← Leaderboards
Randal J. Kaufman
Indiana University Indianapolis
$37,816,764
Attributed
$44,580,747
Total exposure
25
Grants
21
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $4.5M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$49,280,857 · 26
By mechanism
R01$27,414,182 · 9
P01$11,171,540 · 8
R37$4,921,084 · 1
R24$4,576,650 · 2
S10$600,000 · 1
R21$466,538 · 1
Top collaborators
- Peter Arvan7 shared
- Pamela Rose Itkin-Ansari6 shared
- Timothy Yikai Huang4 shared
- Dieter A Wolf2 shared
- Huaxi Xu1 shared
Most similar at Indiana University Indianapolis
Same institution · by research overlap
- Ronald C Wek$16,092,740
- Sarath Chandra Janga$2,216,292
Others in their field
Top investigators on “Endoplasmic Reticulum”
- Ralph Parchment · Leidos Biomedical Research, Inc.$25,266,647
- Peter Arvan · University Of Michigan At Ann Arbor$23,625,830
- Feroz R Papa · University Of California San Francisco$18,595,073
- Zihai Li · Ohio State University$17,028,405
- J. Kevin Kevin Foskett · University Of Pennsylvania$16,942,170
- David H Perlmutter · Washington University$16,118,234
Research focus
Endoplasmic ReticulumProteinsResponseInsightProductionProtein FoldingPathway InteractionsProtein MisfoldingGeneticCellsSignal TransductionMouse ModelMediatingPreventMolecular ChaperonesCell DeathLinkProtein BiosynthesisAttenuatedGrantGenesPhosphorylationEndoplasmic Reticulum StressCell Physiology
Grant awards (95)
Role of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC)$2,302,833
P01 · FY2025 · CA · contact PI
Improving Proinsulin Folding to Ameliorate Type II Diabetes$760,498
R01 · FY2025 · DK · contact PI
Overcoming FVIII protein misfolding and cell toxicity$472,398
P01 · FY2025 · HL · contact PI
Project 2: The UPR transducer ATF6 drives HCC in response to metabolic stress$222,367
P01 · FY2025 · CA · contact PI
Core A: Administrative Core$43,974
P01 · FY2025 · CA · contact PI
Role of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC)$2,397,277
P01 · FY2024 · CA · contact PI
Improving Proinsulin Folding to Ameliorate Type II Diabetes$730,079
R01 · FY2024 · DK · contact PI
Project 2: The UPR transducer ATF6 drives HCC in response to metabolic stress$681,823
P01 · FY2024 · CA · contact PI
Overcoming FVIII protein misfolding and cell toxicity$519,290
P01 · FY2024 · HL · contact PI
Core A: Administrative Core$134,831
P01 · FY2024 · CA · contact PI
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"$974,957
R01 · FY2023 · AG · contact PI
Improving Proinsulin Folding to Ameliorate Type II Diabetes$809,598
R01 · FY2023 · DK · contact PI
Acquisition of Zeiss LSM980 with Airyscan 2, a super-resolution point scanning confocal microscope$600,000
S10 · FY2023 · OD · contact PI
Overcoming FVIII protein misfolding and cell toxicity$576,990
P01 · FY2023 · HL · contact PI
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"$974,758
R01 · FY2022 · AG · contact PI
Overcoming FVIII protein misfolding and cell toxicity$585,948
P01 · FY2022 · HL · contact PI
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"$971,032
R01 · FY2021 · AG · contact PI
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"$973,393
R01 · FY2020 · AG · contact PI
ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinoma$647,740
R01 · FY2020 · CA · contact PI
Mechanism of ER Protein Misfolding-Induced Mitochondrial Dysfunction$614,427
R01 · FY2020 · DK · contact PI
Modifiers of Proinsulin Influence T2D Susceptibility$1,008,830
R24 · FY2019 · DK · contact PI
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"$941,795
R01 · FY2019 · AG · contact PI
ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinoma$640,385
R01 · FY2019 · CA · contact PI
Mechanism of ER Protein Misfolding-Induced Mitochondrial Dysfunction$614,427
R01 · FY2019 · DK · contact PI
Homeostatic Role of IRE1a-XBP1-PDI1 in Hepatic Lipid Metabolism$585,000
R01 · FY2019 · DK · contact PI
Modifiers of Proinsulin Influence T2D Susceptibility$1,008,830
R24 · FY2018 · DK · contact PI
ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinoma$668,490
R01 · FY2018 · CA · contact PI
Mechanism of ER protein misfolding-induced mitochondrial dysfunction$614,427
R01 · FY2018 · DK · contact PI
Homeostatic role of IRE1a-XBP1-PDI1 in hepatic lipid metabolism$585,000
R01 · FY2018 · DK · contact PI
Modifiers of Proinsulin Influence T2D Susceptibility$1,008,830
R24 · FY2017 · DK · contact PI
ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinoma$707,261
R01 · FY2017 · CA · contact PI
Mechanism of ER protein misfolding-induced mitochondrial dysfunction$614,427
R01 · FY2017 · DK · contact PI
Homeostatic role of IRE1a-XBP1-PDI1 in hepatic lipid metabolism$585,000
R01 · FY2017 · DK · contact PI
Modifiers of Proinsulin Influence T2D Susceptibility$1,032,580
R24 · FY2016 · DK · contact PI
ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinoma$765,053
R01 · FY2016 · CA · contact PI
Homeostatic role of IRE1a-XBP1-PDI1 in hepatic lipid metabolism$585,000
R01 · FY2016 · DK · contact PI
Role of the Unfolded Protein Response in Beta Cell$543,990
R37 · FY2016 · DK · contact PI
eIF2a phosphorylation as a novel druggable target in CRPC$212,063
R21 · FY2016 · CA
Homeostatic role of IRE1a-XBP1-PDI1 in hepatic lipid metabolism$585,000
R01 · FY2015 · DK · contact PI
Role of the Unfolded Protein Response in Beta Cell$580,221
R37 · FY2015 · DK · contact PI
eIF2a phosphorylation as a novel druggable target in CRPC$254,475
R21 · FY2015 · CA
Regulation of Factor FVIII Secretion$818,084
R01 · FY2014 · HL · contact PI
Regulation of ER stress-induced cell death$663,805
R01 · FY2014 · DK · contact PI
Role of the Unfolded Protein Response in Beta Cell$543,990
R37 · FY2014 · DK · contact PI
Role of the Unfolded Protein Response in Beta Cell$36,231
R37 · FY2014 · DK · contact PI
Regulation of Factor FVIII Secretion$794,710
R01 · FY2013 · HL · contact PI
Regulation of ER stress-induced cell death$563,044
R01 · FY2013 · DK · contact PI
Role of the Unfolded Protein Response in Beta Cell$524,951
R37 · FY2013 · DK · contact PI
How does FVIII Expression Induce Cell Death$282,436
P01 · FY2013 · HL · contact PI
Regulation of ER stress-induced cell death$74,295
R01 · FY2013 · DK · contact PI
Regulation of Factor FVIII Secretion$834,779
R01 · FY2012 · HL · contact PI
Role of the Unfolded Protein Response in Beta Cell$585,755
R37 · FY2012 · DK · contact PI
Regulation of ER stress-induced cell death$583,465
R01 · FY2012 · DK · contact PI
How does FVIII Expression Induce Cell Death$299,492
P01 · FY2012 · HL · contact PI
Regulation of Factor FVIII Secretion$817,884
R01 · FY2011 · HL · contact PI
Regulation of ER stress-induced cell death$556,040
R01 · FY2011 · DK · contact PI
Alteration in protein interactions with proinsulin and insulin in type 2 diabetes$517,580
R24 · FY2011 · DK · contact PI
Role of the Unfolded Protein Response in Beta Cell$498,843
R37 · FY2011 · DK · contact PI
How does FVIII Expression Induce Cell Death$366,177
P01 · FY2011 · HL · contact PI
Regulation of ER stress-induced cell death$619,376
R01 · FY2010 · DK · contact PI
Regulation of Factor VIII Secretion$402,912
R01 · FY2010 · HL · contact PI
Role of the Unfolded Protein Response in Beta Cell$385,751
R37 · FY2010 · DK · contact PI
How does FVIII Expression Induce Cell Death$383,664
P01 · FY2010 · HL · contact PI
Role of the Unfolded Protein Response in Beta Cell$271,091
R37 · FY2010 · DK · contact PI
HTP chemical genomic screens to identify positive regulators of the Unfolded Prot$38,239
R03 · FY2010 · MH · contact PI
Role of the Unfolded Protein Response in Beta Cell$1
R37 · FY2010 · DK · contact PI
Regulation of Factor VIII Secretion$399,164
R01 · FY2009 · HL · contact PI
How does FVIII Expression Induce Cell Death$383,664
P01 · FY2009 · HL · contact PI
Role of the Unfolded Protein Response in Beta Cell$314,613
R37 · FY2009 · DK · contact PI
HTP chemical genomic screens to identify positive regulators of the Unfolded Prot$38,625
R03 · FY2009 · MH · contact PI
Regulation of Factor VIII Secretion$379,783
R01 · FY2008 · HL · contact PI
Role of the Unfolded Protein Response in Beta Cell$314,613
R37 · FY2008 · DK · contact PI
High Throughput Chemical Genomics to Identify Novel Inhibitors of CHOP$24,999
R03 · FY2008 · MH · contact PI
Regulation of Factor VIII Secretion$354,537
R01 · FY2007 · HL · contact PI
Role of the Unfolded Protein Response in Beta Cell$321,034
R37 · FY2007 · DK · contact PI
Role of coagulation Factor VIII in Thrombosis in vivo$304,449
P01 · FY2007 · HL · contact PI
Unfolded proteins in the Endoplasmic Reticulum to Disease$17,000
R13 · FY2007 · DK · contact PI
Regulation of Factor VIII Secretion$355,692
R01 · FY2006 · HL · contact PI
Role of coagulation Factor VIII in Thrombosis in vivo$296,903
P01 · FY2006 · HL · contact PI
Unfolded Protein Response in Glucose Homeostasis$286,622
R01 · FY2006 · DK · contact PI
Regulation of Factor VIII Secretion$339,750
R01 · FY2005 · HL
Unfolded Protein Response in Glucose Homeostasis$295,953
R01 · FY2005 · DK
Role of coagulation Factor VIII in Thrombosis in vivo$288,255
P01 · FY2005 · HL
Regulation of Factor VIII Secretion$339,750
R01 · FY2004 · HL
Unfolded Protein Response in Glucose Homeostasis$296,802
R01 · FY2004 · DK
Role of coagulation Factor VIII in Thrombosis in vivo$279,860
P01 · FY2004 · HL
Unfolded Protein Response in Glucose Homeostasis$343,526
R01 · FY2003 · DK
Regulation of Factor VIII Secretion$339,750
R01 · FY2003 · HL
Conformational Diseases of the Secretory Pathway$12,000
R13 · FY2003 · DK
Regulation of Factor VIII Secretion$332,100
R01 · FY2002 · HL
TRANSLATIONAL CONTROL IN REGULATION OF APOPTOSIS$231,908
R01 · FY2002 · AI
TRANSLATIONAL CONTROL IN REGULATION OF APOPTOSIS$224,801
R01 · FY2001 · AI
MOLECULAR BASIS FOR HEMOPHILIA--DEFECTS IN COFACTOR BIOSYNTHESIS$135,852
P01 · FY2001 · HL
TRANSLATIONAL CONTROL IN REGULATION OF APOPTOSIS$217,903
R01 · FY2000 · AI
MOLECULAR BASIS FOR HEMOPHILIA--DEFECTS IN COFACTOR BIOSYNTHESIS$213,057
P01 · FY2000 · HL