Remodeling Histology

$51,029U19FY2009AINIH

University Of California, San Diego, La Jolla CA

Investigators

Linked publications & trials

Paper 39006429 Paper 38702102 Paper 38335270 Paper 37928558 Paper 37865091 Paper 37413923 Paper 36473503 Paper 35835621 Paper 35662655 Paper 35406705 Paper 34721399 Paper 34525218 Paper 34364539 Paper 33679760 Paper 33661765 Paper 33637594 Paper 33374255 Paper 33358894 Paper 33306487 Paper 33160971 Paper 32958689 Paper 32950684 Paper 32946563 Paper 32672387 Paper 32372469 Paper 32249942 Paper 32176320 Paper 32134149 Paper 32086831 Paper 32014112 Paper 31965606 Paper 31369800 Paper 31201889 Paper 30932909 Paper 30877073 Paper 30365391 Paper 30135581 Paper 29709669 Paper 29616048 Paper 29522852 Paper 29339444 Paper 29336282 Paper 29315623 Paper 28959799 Paper 28958904 Paper 28889952 Paper 28827284 Paper 28667163 Paper 28366795 Paper 28279492 Paper 28275260 Paper 28275141 Paper 28087226 Paper 27826095 Paper 27799535 Paper 27531077 Paper 27212082 Paper 27142393 Paper 27001159 Paper 26748035 Paper 26746844 Paper 26656423 Paper 26378386 Paper 26355153 Paper 26233928 Paper 26233926 Paper 26209626 Paper 26100084 Paper 25898689 Paper 25789702 Paper 25680454 Paper 25605931 Paper 25550230 Paper 25539192 Paper 25525738 Paper 25236785 Paper 24973820 Paper 24835503 Paper 24835176 Paper 24794009 Paper 24623133 Paper 24613728 Paper 24590208 Paper 24239745 Paper 24210841 Paper 23967196 Paper 23688412 Paper 23677475 Paper 23667652 Paper 23623266 Paper 23616302 Paper 23547101 Paper 23499929 Paper 23334208 Paper 23011799 Paper 22942422 Paper 22865552 Paper 22791291 Paper 22327070 Paper 22169337

Abstract

Core B "remodeling histology" will support all four individual projects by providing quantitative analysis of airway remodeling end-points in mice subjected to repetitive allergen challenge. The core will quantitate structural remodeling changes in the airway focusing particular on peribronchial fibrosis and smooth muscle changes. The core will perform staining (trichrome), and immunostaining (a-smooth muscle actin, collagen III and V) of coded lung sections and utilize image analysis to quantify results. Additional assays available in the core include total lung collagen measurements, and assessment of epithelial mucus expression.

View original record on NIH RePORTER →