Efficacy of Voice Treatment for Parkinson's Disease

University Of Colorado, Boulder CO

Investigators

Linked publications & trials

Abstract

Oral communication is a vital element in education, employment, social functioning and self-expression. At least 89% of the one and one half million individuals diagnosed with idiopathic Parkinson' disease (IPD) have a speech or voice disorder, yet only 3-4% receive speech treatment. Generation of the first voice treatment efficacy data has provided important information about mechanisms underlying the voice disorder in IPD and has identified fundamental elements of treatment-related change. The work proposed here builds upon this well-established foundation of data to accomplish the following aims: (1) evaluate the system-wide generalized impact of voice and articulation treatments of speech articulation, facial expression swallowing; (2) evaluate the system-wide generalized impact of voice and articulation on treatments on limb gesture and limb motor functioning; (3) investigate laryngeal sensorimoter gating and internal cueing in IPD and the impact on voice and articulation treatments on such deficits; (4) investigate the effects of voice treatment on brain function activity using Positron Emission Tomography (PET). These studies will simultaneously advance knowledge of basic mechanisms underlying disordered voice and effective treatment, while directly contributing to improved communication and quality of life in individuals with neurological disorders.