MECHANISMS OF HEMATOPOIESIS IN AIDS

$412,705R01FY2000HLNIH

Massachusetts General Hospital, Boston MA

Investigators

Linked publications & trials

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Abstract

DESCRIPTION: This grant application is aimed at improving the understanding of the contribution of impaired T cell production to the effects of HIV. First, the investigator will examineif there is impairment in lymphopoietic capacity of HIV+ bone marrows. Second, the investigator will examine the expression of gene products that regulate hematopoiesis. Third, the investigator will examine the effects of AIDS medications on T cell production.

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