MYOSIN-X A NOVEL MYOSIN WITH PH DOMAINS
$101,150R29FY2000DCNIH
University Of North Carolina Chapel Hill, Chapel Hill NC
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Abstract
DESCRIPTION: This application outlines a series of experiments The applicant intends to outline hypotheses for the cell biological functions of myosin-X by determining its localization in tissues and cells. He will then define the basic structural and biochemical properties of this class of myosin and its tail domain and test whether purified myosin-X actually functions as a molecular motor in in vitro motility assays.
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