics$47,220
P30 · FY2008 · CA · contact PI
Structure/Function of Protein Tyrosine Phosphatases$302,174
R01 · FY2007 · CA · contact PI
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$279,199
R01 · FY2006 · CA · contact PI
Chemical Genetic and Proteomic Analysis of PTP1B$266,292
R01 · FY2006 · DK · contact PI
Chemical Genetic and Proteomic Analysis of PTP1B$272,700
R01 · FY2005 · DK
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$167,768
R01 · FY2005 · CA
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$166,650
R01 · FY2005 · CA
CRYSTAL STRUCTURE OF THE YERSINIA PESTIS PROTEIN TYROSINE PHOSPHATASE YOPH$20,083
P41 · FY2005 · RR
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$334,418
R01 · FY2004 · CA
Chemical Genetic and Proteomic Analysis of PTP1B$295,500
R01 · FY2004 · DK
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$334,418
R01 · FY2003 · CA
YERSINIA PTPASE INHIBITORS AS ANTI-PLAGUE AGENTS$334,000
R01 · FY2003 · AI
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$354,407
R01 · FY2002 · CA
YERSINIA PTPASE INHIBITORS AS ANTI-PLAGUE AGENTS$317,300
R01 · FY2002 · AI
YERSINIA PTPASE INHIBITORS AS ANTI-PLAGUE AGENTS$334,917
R01 · FY2001 · AI
SPECIFICITY OF PROTEIN TYROSINE PHOSPHATASES$225,940
R01 · FY2001 · GM
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$28,793
R01 · FY2001 · CA
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$12,646
R01 · FY2001 · CA
YERSINIA PTPASE INHIBITORS AS ANTI-PLAGUE AGENTS$279,167
R01 · FY2000 · AI
PROTEIN TYROSINE PHOSPHATASES--MECHANISM OF CATALYSIS$263,135
R01 · FY2000 · CA
SPECIFICITY OF PROTEIN TYROSINE PHOSPHATASES$220,785
R01 · FY2000 · GM