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Igor Astsaturov

Fox Chase Cancer Center

$3,975,720
Attributed
$5,075,436
Total exposure
8
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $736.8K · FY201125
$1M$750K$500K$250K$0
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$5,075,436 · 8

By mechanism

R01$2,513,369 · 2
R21$1,781,763 · 4
K22$592,304 · 1
R03$188,000 · 1

Top collaborators

Most similar at Fox Chase Cancer Center

Same institution · by research overlap

Others in their field

Top investigators on “Malignant Neoplasms

Research focus

Malignant NeoplasmsSignal TransductionCellsTumorCancer CellProteinsPathway InteractionsResistanceBasePharmaceutical PreparationsNeoplastic CellLinkSterolsMetabolicMouse ModelCell MembraneGrowthCholesterolMalignant Neoplasm Of PancreasCetuximabBioinformaticsEnzymesIn VivoEpithelial Cells

Grant awards (19)

Targeting anoctamin 6 to disrupt trogocytosis of cancer-associated fibroblasts$642,755
R01 · FY2025 · CA · contact PI
Divergent Functions of ERK2 Substrate Binding Domains in Pathogenesis of KRAS-Driven Pancreatic Cancer$94,000
R03 · FY2025 · CA · contact PI
A Phase I Proof-of-Concept Study of CBL0137 Combined with Ipilimumab and Nivolumab Therapy in Locally Advanced or Metastatic Melanoma$208,738
R21 · FY2024 · CA · contact PI
Divergent Functions of ERK2 Substrate Binding Domains in Pathogenesis of KRAS-Driven Pancreatic Cancer$94,000
R03 · FY2024 · CA · contact PI
A Phase I Proof-of-Concept Study of CBL0137 Combined with Ipilimumab and Nivolumab Therapy in Locally Advanced or Metastatic Melanoma$263,670
R21 · FY2023 · CA · contact PI
Neoadjuvant Stroma Modification in Pancreatic Cancer$249,135
R21 · FY2022 · CA · contact PI
Neoadjuvant Stroma Modification in Pancreatic Cancer$210,508
R21 · FY2021 · CA · contact PI
Oncogenic Synapses: cell-cell contacts enabling trogocytic-based metabolic interactions between pancreatic cancer and fibroblastic stromal cells$200,481
R21 · FY2020 · CA · contact PI
Oncogenic Synapses: cell-cell contacts enabling trogocytic-based metabolic interactions between pancreatic cancer and fibroblastic stromal cells$236,146
R21 · FY2019 · CA · contact PI
Synergistic targeting of cholesterol metabolism and EGFR signaling in cancer$379,725
R01 · FY2018 · CA · contact PI
Synergistic targeting of cholesterol metabolism and EGFR signaling in cancer$379,725
R01 · FY2017 · CA · contact PI
Synergistic targeting of cholesterol metabolism and EGFR signaling in cancer$370,388
R01 · FY2016 · CA · contact PI
Synergistic targeting of cholesterol metabolism and EGFR signaling in cancer$370,388
R01 · FY2015 · CA · contact PI
Synergistic targeting of cholesterol metabolism and EGFR signaling in cancer$370,388
R01 · FY2014 · CA · contact PI
Regulation of EGFR by SC4MOL- and NSDHL-Dependent Trafficking$218,966
R21 · FY2013 · CA · contact PI
Targeting Sterol Gene SC4MOL and EGFR as Synergistic Anti-Cancer Strategy$195,961
K22 · FY2013 · CA · contact PI
Targeting Sterol Gene SC4MOL and EGFR as Synergistic Anti-Cancer Strategy$197,098
K22 · FY2012 · CA · contact PI
Regulation of EGFR by SC4MOL- and NSDHL-Dependent Trafficking$194,119
R21 · FY2012 · CA · contact PI
Targeting Sterol Gene SC4MOL and EGFR as Synergistic Anti-Cancer Strategy$199,245
K22 · FY2011 · CA · contact PI