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Pamela J Lein

University Of California At Davis

$34,968,069
Attributed
$54,397,226
Total exposure
33
Grants
23
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $10M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$101,727,717 · 35

By mechanism

U54$62,770,756 · 10
R01$24,030,947 · 9
RF1$7,473,409 · 3
R21$3,542,649 · 8
T32$2,812,399 · 1
P30$793,402 · 2

Most similar at University Of California At Davis

Same institution · by research overlap

Others in their field

Top investigators on “Brain

Research focus

BrainExposure ToDoseRattusBaseLinkAlzheimer&AposIntoxicationResponseAcuteFemaleMaleBehavioralMolecularMonitorNeurologicSeizuresUnited States National Institutes Of HealthNeuroinflammationNeuronsNeuropathologyIn VivoCognitiveAnimals

Grant awards (153)

UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$2,762,691
U54 · FY2025 · NS · contact PI
Do Atmospheric Ultrafine Particles Lodge in the Brain and Cause Cognitive Decline Leading to Alzheimer's Disease Related Dementias?$760,707
R01 · FY2025 · NS · contact PI
Traffic-related air pollution exacerbates AD-relevant phenotypes in a genetically susceptible rat model via neuroinflammatory mechanism(s)$745,652
R01 · FY2025 · AG · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$610,185
R01 · FY2025 · ES · contact PI
Administrative Core$345,337
U54 · FY2025 · NS · contact PI
Project 1: Reduction of Pro-Inflammatory Signaling$345,336
U54 · FY2025 · NS · contact PI
Administrative Core$160,994
U54 · FY2025 · NS · contact PI
Long-Term Consequences of Acute Organophosphate Intoxication in an Adolescent Rodent Model$160,994
U54 · FY2025 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$114,992
R01 · FY2025 · ES · contact PI
Traffic-related air pollution exacerbates AD-relevant phenotypes in a genetically susceptible rat model via neuroinflammatory mechanism(s)$95,170
R01 · FY2025 · AG · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$95,141
R01 · FY2025 · ES · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$73,749
U54 · FY2025 · NS · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$73,749
U54 · FY2025 · NS · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$2,770,046
U54 · FY2024 · NS · contact PI
Traffic-related air pollution exacerbates AD-relevant phenotypes in a genetically susceptible rat model via neuroinflammatory mechanism(s)$768,902
R01 · FY2024 · AG · contact PI
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?$619,202
R01 · FY2024 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$611,064
R01 · FY2024 · ES · contact PI
Project 1: Reduction of Pro-Inflammatory Signaling$491,473
U54 · FY2024 · NS · contact PI
Administrative Core$434,877
U54 · FY2024 · NS · contact PI
Diversity Supplement to Molecular and Cellular Basis of PCB Developmental Neurotoxicity$97,382
R01 · FY2024 · ES · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$88,497
U54 · FY2024 · NS · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$88,497
U54 · FY2024 · NS · contact PI
Diversity Supplement toTraffic-related air pollution exacerbates AD-relevant phenotypes in a genetically susceptible rat model via neuroinflammatory mechanism(s)$71,377
R01 · FY2024 · AG · contact PI
Diversity Supplement to Molecular and Cellular Basis of PCB Developmental Neurotoxicity (Mendieta)$21,619
R01 · FY2024 · ES · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$2,729,988
U54 · FY2023 · NS · contact PI
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?$619,202
R01 · FY2023 · ES
Project 1: Reduction of Pro-Inflammatory Signaling$491,094
U54 · FY2023 · NS · contact PI
Administrative Core$432,069
U54 · FY2023 · NS · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$88,497
U54 · FY2023 · NS · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$88,497
U54 · FY2023 · NS · contact PI
Diversity Supplement to UC Davis CounterACT Center of Excellence: The role of the JAK/STAT signaling pathway in chronic neurological effects of acute organophosphate intoxication$14,751
U54 · FY2023 · NS · contact PI
Diversity Supplement to UC Davis CounterACT Center of Excellence: Role of IL-1β in mediating the chronic adverse neurological effects of acute organophosphate intoxication.$14,751
U54 · FY2023 · NS · contact PI
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication$2,713,427
U54 · FY2022 · NS · contact PI
Do Atmospheric Ultrafine Particles Lodge in the Brain and Cause Cognitive Decline Leading to Alzheimer's Disease Related Dementias?$2,094,256
RF1 · FY2022 · NS · contact PI
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?$620,458
R01 · FY2022 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$612,589
R01 · FY2022 · ES · contact PI
Project 1: Reduction of Pro-Inflammatory Signaling$492,016
U54 · FY2022 · NS · contact PI
PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)$462,951
R01 · FY2022 · ES
Administrative Core$430,719
U54 · FY2022 · NS · contact PI
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication$3,649,220
U54 · FY2021 · NS · contact PI
Traffic-related air pollution exacerbates AD-relevant phenotypes in a genetically susceptible rat model via neuroinflammatory mechanism(s)$2,293,425
RF1 · FY2021 · AG · contact PI
Mitigation of Neurological Damage Following Seizures$1,016,569
U54 · FY2021 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$642,317
R01 · FY2021 · ES · contact PI
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?$621,086
R01 · FY2021 · ES
PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)$472,999
R01 · FY2021 · ES
Administrative Core$274,750
U54 · FY2021 · NS · contact PI
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication$3,778,502
U54 · FY2020 · NS · contact PI
Mitigation of Neurological Damage Following Seizures$1,019,174
U54 · FY2020 · NS · contact PI
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?$644,712
R01 · FY2020 · ES
PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)$484,252
R01 · FY2020 · ES
Ketogenic diet approaches to slow disease progression in a rat model of Alzheimer's disease$431,750
R21 · FY2020 · AG
Inhibiting AD Inflammation with a Novel Class of Small Molecule PAI-1 Antagonists$431,750
R21 · FY2020 · AG · contact PI
Administrative Core$274,750
U54 · FY2020 · NS · contact PI
Identifying Molecular Targets for the Proconvulsant Activity of TETS$186,958
R21 · FY2020 · NS · contact PI
Imaging biomarkers of early synaptic changes in a preclinical model of Alzheimer’s disease$157,000
R21 · FY2020 · AG
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication$3,781,279
U54 · FY2019 · NS · contact PI
Mitigation of Neurological Damage Following Seizures$1,023,165
U54 · FY2019 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$936,611
R01 · FY2019 · ES · contact PI
PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)$491,228
R01 · FY2019 · ES
Advanced Training in Environmental Health Sciences$318,522
T32 · FY2019 · ES · contact PI
Administrative Core$274,750
U54 · FY2019 · NS · contact PI
Imaging biomarkers of early synaptic changes in a preclinical model of Alzheimer’s disease$274,750
R21 · FY2019 · AG
Identifying Molecular Targets for the Proconvulsant Activity of TETS$227,053
R21 · FY2019 · NS · contact PI
Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES) Admin Supplement$157,000
R01 · FY2019 · ES
CounterACT 2020 Annual Meeting$150,000
U54 · FY2019 · NS · contact PI
Career Development Core$133,370
P30 · FY2019 · ES · contact PI
Vascular Inflammation and Exosomes as Mediators in Aging and Dementia$93,978
RF1 · FY2019 · AG
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication$3,785,164
U54 · FY2018 · NS · contact PI
Vascular Inflammation and Exosomes as Mediators in Aging and Dementia$2,991,750
RF1 · FY2018 · AG
Mitigation of Neurological Damage Following Seizures$1,028,186
U54 · FY2018 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$510,293
R01 · FY2018 · ES · contact PI
PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)$501,836
R01 · FY2018 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity: ViCTER supplement$441,829
R01 · FY2018 · ES · contact PI
Advanced Training in Environmental Health Sciences$315,351
T32 · FY2018 · ES · contact PI
Administrative Core$274,750
U54 · FY2018 · NS · contact PI
Career Development Core$133,370
P30 · FY2018 · ES · contact PI
Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication$3,757,156
U54 · FY2017 · NS · contact PI
Mitigation of Neurological Damage Following Seizures$1,009,688
U54 · FY2017 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$514,963
R01 · FY2017 · ES · contact PI
Administrative Core$274,750
U54 · FY2017 · NS · contact PI
Does air pollution increase risk of AD in a genetically susceptible animal model?$196,250
R21 · FY2017 · ES · contact PI
Advanced Training in Environmental Health Sciences$187,032
T32 · FY2017 · ES · contact PI
Career Development Core$133,369
P30 · FY2017 · ES · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$3,282,801
U54 · FY2016 · NS · contact PI
Mitigation of neurological damage following seizures$905,229
U54 · FY2016 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$509,395
R01 · FY2016 · ES · contact PI
Does air pollution increase risk of AD in a genetically susceptible animal model?$235,438
R21 · FY2016 · ES · contact PI
Advanced Training in Environmental Health Sciences$228,894
T32 · FY2016 · ES · contact PI
Administrative Core$194,732
U54 · FY2016 · NS · contact PI
Career Development Core$133,127
P30 · FY2016 · ES · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$3,280,585
U54 · FY2015 · NS · contact PI
Mitigation of neurological damage following seizures$902,694
U54 · FY2015 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$522,199
R01 · FY2015 · ES · contact PI
Advanced Training in Environmental Health Sciences$224,860
T32 · FY2015 · ES · contact PI
Administrative Core$198,170
U54 · FY2015 · NS · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$154,722
U54 · FY2015 · NS · contact PI
Career Development Core$132,733
P30 · FY2015 · ES · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$130,000
U54 · FY2015 · NS · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$3,272,806
U54 · FY2014 · NS · contact PI
Mitigation of neurological damage following seizures$906,734
U54 · FY2014 · NS · contact PI
Enantioselective Metabolism Influences PCB Developmental Neurotoxicity$403,007
R01 · FY2014 · ES
Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity$339,605
R01 · FY2014 · ES · contact PI
Advanced Training in Environmental Health Sciences$223,062
T32 · FY2014 · ES · contact PI
Administrative Core$193,157
U54 · FY2014 · NS · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$77,127
U54 · FY2014 · NS · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$41,000
U54 · FY2014 · NS · contact PI
Administrative Core$9,641
U54 · FY2014 · NS · contact PI
Mitigation of neurological damage following seizures$9,641
U54 · FY2014 · NS · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$3,329,807
U54 · FY2013 · NS · contact PI
Mitigation of neurological damage following seizures$823,241
U54 · FY2013 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$449,985
R01 · FY2013 · ES · contact PI
Enantioselective Metabolism Influences PCB Developmental Neurotoxicity$398,936
R01 · FY2013 · ES
Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity$336,175
R01 · FY2013 · ES · contact PI
Advanced Training in Environmental Health Sciences$219,105
T32 · FY2013 · ES · contact PI
Administrative Core$187,072
U54 · FY2013 · NS · contact PI
Novel anticonvulsant and neuroprotective therapies for TETS and OP intoxication$3,192,188
U54 · FY2012 · NS · contact PI
Mitigation of neurological damage following seizures$827,221
U54 · FY2012 · NS · contact PI
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$458,921
R01 · FY2012 · ES · contact PI
Enantioselective Metabolism Influences PCB Developmental Neurotoxicity$407,078
R01 · FY2012 · ES
Advanced Training Environmental Health Sciences$370,951
T32 · FY2012 · ES · contact PI
Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity$342,943
R01 · FY2012 · ES · contact PI
Administrative Core$188,286
U54 · FY2012 · NS · contact PI
Biomarkers of Organophosphorus Pesticide-Induced Neurotoxicity$667,182
R01 · FY2011 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$468,190
R01 · FY2011 · ES · contact PI
Enantioselective Metabolism Influences PCB Developmental Neurotoxicity$407,078
R01 · FY2011 · ES
Identification of novel therapeutic approaches for TETS and OP intoxication$383,750
R21 · FY2011 · NS · contact PI
Advanced Training Environmental Health Sciences$364,428
T32 · FY2011 · ES · contact PI
Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity$342,386
R01 · FY2011 · ES · contact PI
Biomarkers of Organophosphorus Pesticide-Induced Neurotoxicity$659,106
R01 · FY2010 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$474,003
R01 · FY2010 · ES · contact PI
Enantioselective Metabolism Influences PCB Developmental Neurotoxicity$423,869
R01 · FY2010 · ES
Identification of novel therapeutic approaches for TETS and OP intoxication$382,813
R21 · FY2010 · NS · contact PI
Advanced Training Environmental Health Sciences$360,194
T32 · FY2010 · ES · contact PI
Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity$358,625
R01 · FY2010 · ES · contact PI
Enantioselective Metabolism Influences PCB Developmental Neurotoxicity$9,405
R01 · FY2010 · ES
Biomarkers of Organophosphorus Pesticide-Induced Neurotoxicity$599,223
R01 · FY2009 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$460,123
R01 · FY2009 · ES · contact PI
Biomarkers of Organophosphorus Pesticide-Induced Neurotoxicity$62,486
R01 · FY2009 · ES
Biomarkers of Organophosphorus Pesticide-Induced Neurotoxicity$576,936
R01 · FY2008 · ES
Molecular and Cellular Basis of PCB Developmental Neurotoxicity$150,000
R56 · FY2007 · ES · contact PI
CORE--CELL AND TISSUE ANALYSIS$127,433
P30 · FY2007 · ES · contact PI
Retrograde Dystrophic Influence of IFN-gamma on Neurons$242,580
R01 · FY2006 · NS · contact PI
Retrograde Dystrophic Influence of IFN-gamma on Neurons$248,417
R01 · FY2005 · NS
Molecular Regulation of Primary Dendritogenesis$151,023
R21 · FY2005 · NS
Retrograde Dystrophic Influence of IFN-gamma on Neurons$248,417
R01 · FY2004 · NS
Molecular Regulation of Primary Dendritogenesis$163,773
R21 · FY2004 · NS
Retrograde Dystrophic Influence of IFN-gamma on Neurons$268,958
R01 · FY2003 · NS
Mechanism of organophosphate development neurotoxicity$100,548
R21 · FY2003 · ES
Mechanism of organophosphate development neurotoxicity$62,643
R21 · FY2003 · ES
Do PCBs alter developing brain structure and cognition?$51,524
R03 · FY2003 · HD
Do PCBs alter developing brain structure and cognition?$25,961
R03 · FY2003 · HD
Mechanism of organophosphate development neurotoxicity$157,150
R21 · FY2002 · ES
Do PCBs alter developing brain structure and cognition?$76,670
R03 · FY2002 · HD