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Binghui Shen
Beckman Research Institute/City Of Hope
$21,743,081
Attributed
$25,284,298
Total exposure
11
Grants
9
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $2.9M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$25,284,298 · 11
By mechanism
R01$20,550,365 · 5
T32$1,840,435 · 1
U01$1,797,046 · 1
R21$391,740 · 1
P30$316,008 · 1
R29$264,471 · 1
Top collaborators
- Jeremy Michael Stark5 shared
- Zijie Sun5 shared
- Timothy R O'Connor4 shared
- David A. Horne3 shared
Most similar at Beckman Research Institute/City Of Hope
Same institution · by research overlap
- Jeremy Michael Stark$9,638,544
- Marcin Kortylewski$7,220,327
- Li Zheng$3,298,435
- Hua E Yu$13,108,796
- Zijie Sun$18,720,797
Others in their field
Top investigators on “Cells”
- Lawrence Corey · Fred Hutchinson Cancer Center$536,344,731
- Barton F Haynes · Duke University$457,457,619
- David Heimbrook · Leidos Biomedical Research, Inc.$454,789,509
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$299,104,942
- Dennis R. Burton · Scripps Research Institute$278,781,854
- Mary M Horowitz · Medical College Of Wisconsin$237,383,608
Research focus
CellsNucleaseResponseMalignant NeoplasmsDna BiosynthesisDna DamagePathway InteractionsMolecularDna RepairMutationExcisionRepairedDefectCancer CellPhenotypeIn VitroLeadGenomic InstabilityMouse ModelCancer InitiationEnzymesFundingCancer TherapyCancer Etiology
Grant awards (86)
Identification of small molecule inhibitors to exonuclease 1 for breast cancer treatment$611,800
U01 · FY2025 · CA · contact PI
Okazaki fragment maturation: mutagenesis and cell survival$547,800
R01 · FY2025 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$445,000
R01 · FY2025 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$249,533
T32 · FY2025 · CA
DNA repair gene mutations and prostate cancer$662,863
R01 · FY2024 · CA · contact PI
Identification of small molecule inhibitors to exonuclease 1 for breast cancer treatment$609,851
U01 · FY2024 · CA · contact PI
Okazaki fragment maturation: mutagenesis and cell survival$520,411
R01 · FY2024 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$445,000
R01 · FY2024 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$316,742
R01 · FY2024 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$240,284
T32 · FY2024 · CA
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$126,581
R01 · FY2024 · CA · contact PI
DNA repair gene mutations and prostate cancer$683,795
R01 · FY2023 · CA · contact PI
Identification of small molecule inhibitors to exonuclease 1 for breast cancer treatment$575,395
U01 · FY2023 · CA · contact PI
Okazaki fragment maturation: mutagenesis and cell survival$547,800
R01 · FY2023 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$333,413
R01 · FY2023 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$234,585
T32 · FY2023 · CA
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$122,195
R01 · FY2023 · CA · contact PI
DNA repair gene mutations and prostate cancer$683,795
R01 · FY2022 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$326,744
R01 · FY2022 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$233,749
T32 · FY2022 · CA · contact PI
Molecular and Cellular Biology of Cancer$65,011
P30 · FY2022 · CA · contact PI
DNA repair gene mutations and prostate cancer$697,751
R01 · FY2021 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$369,788
R01 · FY2021 · CA · contact PI
Molecular and Cellular Biology of Cancer$65,011
P30 · FY2021 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$1
R01 · FY2021 · CA · contact PI
DNA repair gene mutations and prostate cancer$716,750
R01 · FY2020 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$369,788
R01 · FY2020 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$333,413
R01 · FY2020 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$200,670
T32 · FY2020 · CA · contact PI
Molecular and Cellular Biology of Cancer$72,153
P30 · FY2020 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$358,693
R01 · FY2019 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$351,663
R01 · FY2019 · CA · contact PI
Molecular Mechanisms of BRCA1-Dependent DNA Damage Response and Tumorogenesis$340,437
R01 · FY2019 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$123,474
T32 · FY2019 · CA · contact PI
Molecular and Cellular Biology of Cancer$63,239
P30 · FY2019 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$369,788
R01 · FY2018 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$294,000
R01 · FY2018 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$181,497
T32 · FY2018 · CA · contact PI
Molecular and Cellular Biology of Cancer$48,511
P30 · FY2018 · CA · contact PI
Molecular and Cellular Biology of Cancer$2,083
P30 · FY2018 · CA · contact PI
FEN1-mediated Okazaki fragment maturation and its deficiency in cancer$369,788
R01 · FY2017 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$294,000
R01 · FY2017 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$191,581
T32 · FY2017 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$325,031
R01 · FY2016 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$294,000
R01 · FY2016 · CA · contact PI
DNA Damage Response and Oncogenic Signaling$185,062
T32 · FY2016 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$325,031
R01 · FY2015 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$294,000
R01 · FY2015 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$315,280
R01 · FY2014 · CA · contact PI
Dynamic functions of DNA2 counteract DNA replication stresses and tumorigenesis$294,000
R01 · FY2014 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$305,529
R01 · FY2013 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$243,165
R01 · FY2013 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$325,031
R01 · FY2012 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$258,686
R01 · FY2012 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$321,162
R01 · FY2011 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$258,686
R01 · FY2011 · CA · contact PI
Lung and other cancer etiological model of BER gene polymorphisms$175,110
R21 · FY2011 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$331,095
R01 · FY2010 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$266,687
R01 · FY2010 · CA · contact PI
Lung and other cancer etiological model of BER gene polymorphisms$216,630
R21 · FY2010 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$505,473
R01 · FY2009 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$331,095
R01 · FY2009 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$266,687
R01 · FY2009 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$331,760
R01 · FY2008 · CA · contact PI
Functional Analysis of FEN-1 Nuclease in Genome Stability and Cancers$333,755
R01 · FY2007 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$268,279
R01 · FY2007 · CA · contact PI
Function Analysis of FEN-1 Nuclease in Genome Stability$293,316
R01 · FY2006 · CA · contact PI
Role of Nucleases in RNA Primer Removal and Mutagenesis$276,290
R01 · FY2006 · CA · contact PI
Function Analysis of FEN-1 Nuclease in Genome Stability$300,375
R01 · FY2005 · CA
Role of Nucleases in RNA Primer Removal and Mutagenesis$282,940
R01 · FY2005 · CA
Function Analysis of FEN-1 Nuclease in Genome Stability$300,375
R01 · FY2004 · CA
Role of Nucleases in RNA Primer Removal and Mutagenesis$282,940
R01 · FY2004 · CA
Function Analysis of FEN-1 Nuclease in Genome Stability$300,375
R01 · FY2003 · CA
Role of Nucleases in RNA Primer Removal and Mutagenesis$284,174
R01 · FY2003 · CA
Role of Nucleases in RNA Primer Removal and Mutagenesis$69,000
R01 · FY2003 · CA
Function Analysis of FEN-1 Nuclease in Genome Stability$266,333
R01 · FY2002 · CA
NUCLEASES IN RNA PRIMER REMOVAL AND MUTAGENESIS$190,137
R01 · FY2002 · CA
NUCLEASES IN RNA PRIMER REMOVAL AND MUTAGENESIS$69,000
R01 · FY2002 · CA
NUCLEASES IN RNA PRIMER REMOVAL AND MUTAGENESIS$206,000
R01 · FY2001 · CA
NUCLEASES IN RNA PRIMER REMOVAL AND MUTAGENESIS$184,599
R01 · FY2001 · CA
STRUCTURE/FUNCTION OF A DNA REPAIR ENDONUCLEASE$133,984
R29 · FY2001 · CA
MECHANISTIC ANALYSIS OF SITE DIRECTED MUTANT NUCLEASE ENZYMES$121,168
P41 · FY2001 · RR
NUCLEASES IN RNA PRIMER REMOVAL AND MUTAGENESIS$63,692
R01 · FY2001 · CA
NUCLEASES IN RNA PRIMER REMOVAL AND MUTAGENESIS$358,388
R01 · FY2000 · CA
STRUCTURE/FUNCTION OF A DNA REPAIR ENDONUCLEASE$130,487
R29 · FY2000 · CA
MECHANISTIC ANALYSIS OF SITE DIRECTED MUTANT NUCLEASE ENZYMES$3,065
P41 · FY2000 · RR