Potential Biomarkers for Filovirus Vaccine Efficacy

National Institute Of Allergy And Infectious Diseases

Investigators

Abstract

This IAA supports the studies to assess the expression and biological activity among the twelve subtypes of IFN-alpha and three subtypes of IFN-Iambda with the goal of showing that expression patterns of IFNalpha and IFN-Iambda will serve as a rapid marker for protective vaccination against Ebola and other filovirus infections.