Mechanisms of Action

$341,282P50FY2009GMNIH

University Of Pittsburgh At Pittsburgh, Pittsburgh PA

Investigators

Linked publications & trials

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Abstract

The primary objectives of this subproject are to test the hypotheses: 1): Protocolized resuscitation reduces expression of circulating markers of: i.) inflammation, ii.) cellular hypoxia, iii.) oxidative stress, and iv.) coagulation/thrombosis. 2): The clinical efficacy of protocolized resuscitation is associated with reduced expression of circulating markers of: i.) inflammation, ii.) cellular hypoxia, iii.) oxidative stress, and iv.) coagulation/thrombosis.

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