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Core--Biological assessment laboratory

$295,888P50FY2000CANIH

University Of Miami Coral Gables, Coral Gables FL

Investigators

Mary A Fletcher

Linked publications & trials

Paper 36375341Paper 23526866Paper 23107843Paper 22571442Paper 22545977Paper 21932396Paper 21109047Paper 21086876Paper 19837201Paper 19568967Paper 19424809Paper 18805249Paper 18677078Paper 18500579Paper 18440406Paper 18062059Paper 18001230Paper 17152452Paper 17083664Paper 16700640Paper 16698362Paper 16523528Paper 16304622Paper 16247785Paper 16162045Paper 15882730Paper 15796638Paper 15576258Paper 15546227Paper 15069763Paper 15053723Paper 15018681Paper 14972470Paper 14692040Paper 12764216Paper 12703650Paper 12683742Paper 12614833Paper 12414757Paper 12140342Paper 12115380Paper 11811628Paper 11165941Paper 11000519Paper 10875259

Abstract

The Laboratory Core will provide the assessments of soluble mediators, lymphocyte surface markers, hematological parameters and lymphocyte function in support of the scientific agenda of this Center. The following assays will be done by the Laboratory Core: Cortisol and catecholamines, norepinephrine (NE) and epinephrine (E) in urine. Testosterone, estradiol,. Estrone, sex hormone binding globulin (SHBG) and dehydroepiandrosterone-sulfate (DHEA-S) and NPY in plasma. Natural killer cell cytotoxicity (NKCC) against the tumor cell target, K562. NKCC against the tumor cell target, K562, after ex vivo exposure to interferon-gamma (IFN-gamma). Number and percent of NK (C56+CD3-), CD3+CD4+ and CD3+CD8+ lymphocytes using 4 color flow cytometry.

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