FLUORESCENCE PRINCIPAL COMPONENT ANALYSIS OF ALZHEIMERS DISEASE

$13,842P41FY2000RRNIH

Massachusetts Institute Of Technology, Cambridge MA

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Abstract

Fluorescence spectra collected from control and Alzheimer's diseased brain tissue specimens of temporal cortex were analyzed by principal component analysis. Although the spectra show only subtle differences, which are largely masked by sample-to-sample variation, principal component analysis differentiates Alzheimer's diseased from control brain tissue.

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