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Michael Ashley Spies
University Of Illinois At Urbana-Champaign
$4,943,885
Attributed
$5,139,256
Total exposure
5
Grants
4
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $624.1K · FY2009–25$1M$750K$500K$250K$0
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$5,139,256 · 5
By mechanism
R01$3,907,266 · 2
R21$824,240 · 2
R35$407,750 · 1
Top collaborators
- Maria Spies2 shared
Most similar at University Of Illinois At Urbana-Champaign
Same institution · by research overlap
- John A Gerlt$49,592,476
Others in their field
Top investigators on “Structure”
- David Heimbrook · Leidos Biomedical Research, Inc.$475,333,582
- Barton F Haynes · Duke University$444,977,767
- Lawrence Corey · Fred Hutchinson Cancer Center$334,646,086
- Gary D Acton · University Of California-Davis$320,373,312
- Mitchell J Malone · Texas A&M Research Foundation$320,373,312
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$315,257,203
Research focus
StructurePharmaceutical PreparationsSmall MoleculeDrug DiscoveryEnzymesFlexibilityDrug TargetingPropertyBaseComplexBindingInhibitor/AntagonistFamilyAntimicrobialDesignSourceGlutamate RacemaseAntimicrobial DrugPublishingLigandsBiophysicsProteinsReactionHybrids
Grant awards (19)
Allosteric Control: Establishing the Nexus of Structure and Catalytic Power$407,750
R35 · FY2025 · GM · contact PI
Natural products inhibitors targeting homology-directed DNA repair for cancer therapy$172,653
R21 · FY2024 · CA
Dialing down caspase-7 through allosteric control: An integrated approach$309,000
R01 · FY2023 · GM · contact PI
Natural products inhibitors targeting homology-directed DNA repair for cancer therapy$218,089
R21 · FY2023 · CA
Dialing down caspase-7 through allosteric control: An integrated approach$309,000
R01 · FY2022 · GM · contact PI
Dialing down caspase-7 through allosteric control: An integrated approach$309,000
R01 · FY2021 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$315,141
R01 · FY2020 · GM · contact PI
Dialing down caspase-7 through allosteric control: An integrated approach$309,000
R01 · FY2020 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$308,577
R01 · FY2019 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$308,577
R01 · FY2018 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$40,000
R01 · FY2018 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$308,577
R01 · FY2017 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$280,039
R01 · FY2016 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$280,039
R01 · FY2015 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$280,039
R01 · FY2014 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$270,238
R01 · FY2013 · GM · contact PI
Exploiting Enzyme Plasticity in Drug Discovery: application to glutamate racemase$280,039
R01 · FY2012 · GM · contact PI
Determination of the Biological Roles and Chemical Mechanisms of the Glutamate Ra$235,373
R21 · FY2010 · AI · contact PI
Determination of the Biological Roles and Chemical Mechanisms of the Glutamate Ra$198,125
R21 · FY2009 · AI · contact PI