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Shengdar Tsai

Massachusetts General Hospital

$7,312,012
Attributed
$9,785,572
Total exposure
7
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2.3M · FY201325
$2.5M$1.9M$1.3M$625K$0
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'20
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'22
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'25

Funding mix

By agency

NIH$9,785,572 · 7

By mechanism

U01$9,678,288 · 6
F32$107,284 · 1

Top collaborators

Most similar at Massachusetts General Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Technology

Research focus

TechnologyGenome EditingSafetyIn VivoGenome-WideAffectTherapeutic Genome EditingGeneticOff-Target MutationCellsGenetic DiseasesHuman GenomeGene TherapySiteHuman DiseaseSafety AssessmentGenomic MedicineProto-OncogenesPharmaceutical PreparationsSickle Cell AnemiaProtocols DocumentationFutureEngineeringManufacture

Grant awards (17)

Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell disease$1,183,000
U01 · FY2025 · HL
Sensitive, unbiased, high-throughput, cellular GUIDE-seq-2 genome-wide activity assay for therapeutic genome editing INDs$479,100
U01 · FY2025 · AI · contact PI
Ultra-sensitive, unbiased, high-throughput, biochemical CHANGE-seq genome-wide activity and gRNA sequencing assays for therapeutic genome editing INDs$479,100
U01 · FY2025 · AI · contact PI
Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell disease$185,000
U01 · FY2025 · HL
Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell disease$1,159,340
U01 · FY2024 · HL
Ultra-sensitive, unbiased, high-throughput, biochemical CHANGE-seq genome-wide activity and gRNA sequencing assays for therapeutic genome editing INDs$479,100
U01 · FY2024 · AI · contact PI
Sensitive, unbiased, high-throughput, cellular GUIDE-seq-2 genome-wide activity assay for therapeutic genome editing INDs$479,100
U01 · FY2024 · AI · contact PI
Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell disease$1,183,000
U01 · FY2023 · HL
Sensitive, unbiased, high-throughput, cellular GUIDE-seq-2 genome-wide activity assay for therapeutic genome editing INDs$479,100
U01 · FY2023 · AI · contact PI
Ultra-sensitive, unbiased, high-throughput, biochemical CHANGE-seq genome-wide activity and gRNA sequencing assays for therapeutic genome editing INDs$479,100
U01 · FY2023 · AI · contact PI
A novel human T-cell platform to define biological effects of genome editing$609,968
U01 · FY2022 · AI · contact PI
A novel human T-cell platform to define biological effects of genome editing$610,061
U01 · FY2021 · AI · contact PI
A novel human T-cell platform to define biological effects of genome editing$610,710
U01 · FY2020 · AI · contact PI
A novel human T-cell platform to define biological effects of genome editing$611,358
U01 · FY2019 · EB · contact PI
A novel human T-cell platform to define biological effects of genome editing$651,251
U01 · FY2018 · HL · contact PI
Improving the Efficiency of Gene Targeting Using TAL Effector Nucleases$55,094
F32 · FY2014 · GM · contact PI
Improving the Efficiency of Gene Targeting Using TAL Effector Nucleases$52,190
F32 · FY2013 · GM · contact PI