MR MICROSCOPY OF DISTAL AIRWAYS: STATIC IMAGING

$30,045P41FY2000RRNIH

Duke University, Durham NC

Investigators

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Abstract

Spectroscopy of guinea pig lungs will be studied with the use of hyper-polarized 3He. The goal is to measure the fundamental parameters, T1, T2, T2*, and perhaps D as a function of inflation. Our hypothesis is that one of these parameters will be particularly sensitive to changes in the microstructure of the alveoli.

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