CLINICAL PHARMACOLOGY AND ANALYTICAL CHEMISTRY CORE

$253,048P30FY2006AINIH

Univ Of North Carolina Chapel Hill, Chapel Hill NC

Investigators

Linked publications & trials

Paper 39720558 Paper 39678390 Paper 39666731 Paper 39636896 Paper 39493307 Paper 39465466 Paper 39431507 Paper 39431505 Paper 39399681 Paper 39352388 Paper 39348391 Paper 39327860 Paper 39315264 Paper 39288937 Paper 39266889 Paper 39249627 Paper 39218437 Paper 39110550 Paper 39095615 Paper 39052733 Paper 39019846 Paper 38987993 Paper 38973065 Paper 38947061 Paper 38913710 Paper 38905486 Paper 38905479 Paper 38905473 Paper 38867283 Paper 38848441 Paper 38838873 Paper 38829049 Paper 38756763 Paper 38720636 Paper 38703339 Paper 38699336 Paper 38670612 Paper 38643166 Paper 38632603 Paper 38612641 Paper 38600088 Paper 38517670 Paper 38507583 Paper 38498872 Paper 38489140 Paper 38466776 Paper 38462671 Paper 38449916 Paper 38426750 Paper 38423105 Paper 38422171 Paper 38421512 Paper 38408732 Paper 38380946 Paper 38364812 Paper 38349228 Paper 38333992 Paper 38327572 Paper 38294704 Paper 38293246 Paper 38253452 Paper 38239974 Paper 38236978 Paper 38224361 Paper 38215160 Paper 38214547 Paper 38195955 Paper 38180885 Paper 38160309 Paper 38159909 Paper 38150573 Paper 38150572 Paper 38145241 Paper 38133580 Paper 38131623 Paper 38126350 Paper 38110289 Paper 38086007 Paper 38085428 Paper 38061223 Paper 38055722 Paper 38023712 Paper 38011589 Paper 37995110 Paper 37994517 Paper 37986885 Paper 37977197 Paper 37976419 Paper 37969014 Paper 37963086 Paper 37956200 Paper 37950348 Paper 37949070 Paper 37910437 Paper 37861689 Paper 37843370 Paper 37824787 Paper 37814498 Paper 37797892 Paper 37773048

Abstract

The purpose of the Clinical Pharmacology and Analytical Chemistry Core (Core E) is to provide a[unreadable] centralized unit to facilitate the pharmacological and analytical studies of HIV/AIDS related clinical,[unreadable] translational, and basic science research at UNC-CH and at our collaborating institutions, and to establish[unreadable] collaboration with AIDS investigators at other national and international institutions. We bring together a[unreadable] group of established investigators, collaborators, and advisors in analytical chemistry, pharmacology, and[unreadable] related fields. These investigators oversee a modern and well-equipped, composite analytical laboratory.[unreadable] The services provided to the HIV/AIDS investigators by Core E include specimen procurement and handling[unreadable] of HIV infected and noninfected material; pharmacologic consultation and support for pharmacokinetic and[unreadable] pharmacodynamic investigations; analysis of samples; and interpretation of pharmacologic results. All[unreadable] analyses are conducted in a CLIA-certified, state of the art analytical laboratory that includes high[unreadable] performance liquid chromatography, gas chromatography, capillary electrophoresis, nuclear magnetic[unreadable] resonance spectroscopy, and mass spectrometry. The laboratory is centrally located and has convenient[unreadable] access for the HIV/AIDS investigators at UNC-CH.[unreadable] Prior to the establishment of Core E, HIV/AIDS investigators struggled through their analytical and[unreadable] pharmacologic needs by relying on the undependable timetables of unfunded colleagues or by contracting[unreadable] out the studies to costly private facilities. In most cases important pharmacological studies were bypassed[unreadable] for a lack of funding or reliable expertise. Core E now fills the analytical and pharmacological needs of[unreadable] HIV/AIDS researchers without undue financial burden on their primary grants. In addition, the availability of[unreadable] this facility has stimulated new and important HIV/AIDS related drug research, funding, and interdisciplinary[unreadable] collaborations.

View original record on NIH RePORTER →