← Leaderboards
Matthew J Lazzara
Massachusetts Institute Of Technology
$5,608,363
Attributed
$6,875,408
Total exposure
7
Grants
6
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $4.1M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$15,777,322 · 8
By mechanism
U54$10,624,580 · 3
U01$2,493,479 · 1
R01$1,743,464 · 1
R21$790,626 · 2
F32$125,173 · 1
Top collaborators
- Kevin A Janes7 shared
- Damien Thevenin6 shared
- Shayn Peirce-Cottler2 shared
- Benjamin W. Purow1 shared
Most similar at Massachusetts Institute Of Technology
Same institution · by research overlap
- Peter C Dedon$29,387,499
- Leon Marcel Bellan$3,952,579
- Kerry A Emanuel$5,970,162
- Akshay Venkatesh$8,137,892
Others in their field
Top investigators on “Cells”
- Lawrence Corey · Fred Hutchinson Cancer Center$536,344,731
- Barton F Haynes · Duke University$457,457,619
- David Heimbrook · Leidos Biomedical Research, Inc.$454,789,509
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$299,104,942
- Dennis R. Burton · Scripps Research Institute$278,781,854
- Mary M Horowitz · Medical College Of Wisconsin$237,383,608
Research focus
CellsSignal TransductionPhenotypeMalignant NeoplasmsSystems BiologyComplexResponseEpidermal Growth Factor ReceptorExperimental StudyEngineeringPhosphorylationPathway InteractionsOncogenicSystems AnalysisRegulationComputer ModelsMeasurementTumorDesignPredictive ModelingImageMutantMutationLead
Grant awards (31)
Systems Analysis of Stress-adapted Cancer Organelles (SASCO) Center$2,285,637
U54 · FY2025 · CA
EGFR signaling network adaptations to overcome RAS-induced membrane stress in glioblastoma$371,330
U54 · FY2025 · CA · contact PI
Multiscale Computational Modeling to Design Patterned Tissue Assembloids for Biomanufacturing$205,679
R21 · FY2025 · EB · contact PI
Systems Analysis of Stress-adapted Cancer Organelles (SASCO) Center$2,018,318
U54 · FY2024 · CA
EGFR signaling network adaptations to overcome RAS-induced membrane stress in glioblastoma$352,763
U54 · FY2024 · CA · contact PI
Multiscale Computational Modeling to Design Patterned Tissue Assembloids for Biomanufacturing$169,702
R21 · FY2024 · EB · contact PI
EGFR signaling network adaptations to overcome RAS-induced membrane stress in glioblastoma$90,920
U54 · FY2024 · CA · contact PI
Cytoskeletal dynamics during uncontrolled macropinocytosis-induced cancer cell death$90,920
U54 · FY2024 · CA
Systems Analysis of Stress-adapted Cancer Organelles (SASCO) Center$2,081,447
U54 · FY2023 · CA
Optimal control models of epithelial-mesenchymal transition for the design of pancreas cancer combination therapy$452,330
U01 · FY2023 · CA · contact PI
Promoting Receptor Protein Tyrosine Phosphatase Activity by Targeting Transmembrane Domain Interactions$395,072
R01 · FY2023 · GM
EGFR signaling network adaptations to overcome RAS-induced membrane stress in glioblastoma$364,251
U54 · FY2023 · CA · contact PI
Metabolic changes accompanying durable, hypoxia-driven EMT in pancreas cancer$167,870
U01 · FY2023 · CA · contact PI
EGFR signaling network adaptations to overcome RAS-induced membrane stress in glioblastoma$166,977
U54 · FY2023 · CA · contact PI
A synthetic systems biology approach to predict context-specific mechanisms for SHP2 functional activity and resistance to SHP2 inhibition$166,977
U54 · FY2023 · CA
Open phase-separation models for cancer systems biology$166,402
U54 · FY2023 · CA
Promoting Receptor Protein Tyrosine Phosphatase Activity by Targeting Transmembrane Domain Interactions$90,505
R01 · FY2023 · GM
Systems Analysis of Stress-adapted Cancer Organelles (SASCO) Center$2,092,213
U54 · FY2022 · CA
Optimal control models of epithelial-mesenchymal transition for the design of pancreas cancer combination therapy$452,330
U01 · FY2022 · CA · contact PI
Promoting Receptor Protein Tyrosine Phosphatase Activity by Targeting Transmembrane Domain Interactions$396,263
R01 · FY2022 · GM
EGFR signaling network adaptations to overcome RAS-induced membrane stress in glioblastoma$376,425
U54 · FY2022 · CA · contact PI
Promoting Receptor Protein Tyrosine Phosphatase Activity by TargetingTransmembrane Domain Interactions$63,570
R01 · FY2022 · GM
Optimal control models of epithelial-mesenchymal transition for the design of pancreas cancer combination therapy$461,562
U01 · FY2021 · CA · contact PI
Promoting Receptor Protein Tyrosine Phosphatase Activity by Targeting Transmembrane Domain Interactions$397,420
R01 · FY2021 · GM
Optimal control models of epithelial-mesenchymal transition for the design of pancreas cancer combination therapy$461,276
U01 · FY2020 · CA · contact PI
Engineering ERK-specificity for cancer suicide gene therapy$415,245
R21 · FY2020 · CA · contact PI
Promoting Receptor Protein Tyrosine Phosphatase Activity by Targeting Transmembrane Domain Interactions$400,634
R01 · FY2020 · GM
Optimal control models of epithelial-mesenchymal transition for the design of pancreas cancer combination therapy$498,111
U01 · FY2019 · CA · contact PI
Quantitative Analysis of ErbB-Targeted-Drug Efficacy$26,449
F32 · FY2007 · CA · contact PI
Quantitative Analysis of ErbB-Targeted-Drug Efficacy$50,428
F32 · FY2006 · CA · contact PI
Quantitative Analysis of ErbB-Targeted-Drug Efficacy$48,296
F32 · FY2005 · CA