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Ophir D Klein

University Of California, San Francisco

$31,591,158
Attributed
$54,955,493
Total exposure
27
Grants
22
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $6.9M · FY200725
$10M$7.5M$5M$2.5M$0
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$54,955,493 · 27

By mechanism

R01$13,154,216 · 8
U24$11,961,481 · 1
U01$8,751,100 · 2
R35$8,036,982 · 1
RC2$4,000,000 · 1
DP2$2,317,500 · 1

Top collaborators

Others in their field

Top investigators on “Tissues

Research focus

TissuesMolecularCellsGeneticBaseGenesSignal TransductionRegulationFutureStem CellsEpithelialPathway InteractionsEpitheliumInterestTooth StructureRepairedLearningSignal PathwayOrganShapesCraniofacialRegenerativeIncisorDental Caries

Grant awards (96)

Consortium on Intestinal Regeneration and Fetal Reversion: from Atlas to Therapy$2,000,000
RC2 · FY2025 · DK · contact PI
A Team Science Approach to the Co Development of Oral Mucosa for Therapeutic Purposes$1,240,877
RM1 · FY2025 · DE · contact PI
Mechanisms of hyperactive Ras signaling in craniofacial and dental diseases$600,029
R01 · FY2025 · DE · contact PI
How Patterned Mesenchymal-Epithelial interactions Shape Intestinal Crypts$537,265
R01 · FY2025 · DK · contact PI
Developmental and molecular basis for a craniofacial metabolic syndrome$252,752
R21 · FY2025 · DE
Consortium on Intestinal Regeneration and Fetal Reversion: from Atlas to Therapy$2,000,000
RC2 · FY2024 · DK · contact PI
How Patterned Mesenchymal-Epithelial interactions Shape Intestinal Crypts$573,083
R01 · FY2024 · DK · contact PI
The physical and molecular mechanisms of intestinal villus morphogenesis and repair$546,769
R01 · FY2024 · DK
2024 Epithelial Stem Cells and Niches Gordon Research Conference and Seminar$41,520
R13 · FY2024 · AR · contact PI
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,030,250
R35 · FY2023 · DE · contact PI
Enamel atlas: systems-level amelogenesis tools at multiple scales$641,243
UH3 · FY2023 · DE · contact PI
How Patterned Mesenchymal-Epithelial interactions Shape Intestinal Crypts$596,962
R01 · FY2023 · DK · contact PI
The physical and molecular mechanisms of intestinal villus morphogenesis and repair$569,551
R01 · FY2023 · DK
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$403,750
U01 · FY2023 · DK · contact PI
Cellular and molecular control of tooth morphogenesis$383,563
R01 · FY2023 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$320,000
U01 · FY2023 · DK · contact PI
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,019,948
R35 · FY2022 · DE · contact PI
Enamel atlas: systems-level amelogenesis tools at multiple scales$636,476
UH3 · FY2022 · DE · contact PI
How Patterned Mesenchymal-Epithelial interactions Shape Intestinal Crypts$596,962
R01 · FY2022 · DK · contact PI
The physical and molecular mechanisms of intestinal villus morphogenesis and repair$569,551
R01 · FY2022 · DK
Regulation of organogenesis through regional variations in tissue mechanics$462,377
R01 · FY2022 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$403,750
U01 · FY2022 · DK · contact PI
Cellular and molecular control of tooth morphogenesis$379,727
R01 · FY2022 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$279,654
U01 · FY2022 · DK · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$70,874
U01 · FY2022 · DK · contact PI
Cellular and molecular control of tooth morphogenesis$30,742
R01 · FY2022 · DE · contact PI
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,030,250
R35 · FY2021 · DE · contact PI
Enamel atlas: systems-level amelogenesis tools at multiple scales$644,123
UH3 · FY2021 · DE · contact PI
The physical and molecular mechanisms of intestinal villus morphogenesis and repair$570,475
R01 · FY2021 · DK
Cellular and molecular control of tooth morphogenesis$497,985
R01 · FY2021 · DE · contact PI
Regulation of organogenesis through regional variations in tissue mechanics$469,338
R01 · FY2021 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$403,750
U01 · FY2021 · DK · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$279,654
U01 · FY2021 · DK · contact PI
Using human intestinal organoids to model IBD pathogenesis$242,250
R21 · FY2021 · DK · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$65,412
U01 · FY2021 · DK · contact PI
Cellular and molecular control of tooth morphogenesis$39,040
R01 · FY2021 · DE · contact PI
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,131,017
R35 · FY2020 · DE · contact PI
The physical and molecular mechanisms of intestinal villus morphogenesis and repair$584,002
R01 · FY2020 · DK
Enamel atlas: systems-level amelogenesis tools at multiple scales$546,441
UG3 · FY2020 · DE · contact PI
Regulation of organogenesis through regional variations in tissue mechanics$471,438
R01 · FY2020 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$403,750
U01 · FY2020 · DK · contact PI
Cellular and molecular control of tooth morphogenesis$382,969
R01 · FY2020 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$279,931
U01 · FY2020 · DK · contact PI
Using human intestinal organoids to model IBD pathogenesis$201,875
R21 · FY2020 · DK · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$87,216
U01 · FY2020 · DK · contact PI
Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)$3,970,932
U24 · FY2019 · DE
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,030,250
R35 · FY2019 · DE · contact PI
Enamel atlas: systems-level amelogenesis tools at multiple scales$573,472
UG3 · FY2019 · DE · contact PI
Regulation of organogenesis through regional variations in tissue mechanics$471,472
R01 · FY2019 · DE · contact PI
The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment$401,666
U01 · FY2019 · DK · contact PI
Cellular and molecular control of tooth morphogenesis$381,188
R01 · FY2019 · DE · contact PI
Harnessing natural stem cell-based strategies for mammalian dental renewal$100,767
R35 · FY2019 · DE · contact PI
Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)$3,978,064
U24 · FY2018 · DE
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,030,250
R35 · FY2018 · DE · contact PI
Developing 3D Craniofacial Morphometry Data and Tools to Transform Dysmorphology$641,023
U01 · FY2018 · DE
Regulation of organogenesis through regional variations in tissue mechanics$468,521
R01 · FY2018 · DE · contact PI
Regulation of distinct pools of intestinal stem cells$356,625
U01 · FY2018 · DK · contact PI
Regulation of distinct pools of intestinal stem cells$81,989
U01 · FY2018 · DK · contact PI
2018 Craniofacial Morphogenesis and Tissue Regeneration Gordon Research Conference and Gordon Research Seminar$23,000
R13 · FY2018 · DE · contact PI
Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)$4,012,485
U24 · FY2017 · DE
Harnessing natural stem cell-based strategies for mammalian dental renewal$1,030,250
R35 · FY2017 · DE · contact PI
Developing 3D Craniofacial Morphometry Data and Tools to Transform Dysmorphology$648,778
U01 · FY2017 · DE
Regulation of distinct pools of intestinal stem cells$356,625
U01 · FY2017 · DK · contact PI
Regulation of distinct pools of intestinal stem cells$83,000
U01 · FY2017 · DK · contact PI
Developing 3D Craniofacial Morphometry Data and Tools to Transform Dysmorphology$653,410
U01 · FY2016 · DE
Harnessing natural stem cell-based strategies for mammalian dental renewal$634,000
R35 · FY2016 · DE · contact PI
The role of Hippo and YAP/TAZ in dental renewal$396,250
R01 · FY2016 · DE · contact PI
Regulation of distinct pools of intestinal stem cells$356,625
U01 · FY2016 · DK · contact PI
Regulation of distinct pools of intestinal stem cells$50,000
U01 · FY2016 · DK · contact PI
2016 Craniofacial Morphogenesis and Tissue Regeneration Gordon Research Conference and Gordon Research Seminar$16,000
R13 · FY2016 · DE · contact PI
Developing 3D Craniofacial Morphometry Data and Tools to Transform Dysmorphology$651,972
U01 · FY2015 · DE
The role of Bmi1 in regulation of dental stem cells$401,821
R01 · FY2015 · DE · contact PI
The role of Hippo and YAP/TAZ in dental renewal$396,250
R01 · FY2015 · DE · contact PI
Regulation of distinct pools of intestinal stem cells$356,625
U01 · FY2015 · DK · contact PI
University of California Tissue Regeneration Resource Center (UCTRRC)$197,346
R34 · FY2015 · DE
Regulation of distinct pools of intestinal stem cells$50,000
U01 · FY2015 · DK · contact PI
Developing 3D Craniofacial Morphometry Data and Tools to Transform Dysmorphology$709,333
U01 · FY2014 · DE
The role of Bmi1 in regulation of dental stem cells$471,424
R01 · FY2014 · DE · contact PI
Regulation of distinct pools of intestinal stem cells$355,688
U01 · FY2014 · DK · contact PI
The role of Bmi1 in regulation of dental stem cells$352,260
R01 · FY2013 · DE · contact PI
The role of Bmi1 in regulation of dental stem cells$69,326
R01 · FY2013 · DE · contact PI
The role of Bmi1 in regulation of dental stem cells$366,938
R01 · FY2012 · DE · contact PI
The role of Sprouty genes in development of mammalian external genitalia$150,000
R01 · FY2012 · DK · contact PI
The role of Spry2 in regulation of bone formation$74,160
R03 · FY2012 · AR · contact PI
The role of Bmi1 in regulation of dental stem cells$366,938
R01 · FY2011 · DE · contact PI
The role of Sprouty genes in development of the circumvallate papilla$228,981
R21 · FY2011 · DC · contact PI
The role of Spry2 in regulation of bone formation$74,160
R03 · FY2011 · AR · contact PI
An evolutionary-developmental approach to stem cells using teeth as a model$2,317,500
DP2 · FY2010 · OD · contact PI
The Role of microRNAs in Tooth Regeneration using the Mouse Incisor Model$229,433
R21 · FY2010 · DE · contact PI
The role of Sprouty genes in development of the circumvallate papilla$197,797
R21 · FY2010 · DC · contact PI
The role of Spry2 in regulation of bone formation$77,250
R03 · FY2010 · AR · contact PI
The Role of microRNAs in Tooth Regeneration using the Mouse Incisor Model$193,125
R21 · FY2009 · DE · contact PI
Analysis of the Role of Sprouty Genes in Tooth Development$127,464
K08 · FY2009 · DE · contact PI
Analysis of the Role of Sprouty Genes in Tooth Development$25,259
K08 · FY2009 · DE · contact PI
Analysis of the Role of Sprouty Genes in Tooth Development$125,010
K08 · FY2008 · DE · contact PI
Analysis of the Role of Sprouty Genes in Tooth Development$124,200
K08 · FY2007 · DE · contact PI