REFLECTED LIGHT FOR DETECTING DYSPLASIA IN URINARY BLADDER

$13,842P41FY2000RRNIH

Massachusetts Institute Of Technology, Cambridge MA

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Abstract

We studied reflectance spectra collected in vitro and in vivo from different sites in urinary bladder by means of a model, similar to one used in colonic studies. The model takes into account propagation of light in presence of oxy- and de-oxy- hemoglobin and scattering on collagen fibers and provides parameters that characterize hemoglobin concentration and average scatterer size for dysplastic and non-dysplastic tissues.

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