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Madesh Muniswamy

University Of Pennsylvania

$15,093,166
Attributed
$18,187,678
Total exposure
12
Grants
11
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.6M · FY200725
$2M$1.5M$1M$500K$0
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$18,187,678 · 12

By mechanism

R01$13,794,923 · 7
R35$2,432,469 · 1
S10$1,000,000 · 2
P01$539,536 · 1
R21$420,750 · 1

Most similar at University Of Pennsylvania

Same institution · by research overlap

Others in their field

Top investigators on “Cells

Research focus

CellsSignal TransductionMitochondriaMolecularUptakeFunctional DisorderMediatingComplexBioenergeticsBaseProteinsCell PhysiologyCell DeathLinkIn VivoHomeostasisPhysiologicalOxidation-ReductionRegulationEventIn VitroOxidative StressProductionFuture

Grant awards (55)

Characterize TMEM94 as ER Mg2+ uptake machinery and pathophysiological consequences.$586,516
R01 · FY2025 · HL · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$498,983
R35 · FY2025 · GM · contact PI
Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLD$472,438
R01 · FY2025 · DK · contact PI
Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLD$503,933
R01 · FY2024 · DK · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$498,983
R35 · FY2024 · GM · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$249,813
R35 · FY2024 · GM · contact PI
Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLD$557,993
R01 · FY2023 · DK · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$498,983
R35 · FY2023 · GM · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$250,000
R35 · FY2023 · GM · contact PI
Molecular mechanism of Ca2+-induced mitochondrial shape transition in metazoans$399,698
R01 · FY2022 · GM · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$224,320
R35 · FY2022 · GM · contact PI
Magnesium flux compendium: Discover ligands, channels, and metabolic signals$211,387
R35 · FY2022 · GM · contact PI
Molecular mechanism of Ca2+-induced mitochondrial shape transition in metazoans$24,646
R01 · FY2022 · GM · contact PI
Molecular mechanism of Ca2+-induced mitochondrial shape transition in metazoans$461,096
R01 · FY2021 · GM · contact PI
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for Atherosclerosis$445,140
R01 · FY2021 · HL
Essential Role for SPG7 in Mitochondrial Permeability Transition Pore Assembly and Function$307,245
R01 · FY2021 · GM · contact PI
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for Atherosclerosis$73,128
R01 · FY2021 · HL
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for Atherosclerosis$450,042
R01 · FY2020 · HL
Molecular mechanism of Ca2+-induced mitochondrial shape transition in metazoans$400,748
R01 · FY2020 · GM · contact PI
Essential Role for SPG7 in Mitochondrial Permeability Transition Pore Assembly and Function$305,295
R01 · FY2020 · GM · contact PI
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for Atherosclerosis$69,038
R01 · FY2020 · HL
Molecular mechanism of Ca2+-induced mitochondrial shape transition in metazoans$43,373
R01 · FY2020 · GM · contact PI
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for Atherosclerosis$469,772
R01 · FY2019 · HL
Molecular mechanism of Ca2+-induced mitochondrial shape transition in metazoans$420,364
R01 · FY2019 · GM · contact PI
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for Atherosclerosis$474,184
R01 · FY2018 · HL
Coordination of Pathophysiologic endothelial cell signaling by ROS$328,843
R01 · FY2018 · HL · contact PI
Coordination of Pathophysiologic endothelial cell signaling by ROS$120,922
R01 · FY2018 · HL · contact PI
Coordination of Pathophysiologic endothelial cell signaling by ROS$459,342
R01 · FY2017 · HL · contact PI
Inhibition of MCUR1-MCU mediated mitochondrial Ca2+ uptake prevents I/R injury$390,000
R01 · FY2017 · HL · contact PI
Spectral revelations of mitochondrial Ca2+ flux interactome$333,540
R01 · FY2017 · GM · contact PI
Coordination of Pathophysiologic endothelial cell signaling by ROS$468,640
R01 · FY2016 · HL · contact PI
Spectral revelations of mitochondrial Ca2+ flux interactome$396,392
R01 · FY2016 · GM · contact PI
Inhibition of MCUR1-MCU mediated mitochondrial Ca2+ uptake prevents I/R injury$390,000
R01 · FY2016 · HL · contact PI
Coordination of Pathophysiologic endothelial cell signaling by ROS$470,504
R01 · FY2015 · HL · contact PI
Inhibition of MCUR1-MCU mediated mitochondrial Ca2+ uptake prevents I/R injury$384,150
R01 · FY2015 · HL · contact PI
Spectral revelations of mitochondrial Ca2+ flux interactome$333,540
R01 · FY2015 · GM · contact PI
Spectral revelations of mitochondrial Ca2+ flux interactome$76,852
R01 · FY2015 · GM · contact PI
Coordination of Pathophysiologic endothelial cell signaling by ROS$485,392
R01 · FY2014 · HL · contact PI
Inhibition of MCUR1-MCU mediated mitochondrial Ca2+ uptake prevents I/R injury$389,375
R01 · FY2014 · HL · contact PI
Spectral revelations of mitochondrial Ca2+ flux interactome$361,413
R01 · FY2014 · GM · contact PI
Coordination of Pathophysiologic Endothelial Cell Signaling by ROS$334,125
R01 · FY2012 · HL · contact PI
ROS-dependent STIM1 activation and Ca2+ entry in lung inflammation$191,250
R21 · FY2012 · HL · contact PI
Coordination of Pathophysiologic Endothelial Cell Signaling by ROS$337,500
R01 · FY2011 · HL · contact PI
ROS-dependent STIM1 activation and Ca2+ entry in lung inflammation$229,500
R21 · FY2011 · HL · contact PI
CORE--Pulmonary Imaging and Morphology$105,302
P01 · FY2011 · HL · contact PI
Multiphoton Confocal Microscopy for Biomedical Research$500,000
S10 · FY2010 · RR · contact PI
Coordination of Pathophysiologic Endothelial Cell Signaling by ROS$337,500
R01 · FY2010 · HL · contact PI
CORE--Pulmonary Imaging and Morphology$105,302
P01 · FY2010 · HL · contact PI
Coordination of Pathophysiologic Endothelial Cell Signaling by ROS$337,500
R01 · FY2009 · HL · contact PI
Coordination of Pathophysiologic Endothelial Cell Signaling by ROS$272,244
R01 · FY2009 · HL · contact PI
CORE--Pulmonary Imaging and Morphology$109,644
P01 · FY2009 · HL · contact PI
Coordination of Pathophysiologic Endothelial Cell Signaling by ROS$322,500
R01 · FY2008 · HL · contact PI
CORE--Pulmonary Imaging and Morphology$109,644
P01 · FY2008 · HL · contact PI
Multiphoton upgrade of confocal microscope for live organ and tissue imaging$500,000
S10 · FY2007 · RR · contact PI
CORE--Pulmonary Imaging and Morphology$109,644
P01 · FY2007 · HL · contact PI