Structural Studies of AIDS Proteins by NMR
$0Z01FY2005DKNIH
Diabetes, Digestive, Kidney Diseases
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Abstract
Work has been carried out on a number of structural problems related to proteins derived from retroviruses and of relevance to the pathogenesis and clinical manifestation of AIDS. These include the potent anti HIV protein cyanovirin-N, variants thereof and HIV-1 protease. In particular the foldind and interaction of CV-N with carbohydrates has been investigated.
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