BACTERIAL GENOME RESTRICTION DIGESTS BY FLOW CYTOMETRIC DNA FRAGMENT SIZING

$15,323P41FY2000RRNIH

University Of Calif-Los Alamos Nat Lab, Los Alamos NM

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Abstract

DNA fragment size analysis by flow cytometry has been applied to the analysis of restriction enzyme digest of 3 bacterial gnomes E. coli, E. herbicola, and E. erwinia. Distinct restriction fragment fingerprints were observed and served as the basis for discriminating among the three species. Details are contained in a Research Highlight and a publication that is in press in Cytometry.

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