← Leaderboards
John E Sondek
Univ Of North Carolina Chapel Hill
$15,232,788
Attributed
$20,647,680
Total exposure
16
Grants
11
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $1.9M · FY2005–25$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$20,647,680 · 16
By mechanism
R01$15,699,311 · 7
R56$1,511,798 · 1
P30$1,435,823 · 3
R35$1,283,052 · 1
S10$437,000 · 1
R41$276,339 · 1
Top collaborators
- Qisheng Zhang9 shared
- T Kendall Harden7 shared
- Kenneth Hugh Pearce6 shared
- Rihe Liu4 shared
- Li-An Yeh2 shared
- John Scott1 shared
Most similar at Univ Of North Carolina Chapel Hill
Same institution · by research overlap
- Qisheng Zhang$4,632,517
- Kenneth Hugh Pearce$13,826,383
- Sharon L Campbell$16,019,656
Others in their field
Top investigators on “Structure”
- David Heimbrook · Leidos Biomedical Research, Inc.$475,333,582
- Barton F Haynes · Duke University$444,977,767
- Lawrence Corey · Fred Hutchinson Cancer Center$334,646,086
- Gary D Acton · University Of California-Davis$320,373,312
- Mitchell J Malone · Texas A&M Research Foundation$320,373,312
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$315,257,203
Research focus
StructureSignal TransductionProteinsRegulationBaseBiochemicalPhosphatidylinositolsMalignant NeoplasmsMolecularMembranePhospholipase CResponseComplexResolutionIsoenzymesBiologicalDesignBiological ProcessCell PhysiologyCellsMediatingDrug DevelopmentProtein PurificationMolecular Dynamics
Grant awards (71)
Phospholipase C Isozymes$427,684
R35 · FY2025 · GM · contact PI
Structural Biology$182,751
P30 · FY2025 · CA · contact PI
Discovery of allosteric activators of phospholipase C-gamma2 to treat Alzheimer's disease$748,573
R56 · FY2024 · AG
A high-throughput platform to identify selective allosteric inhibitors of the PLC-y isozymes$508,118
R01 · FY2024 · CA
Phospholipase C Isozymes$427,684
R35 · FY2024 · GM · contact PI
Structural Biology$160,222
P30 · FY2024 · CA · contact PI
Discovery of allosteric activators of phospholipase C-gamma2 to treat Alzheimer's disease$763,225
R56 · FY2023 · AG
A high-throughput platform to identify selective allosteric inhibitors of the PLC-y isozymes$536,812
R01 · FY2023 · CA
Phospholipase C Isozymes$427,684
R35 · FY2023 · GM · contact PI
Structural Biology$178,027
P30 · FY2023 · CA · contact PI
A high-throughput platform to identify selective allosteric inhibitors of the PLC-y isozymes$583,609
R01 · FY2022 · CA
Structural Biology$178,027
P30 · FY2022 · CA · contact PI
A high-throughput platform to identify selective allosteric inhibitors of the PLC-y isozymes$569,708
R01 · FY2021 · CA
Regulation of phospholipase C$425,572
R01 · FY2021 · GM · contact PI
Structural Biology$178,027
P30 · FY2021 · CA · contact PI
Regulation of phospholipase C$425,572
R01 · FY2020 · GM · contact PI
Structural Biology$111,870
P30 · FY2020 · CA · contact PI
Regulation of phospholipase C$403,371
R01 · FY2019 · GM · contact PI
Inhibition of GTPases and G proteins to treat human disease$358,307
R01 · FY2019 · GM · contact PI
Structural Biology$108,436
P30 · FY2019 · CA · contact PI
Regulation of phospholipase C$68,768
R01 · FY2019 · GM · contact PI
Regulation of phospholipase C$425,572
R01 · FY2018 · GM · contact PI
Inhibition of GTPases and G proteins to treat human disease$358,307
R01 · FY2018 · GM · contact PI
A cell-free, high-throughput screening service for accelerated GPCR ligand discovery$276,339
R41 · FY2018 · GM · contact PI
Structural Biology$111,872
P30 · FY2018 · CA · contact PI
Structural Biology$2,967
P30 · FY2018 · CA · contact PI
Structural Biology$2,103
P30 · FY2018 · CA · contact PI
Structural Biology$1,367
P30 · FY2018 · CA · contact PI
Inhibition of GTPases and G proteins to treat human disease$358,307
R01 · FY2017 · GM · contact PI
Structural Biology$109,750
P30 · FY2017 · CA · contact PI
Inhibition of GTPases and G proteins to treat human disease$358,307
R01 · FY2016 · GM · contact PI
Structural Biology$110,404
P30 · FY2016 · CA · contact PI
Regulation of Phospholipase C$407,000
R01 · FY2015 · GM · contact PI
Regulation of Phospholipase C$407,000
R01 · FY2014 · GM · contact PI
Small molecule inhibition of Rho GTPase activation to probe signaling cascades$290,948
R01 · FY2014 · CA · contact PI
Regulation of Phospholipase C$392,756
R01 · FY2013 · GM · contact PI
Small molecule inhibition of Rho GTPase activation to probe signaling cascades$281,949
R01 · FY2013 · CA · contact PI
High-throughput screens to identify modulators of phospholipase C isozymes$271,358
R01 · FY2013 · GM
Regulation of Phospholipase C$407,000
R01 · FY2012 · GM · contact PI
Small molecule inhibition of Rho GTPase activation to probe signaling cascades$312,946
R01 · FY2012 · CA · contact PI
High-throughput screens to identify modulators of phospholipase C isozymes$281,200
R01 · FY2012 · GM
Regulation of phospholipase C$385,053
R01 · FY2011 · GM · contact PI
Functions and regulation of Dbl-family guanine nucleotide exchange factors$289,264
R01 · FY2011 · GM · contact PI
High-throughput screens to identify modulators of phospholipase C isozymes$281,200
R01 · FY2011 · GM
Regulation of phospholipase C$389,017
R01 · FY2010 · GM · contact PI
Functions and regulation of Dbl-family guanine nucleotide exchange factors$292,210
R01 · FY2010 · GM · contact PI
GBeta5/RGS proteins and GPCR signaling$274,626
R01 · FY2010 · GM · contact PI
Regulation of phospholipase C$381,044
R01 · FY2009 · GM · contact PI
Functions and regulation of Dbl-family guanine nucleotide exchange factors$294,939
R01 · FY2009 · GM · contact PI
GBeta5/RGS proteins and GPCR signaling$277,400
R01 · FY2009 · GM · contact PI
Functions and regulation of Dbl-family guanine nucleotide exchange factors$74,990
R01 · FY2009 · GM · contact PI
Regulation of phospholipase C$368,358
R01 · FY2008 · GM · contact PI
Functions and regulation of Dbl-family guanine nucleotide exchange factors$293,475
R01 · FY2008 · GM · contact PI
GBeta5/RGS proteins and GPCR signaling$277,400
R01 · FY2008 · GM · contact PI
Acquisition of a State of the Art Crystallographic Cluster$437,000
S10 · FY2007 · RR · contact PI
Regulation of Phospholipase C$350,568
R01 · FY2007 · GM · contact PI
GBeta5/RGS proteins and GPCR signaling$277,400
R01 · FY2007 · GM · contact PI
Regulation of Phospholipase C$120,000
R01 · FY2007 · GM · contact PI
Regulation of Phospholipase C$350,605
R01 · FY2006 · GM · contact PI
Regulation of Phospholipase C$348,670
R01 · FY2005 · GM
Tiam1, a prototypical Rho-family GEF$84,427
R01 · FY2005 · GM
REGULATOR OF G PROTEIN SIGNALING (RGS) 9-1, G PROTEIN BETA 5 SUBUNIT AND RGS9$4,357
P41 · FY2005 · RR
Regulation of Phospholipase C$349,100
R01 · FY2004 · GM
Tiam1, a prototypical Rho-family GEF$251,996
R01 · FY2004 · GM
Tiam1, a prototypical Rho-family GEF$251,996
R01 · FY2003 · GM
Tiam1, a prototypical Rho-family GEF$251,996
R01 · FY2002 · GM
G PROTEIN COUPLED PLC B ISOZYMES$171,305
R01 · FY2002 · GM
Structures of Novel R7 and R12 RGS Protein Domains$0
P01 · FY2002 · GM
Tiam1, a prototypical Rho-family GEF$251,996
R01 · FY2001 · GM
G PROTEIN COUPLED PLC B ISOZYMES$166,317
R01 · FY2001 · GM
G PROTEIN COUPLED PLC B ISOZYMES$161,472
R01 · FY2000 · GM