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Zhenkun Lou

Mayo Clinic Rochester

$18,569,951
Attributed
$21,182,270
Total exposure
14
Grants
12
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.9M · FY200825
$2M$1.5M$1M$500K$0
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$21,182,270 · 14

By mechanism

R01$21,182,270 · 14

Top collaborators

Most similar at Mayo Clinic Rochester

Same institution · by research overlap

Others in their field

Top investigators on “Malignant Neoplasms

Research focus

Malignant NeoplasmsResponsePathway InteractionsRegulationCellsDna DamageTumorigenesisProteinsCancer TherapyAffectTumorMutationInsightBaseLinkDesignDna RepairBrca1 GeneCancer CellGenome StabilityPhosphorylationOverexpressionMalignant Breast NeoplasmKnockout Mice

Grant awards (60)

Ovcoming PARP Inhibitor Resistance$633,705
R01 · FY2025 · CA · contact PI
Mechanism and therapeutic targeting of castration resistance in SPOP-mutated prostate cancer$492,046
R01 · FY2025 · CA · contact PI
ATR: targeting mechanical stress induced EMT and immune suppression in triple negative breast cancer$369,203
R01 · FY2025 · CA
Sensitizing Ovarian Cancer To PARP inhibitor and platinum treatment$363,713
R01 · FY2025 · CA · contact PI
Mechanism and therapeutic targeting of castration resistance in SPOP-mutated prostate cancer$507,395
R01 · FY2024 · CA · contact PI
ATR: targeting mechanical stress induced EMT and immune suppression in triple negative breast cancer$350,743
R01 · FY2024 · CA
Sensitizing Ovarian Cancer To PARP inhibitor and platinum treatment$345,528
R01 · FY2024 · CA · contact PI
The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response$345,528
R01 · FY2024 · CA
ATR: targeting mechanical stress induced EMT and immune suppression in triple negative breast cancer$369,203
R01 · FY2023 · CA
Regulation of Necroptosis and inflammation$356,438
R01 · FY2023 · CA · contact PI
Sensitizing Ovarian Cancer To PARP inhibitor and platinum treatment$356,438
R01 · FY2023 · CA · contact PI
The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response$356,438
R01 · FY2023 · CA
Regulation of Necroptosis and inflammation$356,438
R01 · FY2022 · CA · contact PI
Sensitizing Ovarian Cancer To PARP inhibitor and platinum treatment$356,438
R01 · FY2022 · CA · contact PI
The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response$356,438
R01 · FY2022 · CA
UFM1 signaling in DNA damage response and cancer therapy$356,438
R01 · FY2022 · CA · contact PI
Sensitizing Ovarian Cancer To PARP inhibitor and platinum treatment$363,713
R01 · FY2021 · CA · contact PI
The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response$363,713
R01 · FY2021 · CA
Regulation of Necroptosis and inflammation$363,713
R01 · FY2021 · CA · contact PI
UFM1 signaling in DNA damage response and cancer therapy$363,713
R01 · FY2021 · CA · contact PI
Deubiquitinases in regulation of BRCA1 pathway$363,713
R01 · FY2020 · CA · contact PI
The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response$363,713
R01 · FY2020 · CA
Regulation of homologous recombination and cancer cell response to chemoradiotherapy$363,713
R01 · FY2020 · CA · contact PI
Regulation of Necroptosis and inflammation$363,713
R01 · FY2020 · CA · contact PI
UFM1 signaling in DNA damage response and cancer therapy$363,713
R01 · FY2020 · CA · contact PI
Regulation of Necroptosis and inflammation$363,713
R01 · FY2019 · CA · contact PI
Deubiquitinases in regulation of BRCA1 pathway$352,801
R01 · FY2019 · CA · contact PI
UFM1 signaling in DNA damage response and cancer therapy$352,801
R01 · FY2019 · CA · contact PI
Regulation of homologous recombination and cancer cell response to chemoradiotherapy$352,801
R01 · FY2019 · CA · contact PI
UFM1 signaling in DNA damage response and cancer therapy$363,713
R01 · FY2018 · CA · contact PI
Regulation of homologous recombination and cancer cell response to chemoradiotherapy$363,713
R01 · FY2018 · CA · contact PI
Ubiquitination and the DNA Damage Response Pathway$357,750
R01 · FY2018 · CA · contact PI
The Role of WSB1 in Tumorigenesis$329,925
R01 · FY2018 · CA · contact PI
Regulation of homologous recombination and cancer cell response to chemoradiotherapy$363,713
R01 · FY2017 · CA · contact PI
Ubiquitination and the DNA Damage Response Pathway$357,750
R01 · FY2017 · CA · contact PI
The Role of WSB1 in Tumorigenesis$329,925
R01 · FY2017 · CA · contact PI
Regulation of homologous recombination and cancer cell response to chemoradiotherapy$363,713
R01 · FY2016 · CA · contact PI
Ubiquitination and the DNA Damage Response Pathway$357,750
R01 · FY2016 · CA · contact PI
The Role of WSB1 in Tumorigenesis$329,925
R01 · FY2016 · CA · contact PI
Ubiquitination and the DNA Damage Response Pathway$357,750
R01 · FY2015 · CA · contact PI
The Role of WSB1 in Tumorigenesis$329,925
R01 · FY2015 · CA · contact PI
Regultion of p53 Deubiquitination$327,228
R01 · FY2015 · CA · contact PI
Ubiquitination and the DNA Damage Response Pathway$357,750
R01 · FY2014 · CA · contact PI
The Role of WSB1 in Tumorigenesis$329,925
R01 · FY2014 · CA · contact PI
Regultion of p53 Deubiquitination$317,411
R01 · FY2014 · CA · contact PI
Regultion of p53 Deubiquitination$307,594
R01 · FY2013 · CA · contact PI
Regulation of SirT1 by Deleted in Breast Cancer 1 (DBC1)$285,879
R01 · FY2013 · CA · contact PI
Regultion of p53 Deubiquitination$327,228
R01 · FY2012 · CA · contact PI
Regulation of SirT1 by Deleted in Breast Cancer 1 (DBC1)$304,127
R01 · FY2012 · CA · contact PI
The Role of MDC1 in Genome Maintenance and Tumor Suppression$304,127
R01 · FY2012 · CA · contact PI
Regultion of p53 Deubiquitination$327,228
R01 · FY2011 · CA · contact PI
The Role of MMSET in DNA damage response and Chemoradioresistance$317,411
R01 · FY2011 · CA · contact PI
Regulation of SirT1 by Deleted in Breast Cancer 1 (DBC1)$304,127
R01 · FY2011 · CA · contact PI
The Role of MDC1 in Genome Maintenance and Tumor Suppression$304,127
R01 · FY2011 · CA · contact PI
The Role of MMSET in DNA damage response and Chemoradioresistance$327,228
R01 · FY2010 · CA · contact PI
The Role of MDC1 in Genome Maintenance and Tumor Suppression$313,533
R01 · FY2010 · CA · contact PI
Regulation of SirT1 by Deleted in Breast Cancer 1 (DBC1)$313,533
R01 · FY2010 · CA · contact PI
The Role of MDC1 in Genome Maintenance and Tumor Suppression$313,533
R01 · FY2009 · CA · contact PI
Regulation of SirT1 by Deleted in Breast Cancer 1 (DBC1)$313,533
R01 · FY2009 · CA · contact PI
The Role of MDC1 in Genome Maintenance and Tumor Suppression$313,533
R01 · FY2008 · CA · contact PI