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Steven F Ziegler

Seattle Children'S Hospital

$41,989,753
Attributed
$50,801,447
Total exposure
41
Grants
30
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $5.8M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$73,444,666 · 43

By mechanism

R01$37,200,597 · 17
P01$16,088,932 · 3
U19$12,699,377 · 6
R21$5,695,957 · 12
R56$894,500 · 2
S10$409,200 · 1

Top collaborators

Others in their field

Top investigators on “Cells

Research focus

CellsResponseCytokineInflammationRegulationInflammatoryMediatingPlayInsightImmune ResponseCd4 Positive T LymphocytesEpithelial CellsT-LymphocytePathway InteractionsMouse ModelProductionAntigensMindImmuneSignal TransductionAsthmaLinkLungEpithelial

Grant awards (159)

Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodeling$838,670
R01 · FY2025 · AI
Regulatory T cells maintain immune homeostasis through translation control$831,400
R01 · FY2025 · AI · contact PI
Foxp3 isoform expression and regulation of autoantibody production$709,019
R01 · FY2025 · AI · contact PI
Regulatory T cells maintain immune homeostasis through translation control$888,447
R01 · FY2024 · AI · contact PI
Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodeling$860,375
R01 · FY2024 · AI
Foxp3 isoforms and IgE-mediated UVB-induced skin inflammation expression$216,625
R21 · FY2024 · AI · contact PI
Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodeling$863,906
R01 · FY2023 · AI
Foxp3 isoforms and IgE-mediated UVB-induced skin inflammation expression$259,950
R21 · FY2023 · AI · contact PI
Regulation of Tfh function in autoimmunity by TSLP$216,625
R21 · FY2023 · AI · contact PI
Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodeling$919,436
R01 · FY2022 · AI
Targeting the IL-2/regulatory T cell axis for autoimmune disease prevention in realistic animal models$679,264
R01 · FY2022 · AI
Regulation of Tfh function in autoimmunity by TSLP$259,451
R21 · FY2022 · AI · contact PI
Foxp3DEx2 isoform expression leads to Treg dysfunction and SLE$217,625
R21 · FY2022 · AI · contact PI
Targeting the IL-2/regulatory T cell axis for autoimmune disease prevention in realistic animal models$679,264
R01 · FY2021 · AI
Foxp3DEx2 isoform expression leads to Treg dysfunction and SLE$261,150
R21 · FY2021 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$1,585,668
U19 · FY2020 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$924,424
U19 · FY2020 · AI · contact PI
Targeting the IL-2/regulatory T cell axis for autoimmune disease prevention in realistic animal models$679,264
R01 · FY2020 · AI
IL-33 and food allergy$566,296
R01 · FY2020 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$432,416
U19 · FY2020 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$329,227
U19 · FY2020 · AI · contact PI
Translational Reprogramming by Regulatory T Cells$213,875
R21 · FY2020 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$197,489
U19 · FY2020 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$85,778
U19 · FY2020 · AI · contact PI
Core A: Administrative Core$50,433
U19 · FY2020 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$1,587,982
U19 · FY2019 · AI · contact PI
Targeting the IL-2/regulatory T cell axis for autoimmune disease prevention in realistic animal models$679,264
R01 · FY2019 · AI
IL-33 and food allergy$566,296
R01 · FY2019 · AI · contact PI
A FOXP3 complex that controls human regulatory T cell function$424,500
R01 · FY2019 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$418,848
U19 · FY2019 · AI · contact PI
Translational Reprogramming by Regulatory T Cells$272,888
R21 · FY2019 · AI · contact PI
Core A: Administrative Core$43,302
U19 · FY2019 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$1,588,836
U19 · FY2018 · AI · contact PI
Targeting the IL-2/regulatory T cell axis for autoimmune disease prevention in realistic animal models$679,264
R01 · FY2018 · AI
IL-33 and food allergy$566,296
R01 · FY2018 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$443,934
U19 · FY2018 · AI · contact PI
A FOXP3 complex that controls human regulatory T cell function$424,500
R01 · FY2018 · AI · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$362,503
R01 · FY2018 · CA · contact PI
Generating tolerance to antibody-based drugs$212,500
R21 · FY2018 · AI · contact PI
Core A: Administrative Core$53,813
U19 · FY2018 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$1,591,050
U19 · FY2017 · AI · contact PI
IL-33 and food allergy$709,501
R01 · FY2017 · AI · contact PI
c-Ski and the regulation of CD4 T cell-mediated autoimmunity and tolerance$427,500
R01 · FY2017 · AI · contact PI
A FOXP3 complex that controls human regulatory T cell function$424,500
R01 · FY2017 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$411,043
U19 · FY2017 · AI · contact PI
Molecular mechanisms of Th17 plasticity in MS$382,156
R01 · FY2017 · NS · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$362,503
R01 · FY2017 · CA · contact PI
Generating tolerance to antibody-based drugs$255,000
R21 · FY2017 · AI · contact PI
Core E: Immunology and Inflammation Core$192,402
P30 · FY2017 · DK · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$119,849
R01 · FY2017 · CA · contact PI
Core A: Administrative Core$44,434
U19 · FY2017 · AI · contact PI
Epithelial control of responses to allergen challenge and viral exacerbation$1,678,318
U19 · FY2016 · AI · contact PI
IL-33 and food allergy$566,296
R01 · FY2016 · AI · contact PI
TSLP and the Pathophysiology of Asthma$459,776
R01 · FY2016 · AI · contact PI
c-Ski and the regulation of CD4 T cell-mediated autoimmunity and tolerance$427,500
R01 · FY2016 · AI · contact PI
A FOXP3 complex that controls human regulatory T cell function$424,500
R01 · FY2016 · AI · contact PI
Epithelial regulation of ECM and leukocyte adhesion in viral-triggered asthma$406,303
U19 · FY2016 · AI · contact PI
Molecular mechanisms of Th17 plasticity in MS$382,156
R01 · FY2016 · NS · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$362,503
R01 · FY2016 · CA · contact PI
Core E: Immunology and Inflammation Core$192,401
P30 · FY2016 · DK · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$119,849
R01 · FY2016 · CA · contact PI
Core A: Administrative Core$32,856
U19 · FY2016 · AI · contact PI
Regulation of TSLP receptor expression and function in eczema in mice and man$543,059
R01 · FY2015 · AR
TSLP and the Pathophysiology of Asthma$459,776
R01 · FY2015 · AI · contact PI
c-Ski and the regulation of CD4 T cell-mediated autoimmunity and tolerance$427,500
R01 · FY2015 · AI · contact PI
Molecular mechanisms of Th17 plasticity in MS$382,156
R01 · FY2015 · NS · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$362,503
R01 · FY2015 · CA · contact PI
A FOXP3 complex that controls human regulatory T cell function$271,901
R01 · FY2015 · AI · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$94,680
R01 · FY2015 · CA · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$2,236,282
P01 · FY2014 · HL · contact PI
Regulation of TSLP receptor expression and function in eczema in mice and man$532,197
R01 · FY2014 · AR
TSLP and the Pathophysiology of Asthma$470,144
R01 · FY2014 · AI · contact PI
A FOXP3 complex that controls human regulatory T cell function$437,000
R56 · FY2014 · AI · contact PI
c-Ski and the regulation of CD4 T cell-mediated autoimmunity and tolerance$427,500
R01 · FY2014 · AI · contact PI
Molecular mechanisms of Th17 plasticity in MS$378,336
R01 · FY2014 · NS · contact PI
Control of tumor growth and metastasis by the cytokine TSLP$362,503
R01 · FY2014 · CA · contact PI
Thymic Stromal Lymphopoietin (TSLP) and Lung Inflammation and Imm$348,056
P01 · FY2014 · HL · contact PI
Administrative Core$150,967
P01 · FY2014 · HL · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$2,193,311
P01 · FY2013 · HL · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$992,339
P01 · FY2013 · HL · contact PI
Regulation of TSLP receptor expression and function in eczema in mice and man$515,908
R01 · FY2013 · AR
TSLP and the Pathophysiology of Asthma$441,937
R01 · FY2013 · AI · contact PI
Molecular mechanisms of Th17 plasticity in MS$382,156
R01 · FY2013 · NS · contact PI
Regulation of TSLP-Mediated Skin Inflammation$371,761
R01 · FY2013 · AR · contact PI
Thymic Stromal Lymphopoietin (TSLP) and Lung Inflammation and Imm$338,612
P01 · FY2013 · HL · contact PI
Administrative Core$149,688
P01 · FY2013 · HL · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$2,322,840
P01 · FY2012 · HL · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$1,002,502
P01 · FY2012 · HL · contact PI
Regulation of TSLP receptor expression and function in eczema in mice and man$543,059
R01 · FY2012 · AR
TSLP and the Pathophysiology of Asthma$488,344
R01 · FY2012 · AI · contact PI
Regulation of TSLP-Mediated Skin Inflammation$391,327
R01 · FY2012 · AR · contact PI
TSLP and Contact Hypersensitivity$382,631
R01 · FY2012 · AR · contact PI
Thymic Stromal Lymphopoietin (TSLP) and Lung Inflammation and Imm$343,081
P01 · FY2012 · HL · contact PI
TSLP and Childhood Asthma$203,917
R21 · FY2012 · HL · contact PI
Administrative Core$116,515
P01 · FY2012 · HL · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$2,329,483
P01 · FY2011 · HL · contact PI
Regulation of TSLP receptor expression and function in eczema in mice and man$581,620
R01 · FY2011 · AR
Thymic Stromal Lymphopoietin (TSLP) and Lung Inflammation and Imm$475,241
P01 · FY2011 · HL · contact PI
Regulation of TSLP-Mediated Skin Inflammation$391,327
R01 · FY2011 · AR · contact PI
TSLP and Contact Hypersensitivity$382,631
R01 · FY2011 · AR · contact PI
TSLP and Childhood Asthma$264,401
R21 · FY2011 · HL · contact PI
Functional Biology of Intestinal Epithelial Cells in Food Allergy$254,678
R21 · FY2011 · AI
Administrative Core$106,298
P01 · FY2011 · HL · contact PI
Regulation of pulmonary inflammation by leukocytes and extracellular matrix$2,412,695
P01 · FY2010 · HL · contact PI
Thymic Stromal Lymphopoietin (TSLP) and Lung Inflammation and Imm$466,647
P01 · FY2010 · HL · contact PI
Control of regulatory T cell differentiation and function$457,500
R56 · FY2010 · AI · contact PI
TSLP and the Pathophysiology of Asthma$431,435
R01 · FY2010 · AI · contact PI
Regulation of TSLP-Mediated Skin Inflammation$407,633
R01 · FY2010 · AR · contact PI
TSLP and Contact Hypersensitivity$398,574
R01 · FY2010 · AR · contact PI
Functional Biology of Intestinal Epithelial Cells in Food Allergy$229,156
R21 · FY2010 · AI
TSLP receptor in the regulation of cell development$179,968
R01 · FY2010 · AI · contact PI
TSLP Signaling in Dendritic Cells - Aim 3$145,365
U19 · FY2010 · AI · contact PI
Administrative Core$104,375
P01 · FY2010 · HL · contact PI
Activation Pathways that Upregulate TSLP Expression; Analyses AP-1 Promoter Sites$15,305
U19 · FY2010 · AI · contact PI
TSLP and the Pathophysiology of Asthma$435,793
R01 · FY2009 · AI · contact PI
Regulation of TSLP-Mediated Skin Inflammation$411,750
R01 · FY2009 · AR · contact PI
TSLP and Contact Hypersensitivity$402,600
R01 · FY2009 · AR · contact PI
TSLP receptor in the regulation of cell development$298,299
R01 · FY2009 · AI · contact PI
The role of the cytokine TSLP in food allergy$228,750
R21 · FY2009 · AI · contact PI
TSLP Signaling in Dendritic Cells - Aim 3$142,565
U19 · FY2009 · AI · contact PI
Activation Pathways that Upregulate TSLP Expression; Analyses AP-1 Promoter Sites$14,999
U19 · FY2009 · AI · contact PI
TSLP and the Pathophysiology of Asthma$435,793
R01 · FY2008 · AI · contact PI
TSLP and Contact Hypersensitivity$402,600
R01 · FY2008 · AR · contact PI
TSLP receptor in the regulation of cell development$298,299
R01 · FY2008 · AI · contact PI
The role of the cytokine TSLP in food allergy$274,500
R21 · FY2008 · AI · contact PI
TSLP Signaling in Dendritic Cells - Aim 3$138,411
U19 · FY2008 · AI · contact PI
Activation Pathways that Upregulate TSLP Expression; Analyses AP-1 Promoter Sites$14,564
U19 · FY2008 · AI · contact PI
TSLP and the Pathophysiology of Asthma$444,233
R01 · FY2007 · AI · contact PI
TSLP receptor in the regulation of cell development$304,076
R01 · FY2007 · AI · contact PI
FoxP3 control of peripheral regulatory T cell generation$222,116
R21 · FY2007 · AI · contact PI
TSLP Signaling in Dendritic Cells - Aim 3$136,983
U19 · FY2007 · AI · contact PI
Activation Pathways that Upregulate TSLP Expression; Analyses AP-1 Promoter Sites$14,417
U19 · FY2007 · AI · contact PI
TSLP and the Pathophysiology of Asthma$457,500
R01 · FY2006 · AI · contact PI
FOXP3: functional analysis of the gene mutated in mice$369,118
R01 · FY2006 · AI · contact PI
TSLP receptor in the regulation of cell development$313,158
R01 · FY2006 · AI · contact PI
FoxP3 control of peripheral regulatory T cell generation$228,750
R21 · FY2006 · AI · contact PI
TSLP Signaling in Dendritic Cells - Aim 3$136,976
U19 · FY2006 · AI · contact PI
Activation Pathways that Upregulate TSLP Expression; Analyses AP-1 Promoter Sites$33,638
U19 · FY2006 · AI · contact PI
FOXP3: functional analysis of the gene mutated in mice$378,000
R01 · FY2005 · AI
TSLP receptor in the regulation of cell development$289,122
R01 · FY2005 · AI
The Role of FoxP3 in Regulatory T Cell Function$263,250
R21 · FY2005 · AI
Extopic FoxP3 Expression and Diabetogenic T Cells$175,500
R21 · FY2005 · DK
FOXP3: functional analysis of the gene mutated in mice$378,000
R01 · FY2004 · AI
FoxP3 in Regulatory T Cell Function$263,250
R21 · FY2004 · AI
IPEX and Scurfin/FoxP3: Dysregulation of T cells$263,250
R21 · FY2004 · AI
Ectopic FoxP3 Expression and Diabetogenic T Cells$175,500
R21 · FY2004 · DK
IL2 RECEPTOR SIGNALING IN T LYMPHOCYTES$396,169
R01 · FY2003 · GM
FOXP3: functional analysis of the gene mutated in mice$378,000
R01 · FY2003 · AI
FUNCTIONAL CHARACTERIZATION OF CD69$337,601
R01 · FY2003 · AI
IPEX and Scurfin/FoxP3: Dysregulation of T cells$263,250
R21 · FY2003 · AI
FOXP3: functional analysis of the gene mutated in mice$378,000
R01 · FY2002 · AI
FUNCTIONAL CHARACTERIZATION OF CD69$327,769
R01 · FY2002 · AI
TSLP RECEPTOR IN THE REGULATION OF B CELL DEVELOPMENT$278,448
R01 · FY2002 · AI
FACS VANTAGE/SE$409,200
S10 · FY2001 · RR
FUNCTIONAL CHARACTERIZATION OF CD69$318,221
R01 · FY2001 · AI
TSLP RECEPTOR IN THE REGULATION OF B CELL DEVELOPMENT$270,338
R01 · FY2001 · AI
TSLP RECEPTOR IN THE REGULATION OF B CELL DEVELOPMENT$262,465
R01 · FY2000 · AI
FUNCTIONAL CHARACTERIZATION OF CD69$246,126
R01 · FY2000 · AI
CD69 INDUCED TNF PRODUCTION IN RHEUMATOID SYNOVIUM$71,300
R03 · FY2000 · AR