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IMMUNOHISTOCHEMICAL LOCALIZATION OF LEUKOCYTE &INTERMEDIATE FILAMENT ANTIBODIES

$50,440P51FY2000RRNIH

Harvard University (Medical School), Boston MA

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Abstract

In order to improve our diagnostic pathology capabilities, we are systematically evaluating commerciallyvailableantibodies directed against human cells/tissues for application in the nonhuman primate species housed at the NERPRC Antibodies are selected for potential usefulness in diagnostic and/or experimental pathology, and for effectiveness in formalin-fixed, paraffin-embedded tissues In one study we were able to identify 21 of 21 antigens in 4 macaque species and 17 of 21 for New World

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