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Frederick J Sigworth

Yale University

$18,865,195
Attributed
$18,865,195
Total exposure
14
Grants
7
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $2.1M · FY200524
$2.5M$1.9M$1.3M$625K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24

Funding mix

By agency

NIH$18,865,195 · 14

By mechanism

R01$12,440,673 · 3
S10$2,450,000 · 2
P01$1,241,598 · 3
T32$990,770 · 2
R42$783,321 · 1
R21$452,468 · 1

Top collaborators

No co-investigators on record.

Most similar at Yale University

Same institution · by research overlap

Others in their field

Top investigators on “Ion Channel

Research focus

Ion ChannelParticleStructurePotassium ChannelProteinsMembrane PotentialsVoltageResolutionCryoelectron MicroscopyImageReconstructionReconstitutionVesicleLipidsInterestVoltage /Patch ClampDensityRestSensorMembrane ProteinsImage ProcessingMapsMolecular ConformationProtein Structure

Grant awards (55)

Fluctuations in Ionic Current through Membrane Channels$470,292
R01 · FY2024 · NS · contact PI
Fluctuations in Ionic Current through Membrane Channels$484,835
R01 · FY2023 · NS · contact PI
Fluctuations in Ionic Current through Membrane Channels$536,859
R01 · FY2022 · NS · contact PI
Fluctuations in Ionic Current through Membrane Channels$536,859
R01 · FY2021 · NS · contact PI
Fluctuations in Ionic Current through Membrane Channels$553,679
R01 · FY2020 · NS · contact PI
Curriculum: principles of cryo-EM structure determination$124,200
R25 · FY2020 · EY · contact PI
Curriculum: principles of cryo-EM structure determination$124,200
R25 · FY2019 · EY · contact PI
High-throughput electron cryo-microscope$1,950,000
S10 · FY2018 · OD · contact PI
Curriculum: principles of cryo-EM structure determination$123,720
R25 · FY2018 · EY · contact PI
Fluctuations in Ionic Current Through Membrane Channels$396,493
R01 · FY2017 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$396,493
R01 · FY2016 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$396,493
R01 · FY2015 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$402,268
R01 · FY2014 · NS · contact PI
Cryo-EM structure of a membrane-embedded glutamate receptor$206,043
R21 · FY2014 · NS · contact PI
Cryo-EM structure of a membrane-embedded glutamate receptor$246,425
R21 · FY2013 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$416,432
R01 · FY2012 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$407,971
R01 · FY2011 · NS · contact PI
Single particle reconstruction$244,294
P01 · FY2011 · GM · contact PI
Fluctuations in Ionic Current Through Membrane Channels$423,918
R01 · FY2010 · NS · contact PI
Patch Clamp Amplifiers on a Chip$325,680
R42 · FY2010 · NS · contact PI
Single particle reconstruction$244,879
P01 · FY2010 · GM · contact PI
Patch Clamp Amplifiers on a Chip$94,865
R42 · FY2010 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$80,458
R01 · FY2010 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$420,291
R01 · FY2009 · NS · contact PI
Patch Clamp Amplifiers on a Chip$362,776
R42 · FY2009 · NS · contact PI
Single particle reconstruction$238,497
P01 · FY2009 · GM · contact PI
Fluctuations in Ionic Current Through Membrane Channels$577,064
R01 · FY2008 · NS · contact PI
Single particle reconstruction$239,929
P01 · FY2008 · GM · contact PI
Fluctuations in Ionic Current Through Membrane Channels$583,473
R01 · FY2007 · NS · contact PI
Single particle reconstruction$273,999
P01 · FY2007 · GM · contact PI
Patch Clamp Amplifiers on a Chip$134,245
R41 · FY2007 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$583,397
R01 · FY2006 · NS · contact PI
Fluctuations in Ionic Current Through Membrane Channels$584,678
R01 · FY2005 · NS
New Technologies for Patch-Clamp Recording$277,235
R01 · FY2005 · EB
FLUCTUATIONS IN IONIC CURRENT THROUGH MEMBRANE CHANNELS$545,971
R01 · FY2004 · NS
New Technologies for Patch-Clamp Recording$277,553
R01 · FY2004 · EB
FLUCTUATIONS IN IONIC CURRENT THROUGH MEMBRANE CHANNELS$530,115
R01 · FY2003 · NS
New Technologies for Patch-Clamp Recording$277,870
R01 · FY2003 · EB
TRAINING PROGRAM IN MOLECULAR NEUROPHYSIOLOGY$216,795
T32 · FY2003 · NS
FLUCTUATIONS IN IONIC CURRENT THROUGH MEMBRANE CHANNELS$40,000
R01 · FY2003 · NS
FLUCTUATIONS IN IONIC CURRENT THROUGH MEMBRANE CHANNELS$514,713
R01 · FY2002 · NS
New Technologies for Patch-Clamp Recording$278,188
R01 · FY2002 · RR
TRAINING PROGRAM IN MOLECULAR NEUROPHYSIOLOGY$171,949
T32 · FY2002 · NS
CORE--INSTRUMENTATION$0
P01 · FY2002 · NS
FUNCTION/STRUCTURE OF BK CHANNELS$0
P01 · FY2002 · NS
FLUCTUATIONS IN IONIC CURRENT THROUGH MEMBRANE CHANNELS$499,751
R01 · FY2001 · NS
New Technologies for Patch-Clamp Recording$300,330
R01 · FY2001 · RR
TRAINING PROGRAM IN MOLECULAR NEUROPHYSIOLOGY$169,391
T32 · FY2001 · NS
CORE--INSTRUMENTATION$0
P01 · FY2001 · NS
FUNCTION/STRUCTURE OF BK CHANNELS$0
P01 · FY2001 · NS
FLUCTUATIONS IN IONIC CURRENT THROUGH MEMBRANE CHANNELS$551,265
R01 · FY2000 · NS
FIELD-EMISSION ELECTRON MICROSCOPE FOR MACROMOLECULES$500,000
S10 · FY2000 · RR
CELLULAR &MOLECULAR PHYSIOLOGY OF ORGAN FUNCTION$267,870
T32 · FY2000 · GM
TRAINING PROGRAM IN MOLECULAR NEUROPHYSIOLOGY$164,765
T32 · FY2000 · NS
NEW TECHNOLOGIES FOR PATCH CLAMP RECORDING$95,729
R01 · FY2000 · RR