Tumor pyruvate kinase as key regulator of cancer metabolism
$88,646K99FY2011CANIH
Sanford Burnham Prebys Medical Discovery Institute, La Jolla CA
Investigators
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Abstract
DESCRIPTION (provided by applicant): None provided. PUBLIC HEALTH RELEVANCE:: My project seeks to understand the role of pyruvate kinase as regulator of cancer metabolism. Insights into glutamine influx of proliferating cells will reveal new drug targets and generate new regimes for diagnosis and treatment of cancer patients.
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