ENERGY METABOLISM OF PANCREATIC ISLETS:OXYGENATIONANTIOXIDANTS

$12,835P41FY2009RRNIH

University Of Minnesota, Minneapolis MN

Investigators

Linked publications & trials

Paper 38212349 Paper 37266390 Paper 35012890 Paper 34484102 Paper 33517108 Paper 32951240 Paper 32840468 Paper 32581994 Paper 32472038 Paper 32467648 Paper 32424236 Paper 32187742 Paper 31796137 Paper 31751499 Paper 31471575 Paper 31352813 Paper 31156078 Paper 30394325 Paper 30242896 Paper 30170080 Paper 29152411 Paper 29108528 Paper 29073724 Paper 28698108 Paper 28616384 Paper 27996049 Paper 27981651 Paper 27660604 Paper 27574313 Paper 27498919 Paper 27266965 Paper 27232951 Paper 27114896 Paper 26712657 Paper 26667600 Paper 26656578 Paper 26592718 Paper 26553916 Paper 26534967 Paper 26485382 Paper 26414616 Paper 26373461 Paper 26364023 Paper 26348971 Paper 26287448 Paper 26163815 Paper 26113614 Paper 26098931 Paper 26095521 Paper 26050933 Paper 26001258 Paper 25905715 Paper 25904240 Paper 25892746 Paper 25837601 Paper 25789084 Paper 25581510 Paper 25571378 Paper 25564236 Paper 25541100 Paper 25501983 Paper 25490453 Paper 25479750 Paper 25462690 Paper 25451478 Paper 25446943 Paper 25404992 Paper 25346367 Paper 25255945 Paper 25247405 Paper 25205331 Paper 25192576 Paper 25133665 Paper 25111731 Paper 25105832 Paper 25070004 Paper 25057192 Paper 25036008 Paper 24961416 Paper 24948590 Paper 24919566 Paper 24919180 Paper 24911888 Paper 24803104 Paper 24768314 Paper 24745476 Paper 24676563 Paper 24664527 Paper 24657355 Paper 24649429 Paper 24604286 Paper 24598439 Paper 24568703 Paper 24549182 Paper 24529364 Paper 24526186 Paper 24523028 Paper 24512818 Paper 24478130 Paper 24462505

Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Energy Metabolism of Pancreatic Islets: Effects of Oxygenation Status and Antioxidants (in collaboration with Dr. Klearchos Papas, Surgery): Islet transplantation is a highly promising treatment method for restoring normoglycemia in a subpopulation of patients with Type 1 diabetes. In this collaboration with the Diabetes Institute for Immunology and Transplantation our goal is to assess the pre- and post-transplant viability of pancreatic islets using MRS. We started the project by comparing anaerobic and oxidative carbohydrate metabolism (as measured by 13C NMR) and energy status (as measured by 31P NMR) of porcine islet cultures and islet models under normoxia versus hypoxia/anoxia in the presence and absence of antioxidants.

View original record on NIH RePORTER →