PROTEIN TRAFFICKING IN NEUROENDOCRINE CELLS

University Of North Carolina Chapel Hill, Chapel Hill NC

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Linked publications & trials

Abstract

DESCRIPTION: Dr. Milgram proposes experiments aimed at increasing understanding of mechanisms of protein sorting in neuroendocrine cells. The following two questions will be addressed: (1) What are the proteins that interact with routing determinants in the peptidylglycine alpha-amidating monooxygenase (PAM) cytosolic domain? (2) What is the role of the novel PAM cytosolic domain binding protein, BP1?