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Jim Rotolo

Ceramide Therapeutics, Llc

$6,184,744
Attributed
$6,184,744
Total exposure
8
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $2.2M · FY201124
$2.5M$1.9M$1.3M$625K$0
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24

Funding mix

By agency

NIH$6,184,744 · 8

By mechanism

R44$3,429,465 · 2
R43$2,755,279 · 6

Top collaborators

No co-investigators on record.

Others in their field

Top investigators on “In Vivo

Research focus

In VivoDoseIn VitroAffinityMediatingBaseTissuesCessation Of LifeCellsGenesPeptidesDesignCell SurvivalProteinsApoptosisSmall Business Innovation Research GrantMedicalBiological AvailabilityMalignant NeoplasmsMembraneCell DeathGeneticBindingEnzyme-Linked Immunosorbent Assay

Grant awards (14)

Development of a cell-penetrating beta-catenin antagonist peptide as a therapeutic candidate for Wnt-driven breast cancer$632,111
R44 · FY2024 · CA · contact PI
Development of a cell-penetrating beta-catenin antagonist peptide as a therapeutic candidate for Wnt-driven breast cancer$1,362,268
R44 · FY2023 · CA · contact PI
Efficacy and PK/PD of a C/EBP beta antagonist in orthotopic breast cancer$803,479
R44 · FY2023 · CA · contact PI
Efficacy and PK/PD of a C/EBP beta antagonist in orthotopic breast cancer$631,607
R44 · FY2022 · CA · contact PI
Inhibition of SARS-CoV-2 infection with a pan-coronavirus anti-viral peptide$288,178
R43 · FY2022 · AI · contact PI
Development of a cell-penetrating beta-catenin antagonist peptide as a therapeutic candidate for Wnt-driven breast cancer$409,295
R43 · FY2021 · CA · contact PI
Inhibition of SARS-CoV-2 infection with a pan-coronavirus anti-viral peptide$299,860
R43 · FY2021 · AI · contact PI
Efficacy and PK/PD of a C/EBP beta antagonist in orthotopic breast cancer$255,240
R43 · FY2020 · CA · contact PI
Single-chain antibody countermeasures for the Radiation GI Syndrome$101,021
R43 · FY2015 · AI · contact PI
Single-chain antibody countermeasures for the Radiation GI Syndrome$300,000
R43 · FY2014 · AI · contact PI
Neutralization of ceramide as a novel approach to specifically inhibit acute GvHD$223,891
R43 · FY2013 · AI · contact PI
Selection of an anti-ceramide mitigator of acute radiation toxicity of the GI tra$292,977
R43 · FY2012 · AI · contact PI
Neutralization of ceramide as a novel approach to specifically inhibit acute GvHD$284,820
R43 · FY2012 · AI · contact PI
Selection of an anti-ceramide mitigator of acute radiation toxicity of the GI tra$299,997
R43 · FY2011 · AI · contact PI