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Joseph R Mazzulli

Massachusetts General Hospital

$12,420,744
Attributed
$12,741,948
Total exposure
9
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2.8M · FY200925
$5M$3.8M$2.5M$1.3M$0
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$12,741,948 · 9

By mechanism

R01$7,004,299 · 2
RF1$1,928,426 · 1
R61$1,707,089 · 1
R21$1,309,000 · 3
R56$642,408 · 1
F32$150,726 · 1

Top collaborators

Most similar at Massachusetts General Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Pathway Interactions

Research focus

Pathway InteractionsBrainParkinson DiseaseProteinsNeuronsFunctional DisorderTraffickingCellsSynucleinopathyAlpha SynucleinIn VivoInduced Pluripotent Stem CellNeurotoxicityNovel TherapeuticsNerve DegenerationProtein TransportProtein AggregationMutationLeadLinkProteostasisPlayNeurodegenerative DisordersPathogenicity

Grant awards (26)

The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$618,542
R01 · FY2025 · NS · contact PI
Synergistic Enhancement of ER proteostasis, trafficking, and lysosomes as treatments for Dementia with Lewy bodies and Parkinson’s disease-dementia$1,707,089
R61 · FY2024 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$618,542
R01 · FY2024 · NS · contact PI
Mechanisms of gene regulation and RNA processing in synucleinopathies$521,938
R01 · FY2024 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$618,542
R01 · FY2023 · NS · contact PI
Mechanisms of gene regulation and RNA processing in synucleinopathies$521,938
R01 · FY2023 · NS · contact PI
Exploring the Pathogenic Mechanisms of Batten's disease MFSD8 mutations using patient iPSC derived neurons.$200,000
R21 · FY2023 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$618,542
R01 · FY2022 · NS · contact PI
Mechanisms of gene regulation and RNA processing in synucleinopathies$521,938
R01 · FY2022 · NS · contact PI
Exploring the Pathogenic Mechanisms of Batten's disease MFSD8 mutations using patient iPSC derived neurons.$240,000
R21 · FY2022 · NS · contact PI
Examining the role of phosphatidylethanolamine and autophagic disruption in Lewy Body Dementias and Parkinson's disease$642,408
R56 · FY2021 · NS
Mechanisms of gene regulation and RNA processing in synucleinopathies$615,591
R01 · FY2021 · NS · contact PI
Mechanisms of gene regulation and RNA processing in synucleinopathies$658,881
R01 · FY2020 · NS · contact PI
Examining the role of glycosphingolipids in the progression and heterogeneity of synucleinopathies$1,928,426
RF1 · FY2019 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$337,969
R01 · FY2019 · NS · contact PI
The effects of a-synuclein accumulation on proteome composition, stability and aggregation$197,500
R21 · FY2019 · NS · contact PI
Exploring the role of protein farnesylation in the regulation of SNARE protein ykt6 in synucleinopathy models$197,500
R21 · FY2019 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$337,969
R01 · FY2018 · NS · contact PI
Exploring the role of protein farnesylation in the regulation of SNARE protein ykt6 in synucleinopathy models$237,000
R21 · FY2018 · NS · contact PI
The effects of a-synuclein accumulation on proteome composition, stability and aggregation$237,000
R21 · FY2018 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$337,969
R01 · FY2017 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$337,969
R01 · FY2016 · NS · contact PI
The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function$337,969
R01 · FY2015 · NS · contact PI
Mechanisms of Mutant Huntington Clearance by Autophagy$53,042
F32 · FY2011 · NS · contact PI
Mechanisms of Mutant Huntington Clearance by Autophagy$50,474
F32 · FY2010 · NS · contact PI
Mechanisms of Mutant Huntington Clearance by Autophagy$47,210
F32 · FY2009 · NS · contact PI