ULTRASENSITIVE DETECTION OF OF PROTEIN &DNA ADDUCTS BY FLUORESCENCE &HPLC

$13,842P41FY2000RRNIH

Massachusetts Institute Of Technology, Cambridge MA

Investigators

Linked publications & trials

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Abstract

HPLC separation system has been combined with an ultrasensitive detection technology to detect and identify BPT and BPT adducts of proteins at about 10 attomole level. The experiments focus on quantification of BPDE adducts on human lung histones and human serum albumin.

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