DETECT AMYLOID PROTEIN IN BRAIN

$3,854P41FY2000RRNIH

University Of Illinois Urbana-Champaign, Champaign IL

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Abstract

We are investigafing the soluton dynamics of spectrin. A cysteine residue has been added th the sequence at various points near a purported fleAbel hinge region. Labeling the cysteine with fluorescence probes and applying time-resolved anisotropy we are evaluating the local and segmental motion of the spectrum molecule.

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